2005
Multiple melanocortin receptors are expressed in bone cells
Zhong Q, Sridhar S, Ruan L, Ding KH, Xie D, Insogna K, Kang B, Xu J, Bollag RJ, Isales CM. Multiple melanocortin receptors are expressed in bone cells. Bone 2005, 36: 820-831. PMID: 15804492, DOI: 10.1016/j.bone.2005.01.020.Peer-Reviewed Original ResearchMeSH KeywordsAdrenocorticotropic HormoneAnimalsBase SequenceBlotting, NorthernBlotting, SouthernCyclic AMPDNA PrimersHumansImmunohistochemistryMiceOligonucleotide Array Sequence AnalysisOsteoblastsPro-OpiomelanocortinProtein BindingRatsReceptors, CorticotropinReceptors, MelanocortinReverse Transcriptase Polymerase Chain ReactionRNA, MessengerThymidineConceptsMelanocortin receptorsBone turnoverOsteoclastic cellsReceptor familySteroid hormone secretionBone cellsMelanocortin receptor familyFamily of receptorsHormone secretionBeta-endorphinSpecific effectsPOMC fragmentsPOMC mRNACell subpopulationsAlpha betaGamma-MSHReceptorsPeptide hormonesPOMCG proteinsVivo dataBoneHormoneOsteoblastic cellsVariety of genes
1989
Synthetic Parathyroid Hormone-Like Protein-(1–74): Biochemical and Physiological Characterization*
STEWART A, ELLIOT J, BURTIS W, WU T, INSOGNA K. Synthetic Parathyroid Hormone-Like Protein-(1–74): Biochemical and Physiological Characterization*. Endocrinology 1989, 124: 642-648. PMID: 2912692, DOI: 10.1210/endo-124-2-642.Peer-Reviewed Original ResearchConceptsAmino acid compositionDirect amino acid sequencingAmino acid sequencingAcid compositionPhysiological characterizationN-terminusParathyroid hormone-like proteinRenal cortical adenylate cyclaseFetal rat long bonesInternal sequencesTransduction mechanismsCortical adenylate cyclasePhysiological comparisonPTH-like proteinHormone-like proteinProteolytic fragmentsRat long bonesAdenylate cyclase assayBovine PTHProteinPTH receptorFull-length peptidePeptide hormonesSynthetic peptidesNovel class