2021
Lessons Learned From COVID-19 Contact Tracing During a Public Health Emergency: A Prospective Implementation Study
Shelby T, Schenck C, Weeks B, Goodwin J, Hennein R, Zhou X, Spiegelman D, Grau LE, Niccolai L, Bond M, Davis JL. Lessons Learned From COVID-19 Contact Tracing During a Public Health Emergency: A Prospective Implementation Study. Frontiers In Public Health 2021, 9: 721952. PMID: 34490198, PMCID: PMC8417826, DOI: 10.3389/fpubh.2021.721952.Peer-Reviewed Original ResearchConceptsProspective implementation studyOutreach callsContact tracingAge-related disparitiesPublic health nursesRE-AIM implementation frameworkMultivariable regression modelsTimeliness of caseImplementation studyPublic health responsePublic health emergencyMedian timeHealth nursesAfrican American casesHealth responseInfectious diseasesFuture epidemicsDays of exposureHealth emergencyCOVID-19System-level predictorsRegression modelsCOVID-19 Contact TracingDaysPredictorsNew bullous lesions in a 72-year-old woman
Mendoza H, Goodwin J, Gehlhausen J, Odell I, McNiff J, Gnanapandithan K. New bullous lesions in a 72-year-old woman. Cleveland Clinic Journal Of Medicine 2021, 88: 319-324. PMID: 34078615, DOI: 10.3949/ccjm.88a.20180.Peer-Reviewed Case Reports and Technical Notes
2017
The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition
Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, Yoo H, Chen M, Ahn JM, Minna JD, Helke KL, Singh PK, Shackelford DB, Kim JW. The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition. Nature Communications 2017, 8: 15503. PMID: 28548087, PMCID: PMC5458561, DOI: 10.1038/ncomms15503.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma of LungAdultAgedAged, 80 and overAnimalsCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellCell Line, TumorCohort StudiesDeoxyglucoseFemaleFluorodeoxyglucose F18Gene Expression ProfilingGene Expression Regulation, NeoplasticGlucoseGlucose Transporter Type 1GlycolysisHumansHydroxybenzoatesLungLung NeoplasmsMaleMiceMice, NudeMiddle AgedPhenotypePositron-Emission TomographyPrognosisSurvival AnalysisUp-RegulationXenograft Model Antitumor AssaysConceptsNon-small cell lung cancerSquamous cell carcinomaLung SqCCCell carcinomaNSCLC subtypesGlycolytic inhibitionLung squamous cell carcinomaCell lung cancerPatient-derived xenograftsNSCLC tumor samplesNSCLC cell linesCancer Genome AtlasClinical presentationPoor prognosisTherapeutic optionsLung cancerPredominant subtypeDistinct metabolic phenotypesSelective vulnerabilityLung adenocarcinomaMurine modelTherapeutic strategiesSqCCTumor samplesMetabolic signatures