Does Initiation of Basal Insulin Analogs in Patients with Type 2 Diabetes Mellitus Confer Advantages over Neutral Protamine Hagedorn (NPH) for Severe Hypoglycemia and Glycemic Control?
LIPSKA K, PARKER M, MOFFET H, HUANG E, KARTER A. Does Initiation of Basal Insulin Analogs in Patients with Type 2 Diabetes Mellitus Confer Advantages over Neutral Protamine Hagedorn (NPH) for Severe Hypoglycemia and Glycemic Control? Diabetes 2018, 67 DOI: 10.2337/db18-1311-p.Peer-Reviewed Original ResearchNeutral protamine HagedornType 2 diabetesReal-world clinical practiceSevere hypoglycemiaGlycemic controlInsulin analoguesClinical practiceKaiser Permanente Northern CaliforniaDiabetes medication useInsulin analogue useBasal insulin analoguesClinical trial populationsType of insulinHealth plan coverageHazard ratioInsulin initiationNPH insulinPatient characteristicsBasal insulinHemoglobin A1cMedication useSulfonylurea treatmentTrial populationHypoglycemic eventsNocturnal hypoglycemia