About
Titles
Staff Affiliate - VAMC
Departments & Organizations
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Kathleen McGinnis's published research.
E. Jennifer Edelman, MD, MHS, BS
Lamia Y. K. Haque, MD, MPH
David Fiellin, MD
Evelyn Hsieh, MD, PhD
Jeanette Tetrault, MD, FACP, FASAM
Kirsha Gordon, PhD, MS
Publications
2024
Using Phosphatidylethanol as an Adjunct to Self-Reported Alcohol Use Improves Identification of Liver Fibrosis Risk.
Murnane P, Afshar M, Chamie G, Cook R, Ferguson T, Haque L, Jacobson K, Justice A, Kim T, Khalili M, Krupitsky E, McGinnis K, Molina P, Muyindike W, Myers B, Richards V, So-Armah K, Stewart S, Sulkowski M, Tien P, Hahn J. Using Phosphatidylethanol as an Adjunct to Self-Reported Alcohol Use Improves Identification of Liver Fibrosis Risk. The American Journal Of Gastroenterology 2024 PMID: 39480054, DOI: 10.14309/ajg.0000000000003178.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLiver fibrosis riskAUDIT-CFIB-4Self-reported alcohol useOdds ratioAlcohol useFibrosis riskPooled individual-level dataLiver fibrosis preventionBody mass indexAssessment of alcohol useManagement of liver diseaseOne-unit differenceIndividual-level dataMedian ageAUDIT-C.Mass indexSuppression statusLiver diseaseFibrosis preventionBlood concentrationsAdjusted modelsLogistic regressionCategorical variablesHIVPain, Substance Use Disorders, Mental Health, and Buprenorphine Treatment among Patients With and Without HIV
Miller E, McGinnis K, Edelman E, Feinberg T, Gordon K, Kerns R, Marshall B, Patterson J, McRae M. Pain, Substance Use Disorders, Mental Health, and Buprenorphine Treatment among Patients With and Without HIV. AIDS And Behavior 2024, 28: 3994-4004. PMID: 39264485, PMCID: PMC11586311, DOI: 10.1007/s10461-024-04494-w.Peer-Reviewed Original ResearchAltmetricConceptsMental health classesSubstance use disordersOpioid use disorderHIV statusBuprenorphine initiationVeterans Aging Cohort StudyInitiate buprenorphineMental health diagnosesAging Cohort StudyBuprenorphine treatmentMultiple pain conditionsAssociated with HIV statusInfluence treatment retentionUse disorderTreatment of opioid use disorderHigher comorbidity burdenAge of patientsClinical encountersMental healthHealth diagnosisBlack veteransHealth classesLatent class analysisCohort studyPrescription dataEvaluation of mean corpuscular volume among anemic people with HIV in North America following ART initiation
Lang R, Coburn S, Gill M, Justice A, Grossman J, Gebo K, Horberg M, Mayor A, Silverberg M, McGinnis K, Hogan B, Moore R, Althoff K. Evaluation of mean corpuscular volume among anemic people with HIV in North America following ART initiation. AIDS Research And Therapy 2024, 21: 52. PMID: 39113038, PMCID: PMC11304803, DOI: 10.1186/s12981-024-00641-4.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsAntiretroviral therapy initiationAntiretroviral therapyNormocytic anemiaMicrocytic anemiaMean corpuscular volumeRisk factorsMacrocytic anemiaAssociated with increased morbidityCausative factors of anemiaProportion of PWHFactors of anemiaAssociated with increasing ageClassification of anemiaIdentified risk factorsAnemic peopleCD4 countHIV factorsNA-ACCORDLow hemoglobinAnemiaPWHEstimate crudeRobust varianceHemoglobin measurementsHIVCOVID-19 Breakthrough Infection after Vaccination and Substance Use Disorders: A Longitudinal Cohort of People with and without HIV Receiving Care in the United States Veterans Health Administration
Soyer E, McGinnis K, Justice A, Hsieh E, Rodriguez-Barradas M, Williams E, Park L. COVID-19 Breakthrough Infection after Vaccination and Substance Use Disorders: A Longitudinal Cohort of People with and without HIV Receiving Care in the United States Veterans Health Administration. AIDS And Behavior 2024, 28: 3605-3614. PMID: 39046612, DOI: 10.1007/s10461-024-04449-1.Peer-Reviewed Original ResearchAltmetricConceptsHIV statusSubstance use disordersBreakthrough infectionRisk of breakthroughAssociated with increased riskCOVID-19 breakthrough infectionsSARS-CoV-2Association of substance useSARS-CoV-2 infectionHIV treatment adherenceCD4 countHIV progressionSubstance useUnited States Veterans Health AdministrationHazard ratioIncreased riskPWHCD4PWoHHIVUse disorderVaccinated personsCohort of peopleTreatment adherenceLongitudinal cohortW31 The Impact of Tobacco Use on Liver-Related Morbidity in Patients With Cirrhosis
Haque L, Fiellin D, Bryant K, Edelman E, Justice A, Lim J, Re V, Marshall B, Taddei T, Tate J, Tetrault J, Williams E, McGinnis K. W31 The Impact of Tobacco Use on Liver-Related Morbidity in Patients With Cirrhosis. Drug And Alcohol Dependence 2024, 260: 110649. DOI: 10.1016/j.drugalcdep.2023.110649.Peer-Reviewed Original ResearchDiscrimination of the Veterans Aging Cohort Study Index 2.0 for Predicting Cause-specific Mortality Among Persons With HIV in Europe and North America
Ambia J, Ingle S, McGinnis K, Pantazis N, Silverberg M, Wittkop L, Kusejko K, Crane H, van Sighem A, Sarcletti M, Cozzi-Lepri A, Domingo P, Jarrin I, Wyen C, Hessamfar M, Zhang L, Cavassini M, Berenguer J, Sterling T, Reiss P, Abgrall S, Gill M, Justice A, Sterne J, Trickey A. Discrimination of the Veterans Aging Cohort Study Index 2.0 for Predicting Cause-specific Mortality Among Persons With HIV in Europe and North America. Open Forum Infectious Diseases 2024, 11: ofae333. PMID: 39015347, PMCID: PMC11249920, DOI: 10.1093/ofid/ofae333.Peer-Reviewed Original ResearchAltmetricConceptsVeterans Aging Cohort StudyVeterans Aging Cohort Study IndexCause-specific mortalityNon-AIDS-defining cancersNon-AIDS-definingPredicting cause-specific mortalityFlexible parametric survival modelsAntiretroviral therapyC-statisticNon-AIDS infectionsAging Cohort StudyAbsolute mortality riskHarrell's C-statisticAntiretroviral therapy initiationParametric survival modelsTargeted careCause of deathMortality riskVisit dateMultiple imputationCohort studyPWHAssess discriminationCox modelRespiratory-relatedIncidence of non-AIDS defining comorbidities among young adults with perinatally acquired HIV in North America
Haw N, Lesko C, Ng D, Lam J, Lang R, Kitahata M, Crane H, Eron J, Gill M, Horberg M, Karris M, Loutfy M, McGinnis K, Moore R, Althoff K, Agwu A. Incidence of non-AIDS defining comorbidities among young adults with perinatally acquired HIV in North America. AIDS 2024, 38: 1366-1374. PMID: 38507583, PMCID: PMC11211058, DOI: 10.1097/qad.0000000000003892.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPerinatally-acquired HIVChronic kidney diseaseMedication useIncidence rateNorth American AIDS Cohort CollaborationElectronic health recordsRoutine HIV careCumulative incidenceResearch and DesignIncidence of diabetes mellitus type 2Young adultsQuasi-Poisson regressionNon-Black femalesDescription of outcomesGlycosylated haemoglobin >Clinical diagnosisHIV careHealth recordsNA-ACCORDBlack adultsIncidence of hypercholesterolemiaDiabetes mellitus type 2Hypertension incidenceCKD incidenceAmerican adultsCombining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration
McGinnis K, Justice A, Marconi V, Rodriguez-Barradas M, Hauser R, Oursler K, Brown S, Bryant K, Tate J, Study F. Combining Charlson comorbidity and VACS indices improves prognostic accuracy for all-cause mortality for patients with and without HIV in the Veterans Health Administration. Frontiers In Medicine 2024, 10: 1342466. PMID: 38356736, PMCID: PMC10864663, DOI: 10.3389/fmed.2023.1342466.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCharlson Comorbidity IndexVACS IndexHIV RNAVeterans Health AdministrationComorbid diseasesNon-AIDS conditionsCongestive heart failureAssociated with CD4Risk of mortalityMedian ageHepatitis C.Older age groupsCharlson comorbidityCD4Prognostic accuracyHeart failurePWoHComorbidity indexVA careKidney diseasePWHHIVMatched comparatorsBaseline predictorsClinical biomarkersLongitudinal trends in causes of death among adults with HIV on antiretroviral therapy in Europe and North America from 1996 to 2020: a collaboration of cohort studies
Trickey A, McGinnis K, Gill M, Abgrall S, Berenguer J, Wyen C, Hessamfar M, Reiss P, Kusejko K, Silverberg M, Imaz A, Teira R, d'Arminio Monforte A, Zangerle R, Guest J, Papastamopoulos V, Crane H, Sterling T, Grabar S, Ingle S, Sterne J. Longitudinal trends in causes of death among adults with HIV on antiretroviral therapy in Europe and North America from 1996 to 2020: a collaboration of cohort studies. The Lancet HIV 2024, 11: e176-e185. PMID: 38280393, DOI: 10.1016/s2352-3018(23)00272-2.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCause-specific mortalityAvailability of effective antiretroviral therapyAll-cause mortalityRates of all-cause mortalityPatterns of cause-specific mortalityCause-specific mortality ratesCohort studyAdjusted mortality rate ratiosAntiretroviral Therapy Cohort CollaborationMortality rate ratiosInternational Classification of DiseasesMortality rateLongitudinal trendsAccident-related mortalityRates of cause-specific mortalityProportion of deathsClassification of DiseasesAIDS-related mortalityAIDS-related deathsAntiretroviral therapyInvestigate longitudinal trendsIncreased life expectancyInjection drug useHIV ageObservational cohort study
2007
Co-morbid medical and psychiatric illness and substance abuse in HCV-infected and uninfected veterans
Butt A, Khan U, McGinnis K, Skanderson M, Kent Kwoh C. Co-morbid medical and psychiatric illness and substance abuse in HCV-infected and uninfected veterans. Journal Of Viral Hepatitis 2007, 0: 070729180316002-???. DOI: 10.1111/j.1365-2893.2007.00885.x.Peer-Reviewed Original Research