2003
Torus Palatinus: A New Anatomical Correlation with Bone Density in Postmenopausal Women
Belsky JL, Hamer JS, Hubert JE, Insogna K, Johns W. Torus Palatinus: A New Anatomical Correlation with Bone Density in Postmenopausal Women. The Journal Of Clinical Endocrinology & Metabolism 2003, 88: 2081-2086. PMID: 12727958, DOI: 10.1210/jc.2002-021726.Peer-Reviewed Original ResearchConceptsBone densityTorus palatinusPostmenopausal womenZ-scoreDual energy x-ray absortiometryNormal postmenopausal womenPostmenopausal female subjectsBody mass indexBone mineral densityBone density measurementsBone density assessmentHigher bone densityMass indexCaucasian womenMineral densityCommunity physiciansUnselected populationAnatomical correlationLumbar vertebraeFemale subjectsDensity assessmentPalatinusOral exostosesWomenPossible correlation
2002
High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5
Boyden LM, Mao J, Belsky J, Mitzner L, Farhi A, Mitnick MA, Wu D, Insogna K, Lifton RP. High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5. New England Journal Of Medicine 2002, 346: 1513-1521. PMID: 12015390, DOI: 10.1056/nejmoa013444.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersBone DensityCase-Control StudiesChromosomes, Human, Pair 11FemaleGenes, DominantGenotypeHumansIntercellular Signaling Peptides and ProteinsLDL-Receptor Related ProteinsLow Density Lipoprotein Receptor-Related Protein-5MaleMandibleMutation, MissenseOsteogenesisPalatePedigreePoint MutationProteinsProto-Oncogene ProteinsRadiographyReceptors, LDLSignal TransductionSyndromeWnt ProteinsZebrafish ProteinsConceptsLow-density lipoprotein receptor-related protein 5Higher bone densityProtein 5Bone densityDevelopmental proteinsLipoprotein receptor-related protein 5Fruit flyGenetic analysisDeep mandibleWnt activityTorus palatinusWnt pathwayFunction mutationsWntMajor public health problemNormal glycineBiochemical analysisMutationsTreatment of osteoporosisHigh bone massPublic health problemCodon 171Potential targetAutosomal dominant syndromeGenes
1997
Estrogen Replacement Therapy: New Options, Continuing Concerns-Reply
Insogna K, Concato J, Henrich J. Estrogen Replacement Therapy: New Options, Continuing Concerns-Reply. JAMA 1997, 277: 1516-1517. DOI: 10.1001/jama.1997.03540430028020.Peer-Reviewed Original ResearchBreast cancer riskBreast cancerBone densityCancer riskLow endogenous estrogen levelsHigh endogenous estrogenEstrogen replacement therapyEndogenous estrogen levelsTreatment of osteoporosisHigher bone densityAfrican American womenEstrogen levelsReplacement therapyExogenous estrogenEstrogen influenceEndogenous estrogensLower riskCancerWomenOsteoporosisRiskEstrogenNew optionsTherapyBMD