2018
Nonantiretroviral polypharmacy and adverse health outcomes among HIV-infected and uninfected individuals
Justice AC, Gordon KS, Skanderson M, Edelman EJ, Akgün KM, Gibert CL, Re V, Rimland D, Womack JA, Wyatt CM, Tate JP, Team V. Nonantiretroviral polypharmacy and adverse health outcomes among HIV-infected and uninfected individuals. AIDS 2018, 32: 739-749. PMID: 29543653, PMCID: PMC5868488, DOI: 10.1097/qad.0000000000001756.Peer-Reviewed Original ResearchConceptsAdverse health outcomesHIV statusUninfected individualsVACS IndexMedication countUS Veterans Affairs Healthcare SystemHealth outcomesVeterans Affairs Healthcare SystemRisk of hospitalizationSeverity of illnessHIV-1 RNAHIV-positive individualsRisk of mortalityDose responseRace/ethnicityPolypharmacyFiscal year 2009HospitalizationMedicationsMortalityHealthcare systemAntiretroviralsOutcomesAssociationRisk
2012
Comorbid Diabetes and the Risk of Progressive Chronic Kidney Disease in HIV-Infected Adults
Medapalli RK, Parikh CR, Gordon K, Brown ST, Butt AA, Gibert CL, Rimland D, Rodriguez-Barradas MC, Chang CC, Justice AC, He JC, Wyatt CM. Comorbid Diabetes and the Risk of Progressive Chronic Kidney Disease in HIV-Infected Adults. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2012, 60: 393-399. PMID: 22592587, PMCID: PMC3392432, DOI: 10.1097/qai.0b013e31825b70d9.Peer-Reviewed Original ResearchConceptsCKD risk factorsTraditional CKD risk factorsRisk factorsBaseline eGFRChronic kidney disease progressionProgressive chronic kidney diseaseChronic kidney diseaseKidney disease progressionGlomerular filtration rateMean baseline eGFRRisk of CKDRate of progressionCox proportional hazardsVeterans Healthcare AdministrationUse of cARTBaseline HIVCKD progressionComorbid diabetesAdjunctive therapyDiabetes statusGlycemic controlKidney diseaseProgressive CKDComplex comorbiditiesFiltration rateHIV as an independent risk factor for incident lung cancer
Sigel K, Wisnivesky J, Gordon K, Dubrow R, Justice A, Brown ST, Goulet J, Butt AA, Crystal S, Rimland D, Rodriguez-Barradas M, Gibert C, Park LS, Crothers K. HIV as an independent risk factor for incident lung cancer. AIDS 2012, 26: 1017-1025. PMID: 22382152, PMCID: PMC3580210, DOI: 10.1097/qad.0b013e328352d1ad.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosIndependent risk factorUninfected patientsLung cancerSimilar HIVHIV infectionSurveillance biasRisk factorsIncidence rateVeterans Aging Cohort Study Virtual CohortVeterans Affairs Central Cancer RegistryChronic obstructive pulmonary diseaseIncident lung cancerObstructive pulmonary diseaseCentral Cancer RegistryLung cancer stageSimilar stage distributionRace/ethnicityExcess smokingMultivariable adjustmentAnalytic cohortPulmonary diseaseBacterial pneumoniaCancer RegistryPotential confounders
2010
Hepatitis C and the Risk of Kidney Disease and Mortality in Veterans With HIV
Fischer MJ, Wyatt CM, Gordon K, Gibert CL, Brown ST, Rimland D, Rodriguez-Barradas MC, Justice AC, Parikh CR. Hepatitis C and the Risk of Kidney Disease and Mortality in Veterans With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2010, 53: 222-226. PMID: 20104121, PMCID: PMC3032564, DOI: 10.1097/qai.0b013e3181b980d4.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseHepatitis C virusKidney diseaseMortality rateGlomerular filtration rateAdjusted mortality rateLevels of eGFRVeterans Healthcare AdministrationHepatitis CCoinfected subjectsC virusFiltration rateNational cohortIndependent associationHIVHigh mortalityPoisson regressionMortalityGraduated increaseVeteransCohortHigh rateEGFRDiseaseHealthcare administration