1994
Ventilatory Instability in Patients With Congestive Heart Failure and Nocturnal Cheyne-Stokes Breathing
Ahmed M, Serrette C, Kryger M, Anthonisen N. Ventilatory Instability in Patients With Congestive Heart Failure and Nocturnal Cheyne-Stokes Breathing. Sleep 1994, 17: 527-534. PMID: 7809566, DOI: 10.1093/sleep/17.6.527.Peer-Reviewed Original ResearchConceptsCongestive heart failureCheyne-Stokes breathingAir-breathing controlsShort-term potentiationHeart failureCirculatory delayAge-matched normalsEnd-tidal CO2Air-breathing levelsAlveolar hypoxiaCHF patientsHyperoxic ventilationVentilatory instabilityVentilatory patternHypoxic hyperventilationPatient ventilationBreathing controlBreathing patternPatientsHyperoxiaVentilationHypoxiaProlonged circulation timeCompared resultsBrief exposure
1993
Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration
Biberdorf D, Steens R, Millar T, Kryger M. Benzodiazepines in Congestive Heart Failure: Effects of Temazepam on Arousability and Cheyne-Stokes Respiration. Sleep 1993, 16: 529-538. PMID: 8235237, DOI: 10.1093/sleep/16.6.529.Peer-Reviewed Original ResearchConceptsCheyne-Stokes respirationCongestive heart failureTotal sleep timePercentage of TSTApnea/hypopnea indexOxygen saturationTotal wake timeEffects of temazepamHeart failureSleep architectureDouble-blind crossover trialSevere congestive heart failureOvernight oxygen saturationStage 1 sleepHours of sleepSleep stage proportionsCHF patientsHypopnea indexMale patientsDaytime somnolenceCrossover trialSignificant changesFrequent arousalsDaytime alertnessSleep time