2022
Comparison of Ring Pulse Oximetry Using Reflective Photoplethysmography and PSG in the Detection of OSA in Chinese Adults: A Pilot Study
Zhao R, Xue J, Zhang X, Peng M, Li J, Zhou B, Zhao L, Penzel T, Kryger M, Dong XS, Gao Z, Han F. Comparison of Ring Pulse Oximetry Using Reflective Photoplethysmography and PSG in the Detection of OSA in Chinese Adults: A Pilot Study. Nature And Science Of Sleep 2022, 14: 1427-1436. PMID: 36003191, PMCID: PMC9394522, DOI: 10.2147/nss.s367400.Peer-Reviewed Original ResearchEvents/hOxygen desaturation indexIntraclass correlation coefficientPulse oximetryChinese adultsThreshold of AHIObstructive sleep apneaDetection of OSAPositive likelihood ratioChinese Han subjectsOxygen desaturationDesaturation indexSleep apneaMean ageSimultaneous polysomnographyOxygen saturationPSG-AHIPolysomnographySleep laboratorySleep timePilot studyHan subjectsAHIOximetryCumulative percentage
2012
Respiratory Event Detection by a Positive Airway Pressure Device
Berry RB, Kushida CA, Kryger MH, Soto-Calderon H, Staley B, Kuna ST. Respiratory Event Detection by a Positive Airway Pressure Device. Sleep 2012, 35: 361-367. PMID: 22379242, PMCID: PMC3274337, DOI: 10.5665/sleep.1696.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaEvents/hrPositive airway pressure devicesApnea indexHypopnea indexPAP devicesRespiratory eventsSleep disorders centerPressure deviceBetter treatment efficacyRespiratory event detectionOxygen desaturationSleep apneaPAP treatmentBland-Altman analysisDisorders CenterPolysomnographyTreatment efficacyAHIInadequate treatmentManual scoringHypopnea detectionTrue negative eventsHrTreatment
2003
Morbidity and mortality in obstructive sleep apnea syndrome 2: Effect of treatment on neuropsychiatric morbidity and quality of life
AL‐BARRAK M, SHEPERTYCKY M, KRYGER M. Morbidity and mortality in obstructive sleep apnea syndrome 2: Effect of treatment on neuropsychiatric morbidity and quality of life. Sleep And Biological Rhythms 2003, 1: 65-74. DOI: 10.1046/j.1446-9235.2003.00008.x.Peer-Reviewed Original ResearchContinuous positive airway pressureQuality of lifeNeuropsychiatric problemsObstructive sleep apnea syndrome (OSA) resultsAutomobile accident ratesNocturnal oxygen desaturationPositive airway pressureFragmentation of sleepEffect of treatmentOxygen desaturationAirway pressureOSA patientsResidual abnormalitiesCommon presentationNeuropsychiatric sequelaeNeuropsychiatric morbidityNeuropsychiatric abnormalitiesElectroencephalographic arousalSyndrome 2Syndrome resultsPatientsLife issuesMorbidityOSASAbnormalities
1994
Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure
Steens R, Millar T, Xiaoling S, Biberdorf D, Buckle P, Ahmed M, Kryger M. Effect of Inhaled 3% CO2 on Cheyne-Stokes Respiration in Congestive Heart Failure. Sleep 1994, 17: 61-68. PMID: 8191204, DOI: 10.1093/sleep/17.1.61.Peer-Reviewed Original ResearchConceptsStable congestive heart failureCheyne-Stokes respirationCongestive heart failureInhalation of CO2Heart failureSleep timeNocturnal arterial oxygen desaturationNight polysomnographic studiesArterial oxygen desaturationMovement sleep timeTotal sleep timeApnea indexOxygen desaturationMost patientsPolysomnographic studySleep latencySleep disruptionClinical significanceCardiac diseaseSleep structurePatientsNeurological diseasesNight 3Virtual abolitionShort duration
1993
Nocturnal Cluster Headache Associated with Sleep Apnea. A Case Report
Buckle P, Kerr P, Kryger M. Nocturnal Cluster Headache Associated with Sleep Apnea. A Case Report. Sleep 1993, 16: 487-489. PMID: 8378690, DOI: 10.1093/sleep/16.5.487.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaSleep apneaCluster headacheRapid eye movement (REM) sleepChronic cluster headacheEye movement sleepNasal CPAPOxygen desaturationCase reportMovement sleepHeadache AssociatedBackup rateREM sleepTypical headacheHeadacheApneaSleep labFurther treatmentSleepDesaturationTreatmentBiPAPCPAPMedicationsEffects of Zolpidem and Triazolam on Sleep and Respiration in Mild to Moderate Chronic Obstructive Pulmonary Disease
Steens R, Pouliot Z, Millar T, Kryger M, George C. Effects of Zolpidem and Triazolam on Sleep and Respiration in Mild to Moderate Chronic Obstructive Pulmonary Disease. Sleep 1993, 16: 318-326. PMID: 8341892, DOI: 10.1093/sleep/16.4.318.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseModerate chronic obstructive pulmonary diseaseObstructive pulmonary diseaseEffects of zolpidemPulmonary diseaseDrug conditionsNocturnal arterial oxygen desaturationArterial oxygen desaturationApnea-hypopnea indexGroup of patientsArterial oxygen saturationNumber of awakeningsTotal sleep timeHours of sleepSignificant differencesSubjective sleep variablesNew hypnotic agentOxygen desaturationCrossover studyHypnotic agentsSleep problemsSleep qualityOxygen saturationSleep efficiencyActive drug
1991
Sleep quality in children with asthma treated with theophylline or cromolyn sodium
Avital A, Steljes D, Pasterkamp H, Kryger M, Sanchez I, Chernick V. Sleep quality in children with asthma treated with theophylline or cromolyn sodium. The Journal Of Pediatrics 1991, 119: 979-984. PMID: 1960623, DOI: 10.1016/s0022-3476(05)83062-8.Peer-Reviewed Original ResearchConceptsCromolyn sodiumTheophylline periodPlacebo-controlled trialArterial oxygen desaturationTheophylline blood levelsArterial oxygen saturationTotal sleep timeYears of ageOxygen desaturationPulmonary functionTheophylline treatmentBlood levelsChild's asthmaCentral originSleep latencyProtective effectSleep qualityOxygen saturationSleep efficiencySleep timeAsthmaMicrograms/SleepMovement timeTreatment
1987
Oxygenation and Breathing Pattern During Phasic and Tonic REM in Patients with Chronic Obstructive Pulmonary Disease
George C, West P, Kryger M. Oxygenation and Breathing Pattern During Phasic and Tonic REM in Patients with Chronic Obstructive Pulmonary Disease. Sleep 1987, 10: 234-243. PMID: 3629085, DOI: 10.1093/sleep/10.3.234.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseTonic REMPhasic REMBreathing patternOxygen desaturationPulmonary diseaseSevere chronic obstructive pulmonary diseaseBreathing pattern changesAwake SaO2Nadir SaO2Total REMRespiratory neuronsMore desaturationMotor neuronsOxygen saturationREM sleepSaO2SaO2 differenceTransient decreaseRespiratory amplitudeNight studiesSleepDesaturationPatients
1986
Breathing during Sleep in Normal Pregnant Women1–3
Brownell L, West P, Kryger M. Breathing during Sleep in Normal Pregnant Women1–3. American Journal Of Respiratory And Critical Care Medicine 1986, 133: 38-41. PMID: 3942378, DOI: 10.1164/arrd.1986.133.1.38.Peer-Reviewed Original ResearchConceptsLate pregnancyMinimal arterial oxygen saturationMaternal oxygen desaturationFrequency of apneaRespiratory sleep studiesAlveolar-arterial differenceArterial oxygen saturationFunctional residual capacityLevels of progesteroneSleep-related apneaTotal apneaOxygen desaturationMaternal oxygenationComplete polysomnographyWk gestationPregnant womenCardiac outputLast trimesterPhysiologic changesResidual volumeSupine positionSleep studiesOxygen saturationPregnancyApnea
1982
Sleep, Arousals, and Oxygen Desaturation in Chronic Obstructive Pulmonary Disease
Fleetham J, West P, Mezon B, Conway W, Roth T, Kryger M. Sleep, Arousals, and Oxygen Desaturation in Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 1982, 126: 429-33. PMID: 7125332, DOI: 10.1164/arrd.1982.126.3.429.Peer-Reviewed Original ResearchConceptsOxygen desaturationArousal frequencySleep qualityChronic obstructive pulmonary diseaseAge-matched normal subjectsLower mean SaO2Role of hypoxemiaArterial oxygen desaturationObstructive pulmonary diseaseRoom air breathingArterial O2 saturationPoor sleep qualityReduced sleep timeSleep stage changesApneic episodesPulmonary functionOxygen therapyPulmonary diseaseSupplemental oxygenMean SaO2Sleep disruptionREM sleepNormal subjectsO2 saturationPatients
1980
Sleep Breathing Abnormalities in Kyphoscoliosis1–3
Mezon B, West P, Israels J, Kryger M. Sleep Breathing Abnormalities in Kyphoscoliosis1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 617-21. PMID: 7436128, DOI: 10.1164/arrd.1980.122.4.617.Peer-Reviewed Original ResearchConceptsBreathing abnormalitiesGreater oxygen desaturationPulmonary function testsArterial oxygen saturationCor pulmonaleChronic hypoxemiaOxygen desaturationCentral apneaFunction testsClinical evidencePhysiologic disturbancesSevere kyphoscoliosisMovement sleepSevere derangementThoracic deformityArterial PCO2Oxygen saturationSevere episodesChemical driveAbnormalitiesSleepPatientsDerangementPulmonaleHypoxemiaChemical Control of Ventilation and Sleep Arterial Oxygen Desaturation in Patients with COPD1–3
Fleetham J, Mezon B, West P, Bradley C, Anthonisen N, Kryger M. Chemical Control of Ventilation and Sleep Arterial Oxygen Desaturation in Patients with COPD1–3. American Journal Of Respiratory And Critical Care Medicine 1980, 122: 583-9. PMID: 7436124, DOI: 10.1164/arrd.1980.122.4.583.Peer-Reviewed Original ResearchConceptsO2 saturationSleep desaturationVentilatory sensitivityRapid eye movement (REM) sleepNocturnal changesArterial oxygen desaturationLowest O2 saturationHypoxic ventilatory responseArterial O2 saturationEye movement sleepHypoxemic COPDNocturnal desaturationOxygen desaturationLung functionBlood gasesVentilatory responseMovement sleepVentilatory controlPatientsMaximal desaturationSleepDesaturationSleep stagesHypercapniaWakefulness