2023
A New Solution to an Age-old Problem: A Review of Ketamine and Esketamine for Treatment-resistant Depression in Late Life
Balaram K, van Dyck L, Wilkins K, Maruca-Sullivan P. A New Solution to an Age-old Problem: A Review of Ketamine and Esketamine for Treatment-resistant Depression in Late Life. Current Geriatrics Reports 2023, 12: 93-102. DOI: 10.1007/s13670-023-00389-1.Peer-Reviewed Original ResearchTreatment-resistant major depressive disorderUse of ketamineOlder adultsKetamine/esketamineTreatment-resistant depressionAnti-depressant effectsEfficacy of ketamineLate-onset depressionOnset of actionCurrent treatment strategiesLate-life depressionCase series dataMajor depressive disorderTypes of patientsDegree of disabilityPotential long termOpen labelAntidepressant effectsOnset depressionOverall mortalityHealthcare utilizationTreatment algorithmCase reportCaregiver burdenClinical trials
2017
Pharmacology of Geriatric Substance Use Disorders: Considerations and Future Directions
Hassell C, Wilkins K, Trevisan L. Pharmacology of Geriatric Substance Use Disorders: Considerations and Future Directions. Current Treatment Options In Psychiatry 2017, 4: 102-115. DOI: 10.1007/s40501-017-0107-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSubstance use disordersEvidence-based treatmentsUse disordersGeriatric populationEvidence-based pharmacological treatment optionsAvailable evidence-based treatmentsHigh-quality clinical trialsOlder adultsAvailable pharmacological treatmentsPharmacological treatment optionsLimitations of treatmentPharmacological treatmentTreatment optionsClinical trialsCertain drugsYoung adultsAdverse effectsDisordersTreatmentAdultsHigh rateUnique needsPopulationBaby boomer generationDysfunction