2014
Sleep in Patients with Restrictive Lung Disease
Won CH, Kryger M. Sleep in Patients with Restrictive Lung Disease. Clinics In Chest Medicine 2014, 35: 505-512. PMID: 25156766, DOI: 10.1016/j.ccm.2014.06.006.ChaptersConceptsRestrictive lung diseaseLung diseaseObesity hypoventilation syndromeInterstitial lung diseasePathophysiology of sleepImpact of treatmentOverall prognosisVentilatory defectHypoventilation syndromeImpaired ventilationDaytime fatigueSleep disruptionRelated symptomsSleep disordersSleep qualityDiffusion impairmentNeuromuscular diseaseDiseasePatientsPathophysiologySleepHypoxemiaHypercarbiaPrognosisDysfunction
1993
Effects of Zolpidem and Triazolam on Sleep and Respiration in Mild to Moderate Chronic Obstructive Pulmonary Disease
Steens R, Pouliot Z, Millar T, Kryger M, George C. Effects of Zolpidem and Triazolam on Sleep and Respiration in Mild to Moderate Chronic Obstructive Pulmonary Disease. Sleep 1993, 16: 318-326. PMID: 8341892, DOI: 10.1093/sleep/16.4.318.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseModerate chronic obstructive pulmonary diseaseObstructive pulmonary diseaseEffects of zolpidemPulmonary diseaseDrug conditionsNocturnal arterial oxygen desaturationArterial oxygen desaturationApnea-hypopnea indexGroup of patientsArterial oxygen saturationNumber of awakeningsTotal sleep timeHours of sleepSignificant differencesSubjective sleep variablesNew hypnotic agentOxygen desaturationCrossover studyHypnotic agentsSleep problemsSleep qualityOxygen saturationSleep efficiencyActive drug
1987
The Effect of Excessive Ethanol Ingestion on Sleep in Severe Chronic Obstructive Pulmonary Disease
Easton P, West P, Meatherall R, Brewster J, Lertzman M, Kryger M. The Effect of Excessive Ethanol Ingestion on Sleep in Severe Chronic Obstructive Pulmonary Disease. Sleep 1987, 10: 224-233. PMID: 3629084, DOI: 10.1093/sleep/10.3.224.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlcoholic IntoxicationFemaleHeart RateHumansLung Diseases, ObstructiveMaleMiddle AgedOxygenRespirationSleepSleep StagesConceptsChronic obstructive pulmonary diseaseSevere chronic obstructive pulmonary diseaseObstructive pulmonary diseaseSleep timePulmonary diseaseHeart rateEmphysematous chronic obstructive pulmonary diseaseExcessive ethanol ingestionSignificant O2 desaturationArterial oxygen saturationIngestion of alcoholDose of ethanolSleep stagesExcessive alcohol ingestionTotal sleep timeMean heart ratePremature ventricular contractionsCOPD altersAlcohol ingestionO2 desaturationEthanol ingestionOxygen saturationVentricular contractionsREM timeSerum ethanolOxygenation and Breathing Pattern During Phasic and Tonic REM in Patients with Chronic Obstructive Pulmonary Disease
George C, West P, Kryger M. Oxygenation and Breathing Pattern During Phasic and Tonic REM in Patients with Chronic Obstructive Pulmonary Disease. Sleep 1987, 10: 234-243. PMID: 3629085, DOI: 10.1093/sleep/10.3.234.Peer-Reviewed Original ResearchMeSH KeywordsAgedElectroencephalographyFemaleHumansLung Diseases, ObstructiveMaleOxygenRespirationSleep StagesSleep, REMConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseTonic REMPhasic REMBreathing patternOxygen desaturationPulmonary diseaseSevere chronic obstructive pulmonary diseaseBreathing pattern changesAwake SaO2Nadir SaO2Total REMRespiratory neuronsMore desaturationMotor neuronsOxygen saturationREM sleepSaO2SaO2 differenceTransient decreaseRespiratory amplitudeNight studiesSleepDesaturationPatientsHypercapnia and Sleep O2 Desaturation in Chronic Obstructive Pulmonary Disease
Kryger M, Rogelio P, Conway W, Roth T, Anthonisen N, George C. Hypercapnia and Sleep O2 Desaturation in Chronic Obstructive Pulmonary Disease. Sleep 1987, 10: 216-223. PMID: 3629083, DOI: 10.1093/sleep/10.3.216.Peer-Reviewed Original ResearchMeSH KeywordsAgedBody WeightFemaleHumansHypercapniaLung Diseases, ObstructiveMaleMiddle AgedOxygenSleepConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseBlue bloatersPink puffersSleep hypoxemiaPulmonary diseaseO2 desaturationHypoxemic chronic obstructive pulmonary diseaseNocturnal Oxygen Therapy TrialBetter lung functionArterial blood gasesWide clinical spectrumHypercapnic patientsSame PaO2Sleep oxygenationSleep SaO2Airflow obstructionHypoxemic patientsPulmonary hypertensionCOPD populationHypercapnic groupMost patientsNormocapnic patientsLung functionBlood gases
1986
Alteration in Breathing Pattern with Progression of Chronic Obstructive Pulmonary Disease1,2
Loveridge B, West P, Kryger M, Anthonisen N. Alteration in Breathing Pattern with Progression of Chronic Obstructive Pulmonary Disease1,2. American Journal Of Respiratory And Critical Care Medicine 1986, 134: 930-934. PMID: 3777689, DOI: 10.1164/arrd.1986.134.5.930.Peer-Reviewed Original ResearchMeSH KeywordsForced Expiratory VolumeHumansLung Diseases, ObstructiveRespirationSpirometryTidal VolumeTime FactorsConceptsChronic obstructive pulmonary diseaseRespiratory failureSevere groupBreathing patternRespiratory inductance plethysmographStable chronic obstructive pulmonary diseaseRespiratory failure groupChronic obstructive pulmonaryObstructive pulmonary diseaseSignificant decreaseVT/TISeverity of diseasePulmonary diseaseAcute reliefFailure groupSupplemental O2Minute ventilationVentilatory controlTidal volumeModerate groupMechanical abnormalitiesInductance plethysmographBreathing frequencySeated positionFEV1
1985
Sleep in Restrictive Lung Disorders
Kryger M. Sleep in Restrictive Lung Disorders. Clinics In Chest Medicine 1985, 6: 675-677. PMID: 3853479, DOI: 10.1016/s0272-5231(21)00404-4.Peer-Reviewed Original ResearchMeSH KeywordsArousalHumansKyphosisLungLung Diseases, ObstructiveOxygenPulmonary FibrosisScoliosisSleep Stages
1984
Breathing Patterns in Patients with Chronic Obstructive Pulmonary Disease1,2
Loveridge B, West P, Anthonisen N, Kryger M. Breathing Patterns in Patients with Chronic Obstructive Pulmonary Disease1,2. American Journal Of Respiratory And Critical Care Medicine 1984, 130: 730-3. PMID: 6497155, DOI: 10.1164/arrd.1984.130.5.730.Peer-Reviewed Original ResearchMeSH KeywordsFemaleForced Expiratory VolumeHumansLung Diseases, ObstructiveMalePlethysmographyPulmonary Gas ExchangeRespirationTidal VolumeTime FactorsConceptsChronic obstructive pulmonary diseaseCOPD groupRespiratory inductance plethysmographRib cageStable chronic obstructive pulmonary diseaseSex-matched control subjectsChronic obstructive pulmonaryObstructive pulmonary diseaseTi/TtotCOPD patientsMean PaO2Pulmonary diseaseControl subjectsMinute ventilationExpiratory timeInspiratory flowSitting positionTidal volumeNormal subjectsBreathing patternInductance plethysmographPatientsRespiratory cycleMean numberNeural control
1982
Sleep, Arousals, and Oxygen Desaturation in Chronic Obstructive Pulmonary Disease
Fleetham J, West P, Mezon B, Conway W, Roth T, Kryger M. Sleep, Arousals, and Oxygen Desaturation in Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 1982, 126: 429-33. PMID: 7125332, DOI: 10.1164/arrd.1982.126.3.429.Peer-Reviewed Original ResearchMeSH KeywordsAgedArousalFemaleHumansHypercapniaHypoxiaLung Diseases, ObstructiveMaleMiddle AgedOxygenOxygen Inhalation TherapySleep Apnea SyndromesConceptsOxygen desaturationArousal frequencySleep qualityChronic obstructive pulmonary diseaseAge-matched normal subjectsLower mean SaO2Role of hypoxemiaArterial oxygen desaturationObstructive pulmonary diseaseRoom air breathingArterial O2 saturationPoor sleep qualityReduced sleep timeSleep stage changesApneic episodesPulmonary functionOxygen therapyPulmonary diseaseSupplemental oxygenMean SaO2Sleep disruptionREM sleepNormal subjectsO2 saturationPatients
1980
The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3
Fleetham J, Bradley C, Kryger M, Anthonisen N. The Effect of Low Flow Oxygen Therapy on the Chemical Control of Ventilation in Patients with Hypoxemic COPD1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 833-40. PMID: 6779682, DOI: 10.1164/arrd.1980.122.6.833.Peer-Reviewed Original ResearchMeSH KeywordsCarbon DioxideHumansHypoxiaLung Diseases, ObstructiveOxygen Inhalation TherapyRespirationTime FactorsConceptsChronic obstructive pulmonary diseaseHypoxemic chronic obstructive pulmonary diseaseOxygen therapyHypoxic responseLow-flow oxygen therapyCentral ventilatory driveFlow oxygen therapyNocturnal oxygen therapyObstructive pulmonary diseaseArterial O2 saturationNocturnal oxygenPulmonary diseaseSuch patientsVentilatory driveMinute ventilationInspiratory flowO2 saturationPatientsTherapyContinuous oxygenMonthsHypoxiaInitial responseHypoxemiaVentilationChemical Control of Ventilation and Sleep Arterial Oxygen Desaturation in Patients with COPD1–3
Fleetham J, Mezon B, West P, Bradley C, Anthonisen N, Kryger M. Chemical Control of Ventilation and Sleep Arterial Oxygen Desaturation in Patients with COPD1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 583-9. PMID: 7436124, DOI: 10.1164/arrd.1980.122.4.583.Peer-Reviewed Original ResearchConceptsO2 saturationSleep desaturationVentilatory sensitivityRapid eye movement (REM) sleepNocturnal changesArterial oxygen desaturationLowest O2 saturationHypoxic ventilatory responseArterial O2 saturationEye movement sleepHypoxemic COPDNocturnal desaturationOxygen desaturationLung functionBlood gasesVentilatory responseMovement sleepVentilatory controlPatientsMaximal desaturationSleepDesaturationSleep stagesHypercapniaWakefulness