1998
Susceptibility of LDL to Oxidative Stress in Obstructive Sleep Apnea
Wali S, Bahammam A, Massaeli H, Pierce G, Iliskovic N, Singal P, Kryger M. Susceptibility of LDL to Oxidative Stress in Obstructive Sleep Apnea. Sleep 1998, 21: 290-296. PMID: 9595608, DOI: 10.1093/sleep/21.3.290.Peer-Reviewed Original ResearchConceptsLow-density lipoproteinObstructive sleep apneaOSA patientsNormal controlsOxidative stressSleep apneaPatient groupSevere hypoxiaSusceptibility of LDLFree radical challengeSame age groupCPAP therapySevere hypoxemiaRed blood cellsCardiovascular diseaseAntioxidant reserveGeneral populationPatientsIndividual low-density lipoproteinHours of exposureControl groupAge groupsGlutathione peroxidaseBlood cellsConjugated dienes
1989
Respiration and Abnormal Sleep in Patients with Congestive Heart Failure
Hanly B, Millar T, Steljes D, Boert R, Frais M, Kryger M. Respiration and Abnormal Sleep in Patients with Congestive Heart Failure. CHEST Journal 1989, 96: 480-488. PMID: 2766808, DOI: 10.1378/chest.96.3.480.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureStage 2 NREM sleepSlow-wave sleepSleep stage changesNREM sleepHyperpneic phaseHeart failureREM sleepAwake arterial oxygen saturationStable congestive heart failureSevere congestive heart failureStage 1Mean minimum SaO2Outcomes of patientsNumber of arousalsArterial oxygen saturationStage 1 sleepMinimum SaO2Severe hypoxemiaArterial oxygenationSignificant hypoxemiaClinical statusMean durationAbnormal sleep
1982
Diagnosis of sleep breathing disorders in a general hospital. Experience and recommendations.
Kryger M, Mezon B, Acres J, West P, Brownell L. Diagnosis of sleep breathing disorders in a general hospital. Experience and recommendations. JAMA Internal Medicine 1982, 142: 956-9. PMID: 7082118, DOI: 10.1001/archinte.142.5.956.Peer-Reviewed Original ResearchDiagnosis of Sleep Breathing Disorders in a General Hospital: Experience and Recommendations
Kryger M, Mezon B, Acres J, West P, Brownell L. Diagnosis of Sleep Breathing Disorders in a General Hospital: Experience and Recommendations. JAMA Internal Medicine 1982, 142: 956-958. DOI: 10.1001/archinte.1982.00340180114021.Peer-Reviewed Original Research
1980
Sleep apnea in acromegaly
Mezon B, West P, Maclean J, Kryger M. Sleep apnea in acromegaly. The American Journal Of Medicine 1980, 69: 615-623. PMID: 7424949, DOI: 10.1016/0002-9343(80)90477-5.Peer-Reviewed Original ResearchConceptsUpper airway obstructionSleep apnea syndromeAirway obstructionApnea syndromeSomnolent patientsSevere hypoxemiaPharyngeal airwayUpper airwayNormal sleepLarge tonguePatientsAcromegalyObstructionAirwaySyndromeSleepPeriodic obstructionTongueHypoxemiaSomnolenceTracheostomyApneaEndoscopyLarynxPharynx
1978
Impaired Oxygenation During Sleep in Excessive Polycythemia of High Altitude: Improvement with Respiratory Stimulation
Kryger M, Glas R, Jackson D, McCullough R, Scoggin C, Grover R, Weil J. Impaired Oxygenation During Sleep in Excessive Polycythemia of High Altitude: Improvement with Respiratory Stimulation. Sleep 1978, 1: 3-17. PMID: 756057, DOI: 10.1093/sleep/1.1.3.Peer-Reviewed Original ResearchConceptsMedroxyprogesterone acetatePolycythemic patientsSevere hypoxemiaExcessive polycythemiaDouble-blind crossover trialMean lowest SaO2REM stage sleepDegree of hypoxemiaHigh-altitude residentsAwake SaO2Nocturnal SaO2Sleep hypoxemiaStage sleepImpaired oxygenationCrossover trialMean SaO2Lowest SaO2Control subjectsHypoxemiaTherapeutic effectOxygen saturationExcessive hypoxemiaSaO2Breathing patternPatients