2017
Systems analysis of latent HIV reversal reveals altered stress kinase signaling and increased cell death in infected T cells
Fong LE, Sulistijo ES, Miller-Jensen K. Systems analysis of latent HIV reversal reveals altered stress kinase signaling and increased cell death in infected T cells. Scientific Reports 2017, 7: 16179. PMID: 29170390, PMCID: PMC5701066, DOI: 10.1038/s41598-017-15532-0.Peer-Reviewed Original ResearchConceptsInfected T cellsT cellsT cell reservoirCell deathPMA/ionomycinCD3/CD28Phosphorylation of IκBαViral protein expressionPhosphorylation signaturesHIV eradicationLatent CD4HIV reactivationLatent reservoirLatent HIVActivation of p38Latent infectionClinical strategiesViral latencyViral expressionProtein expressionUninfected cellsInfected cellsDeathCD4Cell reservoir
2015
Assessing Host Immune Response to Dengue Virus Infection at Single‐Cell Resolution
Sulistijo E, Miller‐Jensen K. Assessing Host Immune Response to Dengue Virus Infection at Single‐Cell Resolution. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.571.26.Peer-Reviewed Original ResearchDengue shock syndromeDENV infectionDengue hemorrhagic feverDengue virusImmune responseDHF/dengue shock syndromeDengue feverSevere dengue hemorrhagic feverLevels of cytokinesDengue virus infectionInfected cellsSignaling profilesImmune cell responsesHost immune responseHost immune systemMosquito-borne pathogenNon-infected cellsInflammatory cytokinesShock syndromeDisease progressionVirus infectionHemorrhagic feverTherapeutic targetImmune systemSuppress progression