Boning Up on Estrogen: New Options, New Concerns
Insogna K, Concato J, Henrich J. Boning Up on Estrogen: New Options, New Concerns. JAMA 1996, 276: 1430-1432. DOI: 10.1001/jama.1996.03540170074037.Peer-Reviewed Original ResearchHormone replacement therapyPostmenopausal osteoporosisOral hormone replacement therapyRegular uterine bleedingInitiation of treatmentLong-term adherenceAlternative regimenEstrogen replacementPostmenopausal womenUterine bleedingProgestational agentsIntermittent administrationBone lossReplacement therapyOnly drugBone breakdownFracture ratesEstrogenWomenOsteoporosisDaily useNew optionsRecent studiesTreatmentBleeding