2019
High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans.
Banerjee G, Edelman EJ, Barry DT, Crystal S, Gordon KS, Gordon AJ, Gaither JR, Green TC, Kerns RD, Manhapra A, Moore BA, Fiellin DA, Marshall BDL. High-dose prescribed opioids are associated with increased risk of heroin use among United States military veterans. Pain 2019, 160: 2126-2135. PMID: 31145217, PMCID: PMC6699915, DOI: 10.1097/j.pain.0000000000001606.Peer-Reviewed Original ResearchConceptsHigh-dose opioid prescriptionsOpioid prescriptionsHeroin useCohort studyPrior receiptHepatitis C virus (HCV) infection statusLong-term opioid prescriptionsPast-year heroin useVeterans Aging Cohort StudyHigh-dose opioidsOpioid-prescribing patternsProspective cohort studyAging Cohort StudyOpioid use disorderCurrent national guidelinesUnhealthy alcohol useUnited States veteransUnited States military veteransVirus infection statusPosttraumatic stress disorderOpioid receiptPrescribed opioidsPain interferenceCox regressionStates veterans
2018
Duration of opioid prescriptions predicts incident nonmedical use of prescription opioids among U.S. veterans receiving medical care
Barry DT, Marshall BDL, Becker WC, Gordon AJ, Crystal S, Kerns RD, Gaither JR, Gordon KS, Justice AC, Fiellin DA, Edelman EJ. Duration of opioid prescriptions predicts incident nonmedical use of prescription opioids among U.S. veterans receiving medical care. Drug And Alcohol Dependence 2018, 191: 348-354. PMID: 30176548, PMCID: PMC6596307, DOI: 10.1016/j.drugalcdep.2018.07.008.Peer-Reviewed Original ResearchConceptsPrescription opioid receiptPrescription opioidsMedical careOpioid receiptVeterans Health Administration primary careNonmedical useMultivariable Cox modelInfectious disease clinicProspective cohort studyProportional hazards regressionPrescription opioid medicationsPublic health problemSubstance use disordersMedication-related characteristicsOpioid therapyOpioid medicationsOpioid prescriptionsCohort studyDisease clinicMedian ageHazards regressionEligible participantsPrimary careRisk factorsIncidence rate
2017
Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men
Adams JW, Bryant KJ, Edelman J, Fiellin DA, Gaither JR, Gordon AJ, Gordon KS, Kraemer KL, Mimiaga MJ, Operario D, Tate JP, van den Berg JJ, Justice AC, Marshall BDL. Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men. AIDS And Behavior 2017, 22: 1341-1351. PMID: 28887669, PMCID: PMC5881942, DOI: 10.1007/s10461-017-1905-4.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyLow-risk alcohol useRisk alcohol useMortality riskAlcohol useStimulant useAdjusted longitudinal analysesAging Cohort StudyUnhealthy alcohol useAssociation of cannabisVACS IndexCause mortalityCohort studyPatient populationPrognostic indicatorMortality prognosisHIVStudy periodSubstance useCannabisRiskLongitudinal analysisMenMortalityStimulants
2016
Immunological and infectious risk factors for lung cancer in US veterans with HIV: a longitudinal cohort study
Sigel K, Wisnivesky J, Crothers K, Gordon K, Brown ST, Rimland D, Rodriguez-Barradas MC, Gibert C, Goetz MB, Bedimo R, Park LS, Dubrow R. Immunological and infectious risk factors for lung cancer in US veterans with HIV: a longitudinal cohort study. The Lancet HIV 2016, 4: e67-e73. PMID: 27916584, PMCID: PMC5444465, DOI: 10.1016/s2352-3018(16)30215-6.Peer-Reviewed Original ResearchConceptsCD4/CD8 ratioBacterial pneumonia episodesLung cancerCD8 ratioPneumonia episodesCohort studyHIV infectionUse disordersCumulative exposureLower CD4/CD8 ratioLow CD4 cell countsHepatitis C virus infectionVeterans Aging Cohort StudyChronic obstructive pulmonary diseaseAntiretroviral therapy eraAverage cumulative exposureDysfunctional immune activationHIV RNA concentrationIncident lung cancerLarge HIV cohortC virus infectionCD4 cell countObstructive pulmonary diseaseAging Cohort StudyInfectious risk factorsThe impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy
Edelman E, Gordon K, Tate J, Becker W, Bryant K, Crothers K, Gaither, Gibert C, Gordon A, Marshall B, Rodriguez‐Barradas M, Samet J, Skanderson M, Justice A, Fiellin D. The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy. HIV Medicine 2016, 17: 728-739. PMID: 27186715, PMCID: PMC5053822, DOI: 10.1111/hiv.12377.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidAnti-Retroviral AgentsCD4 Lymphocyte CountFemaleHIV InfectionsHumansImmunosuppressive AgentsLongitudinal StudiesMaleMiddle AgedConceptsCD4 cell countBaseline CD4 cell countCell countPrescribed opioidsImmunosuppressive propertiesVeterans Aging Cohort Study (VACS) dataCD4 cell count recoveryAntiretroviral therapy responseCell count recoveryShort-term opioidsViral load suppressionCohort study dataOverall disease severityYear of initiationPrimary independent variableOpioid durationAntiretroviral therapyCount recoveryComorbid conditionsPharmacy dataOpioid propertiesTherapy responseOpioidsPatientsHIVComparative Effectiveness of Diabetic Oral Medications Among HIV-Infected and HIV-Uninfected Veterans
Han JH, Gordon K, Womack JA, Gibert CL, Leaf DA, Rimland D, Rodriguez-Barradas MC, Bisson GP. Comparative Effectiveness of Diabetic Oral Medications Among HIV-Infected and HIV-Uninfected Veterans. Diabetes Care 2016, 40: 218-225. PMID: 27634393, PMCID: PMC5250696, DOI: 10.2337/dc16-0718.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack or African AmericanBlood GlucoseBody Mass IndexComparative Effectiveness ResearchDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinHispanic or LatinoHIV InfectionsHumansHypoglycemic AgentsLongitudinal StudiesMaleMetforminMiddle AgedSulfonylurea CompoundsThiazolidinedionesVeteransWhite PeopleConceptsType 2 diabetesDiabetic medicationsHIV infectionHispanic patientsPoor responseGlycemic responseOral diabetic medicationsLongitudinal cohort studyBaseline HbAGlycemic effectivenessHIV-InfectedUninfected veteransMedication initiationCohort studyOral medicationsWhite patientsPotential confoundersClinical covariatesMedicationsHIVPatientsType 2Comparative effectivenessPropensity scoreDiabetes
2014
Sexual Partner Notification of HIV Infection Among a National United States-Based Sample of HIV-Infected Men
Edelman EJ, Gordon KS, Hogben M, Crystal S, Bryant K, Justice AC, Fiellin DA, for the VACS Project Team. Sexual Partner Notification of HIV Infection Among a National United States-Based Sample of HIV-Infected Men. AIDS And Behavior 2014, 18: 1898-1903. PMID: 24858394, PMCID: PMC4195536, DOI: 10.1007/s10461-014-0799-7.Peer-Reviewed Original Research