2015
Predicting Meaningful Outcomes to Medication and Self-Help Treatments for Binge-Eating Disorder in Primary Care: The Significance of Early Rapid Response
Grilo CM, White MA, Masheb RM, Gueorguieva R. Predicting Meaningful Outcomes to Medication and Self-Help Treatments for Binge-Eating Disorder in Primary Care: The Significance of Early Rapid Response. Journal Of Consulting And Clinical Psychology 2015, 83: 387-394. PMID: 25622201, PMCID: PMC4380674, DOI: 10.1037/a0038635.Peer-Reviewed Original ResearchConceptsBinge-eating disorderSelf-help cognitive behavioral therapyPrimary care settingObese patientsFourth treatment weekBaseline clinical characteristicsBetter clinical outcomesPrimary care physiciansObese patient groupRandomized clinical trialsStrong prognostic indicatorSelf-help interventionEating-disorder psychopathologyImportant clinical implicationsCognitive behavioral therapyAntiobesity medicationsClinical characteristicsMixed-effects model analysisClinical outcomesPercent weight lossPatient groupPrognostic indicatorTreatment weekClinical trialsResearch clinicians
2014
A randomized controlled trial comparing scalable weight loss treatments in primary care
Barnes RD, White MA, Martino S, Grilo CM. A randomized controlled trial comparing scalable weight loss treatments in primary care. Obesity 2014, 22: 2508-2516. PMID: 25298016, PMCID: PMC4236282, DOI: 10.1002/oby.20889.Peer-Reviewed Original ResearchConceptsNutrition psychoeducationUsual careAttention control interventionMotivational interviewingTreatment adherenceWeight lossOverweight/obese patientsBed statusWeight loss outcomesPrimary care settingWeight loss treatmentWeight loss resultsObese patientsTriglyceride levelsPrimary careObesity interventionsNPC patientsLoss outcomesLoss treatmentDepression scoresScalable interventionsPatientsTreatment disseminationSuperior benefitsInterventionTreatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication
Grilo CM, Masheb RM, White MA, Gueorguieva R, Barnes RD, Walsh BT, McKenzie KC, Genao I, Garcia R. Treatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication. Behaviour Research And Therapy 2014, 58: 1-9. PMID: 24857821, PMCID: PMC4074556, DOI: 10.1016/j.brat.2014.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnti-Obesity AgentsBinge-Eating DisorderBlack or African AmericanBody WeightCognitive Behavioral TherapyCombined Modality TherapyCyclobutanesDouble-Blind MethodFemaleHispanic or LatinoHumansMaleMiddle AgedObesityPrimary Health CareSelf CareTime FactorsTreatment OutcomeWhite PeopleYoung AdultConceptsSelf-help cognitive behavioral therapyDiverse obese patientsAnti-obesity medicationsObese patientsModerate clinical outcomePercent weight lossTime interaction effectsWeight lossClinical outcomesPrimary careRandomized placebo-controlled clinical trialSecond placebo-controlled trialPlacebo-controlled clinical trialAcute weight lossPlacebo-controlled trialDouble-blind fashionDiscontinuation of medicationPrimary care settingWeight loss maintenanceSpecialist treatment centresTreatment of bingeDiverse patient groupsSelf-help CBTBinge-eating frequencyDemographic factors
2013
Self-help for binge eating disorder in primary care: A randomized controlled trial with ethnically and racially diverse obese patients
Grilo CM, White MA, Gueorguieva R, Barnes RD, Masheb RM. Self-help for binge eating disorder in primary care: A randomized controlled trial with ethnically and racially diverse obese patients. Behaviour Research And Therapy 2013, 51: 855-861. PMID: 24189569, PMCID: PMC3863907, DOI: 10.1016/j.brat.2013.10.002.Peer-Reviewed Original ResearchConceptsDiverse obese patientsUsual careObese patientsSelf-help CBTPrimary careEating Disorder ExaminationPrimary care interventionsPrimary care settingSelf-help versionFour-month treatmentSelf-help treatmentFront-line interventionCognitive behavioral therapyRemission rateMixed modelsCare interventionsCare settingsPatientsGeneralist settingsBehavioral therapyDisorder ExaminationDisorder psychopathologyWeight lossBingeCareSex differences in biopsychosocial correlates of binge eating disorder: a study of treatment-seeking obese adults in primary care setting
Udo T, McKee SA, White MA, Masheb RM, Barnes RD, Grilo CM. Sex differences in biopsychosocial correlates of binge eating disorder: a study of treatment-seeking obese adults in primary care setting. General Hospital Psychiatry 2013, 35: 587-591. PMID: 23969142, PMCID: PMC3845204, DOI: 10.1016/j.genhosppsych.2013.07.010.Peer-Reviewed Original ResearchConceptsPrimary care settingBiopsychosocial correlatesTreatment-seeking obese patientsPsychosocial factorsSex differencesCare settingsObese menObese adultsClinical studiesFrequent strenuous exercisePsychological impairmentDisorder featuresOnset of overweightCommunity-based studySignificant sex differencesDevelopmental historyTreatment studiesObese patientsBlood pressureMetabolic syndromeBingePrimary careStrenuous exerciseActive screeningGlucose levelsNibbling and picking in obese patients with Binge Eating Disorder
Masheb RM, Roberto CA, White MA. Nibbling and picking in obese patients with Binge Eating Disorder. Eating Behaviors 2013, 14: 424-427. PMID: 24183128, PMCID: PMC3817495, DOI: 10.1016/j.eatbeh.2013.07.001.Peer-Reviewed Original ResearchExamining the relationship between food thought suppression and binge eating disorder
Barnes RD, Masheb RM, White MA, Grilo CM. Examining the relationship between food thought suppression and binge eating disorder. Comprehensive Psychiatry 2013, 54: 1077-1081. PMID: 23751246, PMCID: PMC3779532, DOI: 10.1016/j.comppsych.2013.04.017.Peer-Reviewed Original ResearchSubstantial weight gains are common prior to treatment-seeking in obese patients with binge eating disorder
Masheb RM, White MA, Grilo CM. Substantial weight gains are common prior to treatment-seeking in obese patients with binge eating disorder. Comprehensive Psychiatry 2013, 54: 880-884. PMID: 23639407, PMCID: PMC3779527, DOI: 10.1016/j.comppsych.2013.03.017.Peer-Reviewed Original ResearchConceptsObese patientsBody weightWeight gainWeight gainersWeight lossHigh weight gainersLow weight gainersModest weight lossWeight changePercent of treatmentsFurther weight gainSubstantial weight gainObese BED patientsStabilization of weightTreatment-seeking obese patientsTreatment initiationSelf-report questionnairesBED patientsPatientsWeight trajectoriesCurrent weightTreatment studiesDisorder psychopathologyPercent weight gainMean gainOrlistat with behavioral weight loss for obesity with versus without binge eating disorder: Randomized placebo-controlled trial at a community mental health center serving educationally and economically disadvantaged Latino/as
Grilo CM, White MA. Orlistat with behavioral weight loss for obesity with versus without binge eating disorder: Randomized placebo-controlled trial at a community mental health center serving educationally and economically disadvantaged Latino/as. Behaviour Research And Therapy 2013, 51: 167-175. PMID: 23376451, PMCID: PMC3666334, DOI: 10.1016/j.brat.2013.01.002.Peer-Reviewed Original ResearchConceptsCommunity mental health centerMental health centersPlacebo-controlled trialBehavioral weight lossAddition of orlistatHealth centersRandomized placebo-controlled trialTreatment studiesWeight lossComplex patient groupNon-BED groupObesity Treatment StudyNegative prognostic indicatorHigh rateModerate treatment outcomeRemission rateObese patientsPlacebo medicationDiabetes preventionMixed-model analysisPatient groupObesity treatmentPrognostic indicatorTreatment outcomesEfficacy trials
2012
Predictive significance of the overvaluation of shape/weight in obese patients with binge eating disorder: findings from a randomized controlled trial with 12-month follow-up
Grilo CM, White MA, Gueorguieva R, Wilson GT, Masheb RM. Predictive significance of the overvaluation of shape/weight in obese patients with binge eating disorder: findings from a randomized controlled trial with 12-month follow-up. Psychological Medicine 2012, 43: 1335-1344. PMID: 22967857, PMCID: PMC3666331, DOI: 10.1017/s0033291712002097.Peer-Reviewed Original ResearchConceptsShape/weightCognitive behavioral therapyBehavioral weight lossPoor psychological functioningEating-related psychopathologySelf-esteem levelPsychological functioningDisorder psychopathologyOvervaluation groupBehavioral therapyPsychological distressGroup treatmentFrequent bingeCore featuresSemi-structured interviewsBingeGroup differencesObese patientsTreatment outcomesPredictive significanceLong-term treatment outcomesDiagnostic specifierPsychopathologyGreater levelsNegative prognostic significancePsychiatric disorder co-morbidity and correlates in an ethnically diverse sample of obese patients with binge eating disorder in primary care settings
Grilo CM, White MA, Barnes RD, Masheb RM. Psychiatric disorder co-morbidity and correlates in an ethnically diverse sample of obese patients with binge eating disorder in primary care settings. Comprehensive Psychiatry 2012, 54: 209-216. PMID: 22943959, PMCID: PMC3515704, DOI: 10.1016/j.comppsych.2012.07.012.Peer-Reviewed Original ResearchConceptsGreater eating-disorder psychopathologyCurrent psychiatric disorderEating-disorder psychopathologyPsychiatric disordersObese patientsPrimary careBED patientsDiverse obese patientsCo-morbidity ratesLifetime psychiatric disordersPoor functioningPrimary care settingCaucasian groupSubstance use disordersObese BED patientsConsecutive seriesCare settingsMood disordersGender differencesCurrent diagnosisPatientsAnxiety disordersDisordersBingeHispanic groupsMetabolic syndrome in obese men and women with binge eating disorder: developmental trajectories of eating and weight-related behaviors
Blomquist KK, Milsom VA, Barnes RD, Boeka AG, White MA, Masheb RM, Grilo CM. Metabolic syndrome in obese men and women with binge eating disorder: developmental trajectories of eating and weight-related behaviors. Comprehensive Psychiatry 2012, 53: 1021-1027. PMID: 22483368, PMCID: PMC3394907, DOI: 10.1016/j.comppsych.2012.02.006.Peer-Reviewed Original ResearchConceptsWeight-related behaviorsObese menMetabolic syndromeDevelopmental trajectoriesStructured Clinical InterviewBED onsetObese patientsProspective studyConsecutive seriesExcess weightDistinct developmental trajectoriesVascular symptomsDifferent developmental trajectoriesMetSynMedical diseasesClinical InterviewObesity problemObesitySyndromeLater ageBingeWomenDisordersDemographic variablesMenSignificance of overvaluation of shape and weight in an ethnically diverse sample of obese patients with binge-eating disorder in primary care settings
Grilo CM, White MA, Masheb RM. Significance of overvaluation of shape and weight in an ethnically diverse sample of obese patients with binge-eating disorder in primary care settings. Behaviour Research And Therapy 2012, 50: 298-303. PMID: 22449893, PMCID: PMC3327763, DOI: 10.1016/j.brat.2012.02.008.Peer-Reviewed Original ResearchConceptsBinge-eating disorderShape/weightOvervaluation groupPoor psychological functioningBinge-eating frequencyEating-related psychopathologyDiverse obese patientsGeneral primary care settingsPsychological functioningSignificance of OvervaluationClinical overvaluationDisorder psychopathologyPsychological distressAnxiety disordersCore featuresDiverse samplePrimary care settingDiagnostic specifierPsychopathologyGreater levelsParticipantsOvervaluationEthnicity/raceObese patientsDisorders
2011
Cognitive–Behavioral Therapy, Behavioral Weight Loss, and Sequential Treatment for Obese Patients With Binge-Eating Disorder: A Randomized Controlled Trial
Grilo CM, Masheb RM, Wilson GT, Gueorguieva R, White MA. Cognitive–Behavioral Therapy, Behavioral Weight Loss, and Sequential Treatment for Obese Patients With Binge-Eating Disorder: A Randomized Controlled Trial. Journal Of Consulting And Clinical Psychology 2011, 79: 675-685. PMID: 21859185, PMCID: PMC3258572, DOI: 10.1037/a0025049.Peer-Reviewed Original ResearchConceptsPercent BMI lossBehavioral weight lossBinge-eating disorderCognitive behavioral therapyBMI lossObese patientsWeight lossBinge-eating remissionAlternative treatment optionBinge Eating DisorderRemission rateControlled TrialsTreatment optionsMixed model analysisBehavioral therapyPatientsManualized treatmentAssessment pointsBingeRemissionGreater reductionTreatmentTherapySequential treatmentDisordersRapid response predicts 12-month post-treatment outcomes in binge-eating disorder: theoretical and clinical implications
Grilo CM, White MA, Wilson GT, Gueorguieva R, Masheb RM. Rapid response predicts 12-month post-treatment outcomes in binge-eating disorder: theoretical and clinical implications. Psychological Medicine 2011, 42: 807-817. PMID: 21923964, PMCID: PMC3288595, DOI: 10.1017/s0033291711001875.Peer-Reviewed Original ResearchConceptsBehavioral weight lossBinge-eating disorderCognitive behavioral therapyWeight lossPrognostic significanceClinical implicationsShort-term weight lossDisorder psychopathologyBinge-eating remissionStepped-care modelDifferent prognostic significanceNon-rapid respondersMost baseline variablesPost-treatment outcomesBinge-eating frequencyObese patientsBaseline variablesDistinct time coursesClinical trialsInitial interventionRapid respondersWeek fourBehavioral therapySpecialized treatmentPatientsComparison of methods for identifying and assessing obese patients with binge eating disorder in primary care settings
Barnes RD, Masheb RM, White MA, Grilo CM. Comparison of methods for identifying and assessing obese patients with binge eating disorder in primary care settings. International Journal Of Eating Disorders 2011, 44: 157-163. PMID: 20143322, PMCID: PMC3197249, DOI: 10.1002/eat.20802.Peer-Reviewed Original ResearchConceptsEating Disorder Examination QuestionnaireEating Disorder Examination interviewBody image variablesSelf-report measuresDisorder Examination QuestionnaireHigher scoresWeight Patterns-RevisedBinge eatingEDE interviewExamination interviewExamination QuestionnaireBehavioral indicatorsEDE subscalesBingeImage variablesPrimary care settingQEWPObese patientsEatingEDEPrimary careCare settingsDisordersQuestionnaireInterviews
2010
Physical Activity in Gastric Bypass Patients: Associations with Weight Loss and Psychosocial Functioning at 12-Month Follow-Up
Rosenberger PH, Henderson KE, White MA, Masheb RM, Grilo CM. Physical Activity in Gastric Bypass Patients: Associations with Weight Loss and Psychosocial Functioning at 12-Month Follow-Up. Obesity Surgery 2010, 21: 1564-1569. PMID: 20890771, PMCID: PMC3652016, DOI: 10.1007/s11695-010-0283-z.Peer-Reviewed Original ResearchConceptsGastric bypass patientsBody mass indexPhysical activityBypass patientsWeight lossBetter weight loss outcomesPreoperative body mass indexPsychosocial outcomesPhysical activity episodesGastric bypass surgeryPostoperative weight lossWeight loss outcomesBetter psychosocial outcomesBypass surgeryObese patientsMass indexPostoperative assessmentLoss outcomesBackgroundThis studySelf-reported frequencyPatientsPsychosocial functioningMental healthRegression analysisOutcomesAccuracy of self-reported weight and height and resulting body mass index among obese binge eaters in primary care: relationship with eating disorder and associated psychopathology.
Barnes RD, White MA, Masheb RM, Grilo CM. Accuracy of self-reported weight and height and resulting body mass index among obese binge eaters in primary care: relationship with eating disorder and associated psychopathology. The Primary Care Companion For CNS Disorders 2010, 12 PMID: 21085556, PMCID: PMC2983458, DOI: 10.4088/pcc.09m00868blu.Peer-Reviewed Original ResearchBody mass indexMass indexSelf-reported weightBinge-eating disorderObese patientsDepressive featuresPrimary care clinicsPrimary care settingObese binge eatersEating Disorder Examination interviewBeck Depression InventoryCare clinicsEating Disorder Examination QuestionnairePrimary careCare settingsDepressive symptomsDisorder Examination QuestionnaireBinge eatersDepression InventoryAssociated psychopathologyOverestimation of heightExamination interviewDisorder psychopathologyDisordersExamination Questionnaire
2009
Dieting Frequency in Obese Patients With Binge Eating Disorder: Behavioral and Metabolic Correlates
Roehrig M, Masheb RM, White MA, Grilo CM. Dieting Frequency in Obese Patients With Binge Eating Disorder: Behavioral and Metabolic Correlates. Obesity 2009, 17: 689-697. PMID: 19165172, PMCID: PMC3678720, DOI: 10.1038/oby.2008.600.Peer-Reviewed Original ResearchConceptsTotal/HDL cholesterol ratioHDL cholesterol ratioObese BED patientsObese patientsLipoprotein cholesterolCholesterol ratioFrequent dietersBED patientsHigh-density lipoprotein cholesterolLow-density lipoprotein cholesterolCardiovascular disease riskGreater weight suppressionActual weight statusDisorder pathologyBinge Eating DisorderHDL cholesterolTotal cholesterolMetabolic abnormalitiesWeight cyclingMore episodesWeight statusClinical significanceMetabolic correlatesMetabolic variablesClinical adviceThe Metabolic Syndrome and Behavioral Correlates in Obese Patients With Binge Eating Disorder
Roehrig M, Masheb RM, White MA, Grilo CM. The Metabolic Syndrome and Behavioral Correlates in Obese Patients With Binge Eating Disorder. Obesity 2009, 17: 481-486. PMID: 19219063, PMCID: PMC2704920, DOI: 10.1038/oby.2008.560.Peer-Reviewed Original ResearchConceptsObese patientsMetabolic syndromeMultivariate hierarchical logistic regression analysisRegular meal consumptionWeight loss attemptsLogistic regression analysisObese BED patientsWeight-related correlatesBinge Eating DisorderHierarchical logistic regression analysisLifestyle behaviorsWeight cyclingMetSynBED patientsSelf-reported frequencyMeal skippingPatientsMeal consumptionDemographic featuresBinge eatingDisorder psychopathologyEating DisordersPotential targetSignificant predictorsRegression analysis