2020
Yttrium-90 Radioembolization for BCLC Stage C Hepatocellular Carcinoma Comparing Child–Pugh A Versus B7 Patients: Are the Outcomes Equivalent?
Zu Q, Schenning RC, Jahangiri Y, Tomozawa Y, Kolbeck KJ, Kaufman JA, Al-Hakim R, Naugler WE, Nabavizadeh N, Kardosh A, Billingsley KG, Mayo SC, Orloff SL, Enestvedt KK, Maynard E, Ahn J, Lhewa D, Farsad K. Yttrium-90 Radioembolization for BCLC Stage C Hepatocellular Carcinoma Comparing Child–Pugh A Versus B7 Patients: Are the Outcomes Equivalent? CardioVascular And Interventional Radiology 2020, 43: 721-731. PMID: 32140840, DOI: 10.1007/s00270-020-02434-4.Peer-Reviewed Original ResearchConceptsC hepatocellular carcinomaChild-Pugh AAdvanced hepatocellular carcinomaOverall survivalHepatocellular carcinomaBCLC stage C hepatocellular carcinomaEastern Cooperative Oncology Group scoreBCLC-C hepatocellular carcinomasMultivariable Cox regression analysisChild-Pugh scoreMedian overall survivalChild-Pugh classKaplan-Meier methodCox regression analysisYttrium-90 RadioembolizationLog-rank testCautious patient selectionSignificant independent predictorsChild-PughHCV infectionResultsMean ageY90 radioembolizationAdditional malignanciesConsecutive patientsIndependent predictors
2018
Tailored treatment of patients with hepatocellular carcinoma with portal vein invasion: experience from a multidisciplinary hepatobiliary tumor program within a NCI comprehensive cancer center
Walcott-Sapp S, Naugler S, Lim JY, Wagner J, Orloff SL, Farsad K, Kolbeck KJ, Kaufman J, Maynard E, Enestvedt CK, Mayo SC, Billingsley KG. Tailored treatment of patients with hepatocellular carcinoma with portal vein invasion: experience from a multidisciplinary hepatobiliary tumor program within a NCI comprehensive cancer center. Journal Of Gastrointestinal Oncology 2018, 9: 1074-1083. PMID: 30603126, PMCID: PMC6286927, DOI: 10.21037/jgo.2018.08.11.Peer-Reviewed Original ResearchPortal vein invasionLiver-directed therapiesIntra-arterial brachytherapyHepatocellular carcinomaTransarterial chemoembolizationVein invasionInitial HCC diagnosisLiver-directed treatmentsMean Child-TurcotteMedian alkaline phosphataseSupportive care groupLimited treatment optionsTreatment of patientsKaplan-Meier plotsComprehensive cancer centerLog-rank methodPalliative chemotherapyChild-TurcottePugh scoreLiver dysfunctionLiver involvementVenous involvementConsecutive patientsMost patientsOverall survival
2017
A propensity matched survival analysis comparing treatment strategies for stage B and C hepatocellular carcinoma
Castillo A, Parreco J, Naugler W, Kolbeck K, Farsad K, Orloff S, Billingsley K, Enestvedt C. A propensity matched survival analysis comparing treatment strategies for stage B and C hepatocellular carcinoma. Hepato Pancreato Biliary 2017, 19: s105-s106. DOI: 10.1016/j.hpb.2017.02.156.Peer-Reviewed Original Research
2011
Stereotactic Body Radiation Therapy (SBRT) for Hepatocellular Carcinoma (HCC): Rationale and Preliminary Data Supporting Hypothesis-driven Prospective Clinical Trial Development
Fuss M, Schwartz J, Naugler W, Urquhart J, Orloff S, Billingsley K, Vaccaro G, Koslin B, Kolbeck K, Kaufman J. Stereotactic Body Radiation Therapy (SBRT) for Hepatocellular Carcinoma (HCC): Rationale and Preliminary Data Supporting Hypothesis-driven Prospective Clinical Trial Development. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: s170. DOI: 10.1016/j.ijrobp.2011.06.1677.Peer-Reviewed Original Research