E. Leon Kier, MD
Professor Emeritus of Radiology and Biomedical ImagingCards
About
Research
Overview
Medical Research Interests
Anatomy; Embryology; Radiology; Temporal Lobe
Publications
2022
Comparative anatomy of the middle cerebral artery, rhinal and endorhinal sulci, piriform lobe, entorhinal cortex, olfactory tubercule, anterior perforate substance, and hippocampus: A dissection study
Kier E, Conlogue G. Comparative anatomy of the middle cerebral artery, rhinal and endorhinal sulci, piriform lobe, entorhinal cortex, olfactory tubercule, anterior perforate substance, and hippocampus: A dissection study. The Anatomical Record 2022, 306: 2030-2043. PMID: 36371781, DOI: 10.1002/ar.25124.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryRecurrent arteryPiriform lobeHuman fetal specimensOlfactory tuberculeLenticulostriate arteriesRhinal sulcusEndorhinal sulcusCerebral arteryTemporal lobeFetal specimensAnatomic modificationsHuman temporal lobeStriate nucleusMCA branchesArteryInferomedial regionHeubnerHippocampusComplex anatomyDissection studiesBrain dissectionCerebrumSulcusLobeCerebral arterial and ventricular morphology of the dogfish (Squalus acanthias), American bullfrog (Rana catesbeiana), and green iguana (Iguana iguana): Arterial high‐resolution micro‐CT, dissection, and radiography study
Kier E, Conlogue G, VanHouten J. Cerebral arterial and ventricular morphology of the dogfish (Squalus acanthias), American bullfrog (Rana catesbeiana), and green iguana (Iguana iguana): Arterial high‐resolution micro‐CT, dissection, and radiography study. The Anatomical Record 2022, 306: 2015-2029. PMID: 35778853, DOI: 10.1002/ar.25028.Peer-Reviewed Original ResearchConceptsMicro-CT imagesHigh-resolution micro-CTMicro-CTMicro-computed tomography (CT) imagingMicro-CT imagingArterial morphologyVenous cerebral circulationSequential displayGreen iguanasCerebral circulationVentricular morphologyRadiopaque contrastArterial circulationCorrosionArterial branchesVentricular systemRadiography studiesMorphologyArterial segmentsArterial structureAnatomic informationTomography imagingBrainArterial capillariesArterial network
2021
Comparative anatomy of dissected optic lobes, optic ventricles, midbrain tectum, collicular ventricles, and aqueduct: evolutionary modifications as potential explanation for non-tumoral aqueductal anomalies in humans
Kier E, Kalra V, Conlogue G, Filippi C, Saluja S. Comparative anatomy of dissected optic lobes, optic ventricles, midbrain tectum, collicular ventricles, and aqueduct: evolutionary modifications as potential explanation for non-tumoral aqueductal anomalies in humans. Child's Nervous System 2021, 38: 287-294. PMID: 34812897, PMCID: PMC8789712, DOI: 10.1007/s00381-021-05408-0.Peer-Reviewed Original ResearchConceptsEvolutionary modificationsVertebrate materialMammalian componentsTectum structuresAdult sharksNeocortical expansionVertebratesComparative anatomyOptic lobeRelative size changesContinuous cavityOptic ventricleMammalsSharksSize changesFrogsIguanasOccipital lobeModificationMidbrain tectumMidbrain tectum structuresTectumPotential explanationAqueductal stenosisCerebral ventricle
2019
High‐Resolution Computed Tomography Imaging of the Cranial Arterial System and Rete Mirabile of the Cat (Felis catus)
Kier EL, Conlogue GJ, Zhuang Z. High‐Resolution Computed Tomography Imaging of the Cranial Arterial System and Rete Mirabile of the Cat (Felis catus). The Anatomical Record 2019, 302: 1958-1967. PMID: 31502384, PMCID: PMC6856801, DOI: 10.1002/ar.24251.Peer-Reviewed Original ResearchConceptsArterial circulationCranial circulationArterial systemHigh-resolution CT studiesPlain radiographic studiesRete mirabileHigh-resolution multiplanarRadiographic studiesCT studiesVascular anatomyMultiplanar reconstructionPlane angulationDisruption of tissueBony anatomyTomography imagingIntact skullCatsBone componentsRadiographic techniquesContrast compoundVascular visualization
2004
MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer's loop of the optic radiation.
Kier EL, Staib LH, Davis LM, Bronen RA. MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer's loop of the optic radiation. American Journal Of Neuroradiology 2004, 25: 677-91. PMID: 15140705, PMCID: PMC7974480.Peer-Reviewed Original ResearchConceptsInferior occipitofrontal fasciculusTemporal stemMeyer's loopOccipitofrontal fasciculusUncinate fasciculusMR anatomyOptic radiationExtreme capsuleTemporal lobeLateral geniculate bodyAnterior temporal lobeCross-sectional MR imagesPostoperative complicationsTumor spreadExternal capsuleGeniculate bodyAnterior commissureAnatomic foundationAnatomic featuresBrain disordersAlzheimer's diseaseMR imagingDiffusion tractographyFasciculusTractAnatomic dissection tractography: a new method for precise MR localization of white matter tracts.
Kier EL, Staib LH, Davis LM, Bronen RA. Anatomic dissection tractography: a new method for precise MR localization of white matter tracts. American Journal Of Neuroradiology 2004, 25: 670-6. PMID: 15140704, PMCID: PMC7974503.Peer-Reviewed Original Research
2000
MR Imaging and Histologic Features of Subinsular Bright Spots on T2-weighted MR Images: Virchow-Robin Spaces of the Extreme Capsule and Insular Cortex
Song C, Kim J, Kier E, Bronen R. MR Imaging and Histologic Features of Subinsular Bright Spots on T2-weighted MR Images: Virchow-Robin Spaces of the Extreme Capsule and Insular Cortex. Radiology 2000, 214: 671-677. PMID: 10715028, DOI: 10.1148/radiology.214.3.r00mr17671.Peer-Reviewed Original ResearchConceptsInsular cortexExtreme capsuleMR imagingControl subjectsBrain specimensPerivascular spacesFormalin-fixed brain specimensFluid-attenuated inversion recovery sequencesVirchow-Robin spacesT2-weighted magnetic resonance imagesCoronal T2-weighted imagesT2-weighted imagesCoronal MR imagesHigh signal intensityT2-weighted MR imagesInversion recovery sequenceHistologic featuresHistologic findingsCerebrospinal fluidMR imagesPatientsWhite matterPathologic conditionsGross anatomic inspectionMagnetic resonance images
1997
The lamina rostralis: modification of concepts concerning the anatomy, embryology, and MR appearance of the rostrum of the corpus callosum.
Kier EL, Truwit CL. The lamina rostralis: modification of concepts concerning the anatomy, embryology, and MR appearance of the rostrum of the corpus callosum. American Journal Of Neuroradiology 1997, 18: 715-22. PMID: 9127036, PMCID: PMC8338510.Peer-Reviewed Original Research
1996
The normal and abnormal genu of the corpus callosum: an evolutionary, embryologic, anatomic, and MR analysis.
Kier E, Truwit C. The normal and abnormal genu of the corpus callosum: an evolutionary, embryologic, anatomic, and MR analysis. American Journal Of Neuroradiology 1996, 17: 1631-41. PMID: 8896613, PMCID: PMC8338282.Peer-Reviewed Original ResearchConceptsCorpus callosumCallosal anomaliesHuman corpus callosumAdult mammal brainHuman fetal brainHuman fetal developmentFrontal lobe sizeMR imagesMamillary bodiesAnterior commissureFetal brainCallosumFetal developmentAbnormal appearanceGenuNormal corpusPatientsMR analysisAnterior bodyMammal brainBrainCommissure
1993
Unilateral Transplantation of Human Fetal Mesencephalic Tissue Into the Caudate Nucleus of Patients With Parkinson's Disease
SPENCER D, ROBBINS R, NAFTOLIN F, MAREK K, VOLLMER T, LERANTH C, ROTH R, PRICE L, GJEDDE A, BUNNEY B, SASS K, ELSWORTH J, KIER E, MAKUCH R, HOFFER P, REDMOND D. Unilateral Transplantation of Human Fetal Mesencephalic Tissue Into the Caudate Nucleus of Patients With Parkinson's Disease. Obstetrical & Gynecological Survey 1993, 48: 413-415. DOI: 10.1097/00006254-199306000-00013.Peer-Reviewed Original Research
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