2020
Practice patterns and recommendations for pediatric image‐guided radiotherapy: A Children's Oncology Group report
Hua C, Vern‐Gross T, Hess CB, Olch AJ, Alaei P, Sathiaseelan V, Deng J, Ulin K, Laurie F, Gopalakrishnan M, Esiashvili N, Wolden SL, Krasin MJ, Merchant TE, Donaldson SS, FitzGerald TJ, Constine LS, Hodgson DC, Haas‐Kogan D, Mahajan A, Laack NN, Marcus KJ, Taylor PA, Ahern VA, Followill DS, Buchsbaum JC, Breneman JC, Kalapurakal JA. Practice patterns and recommendations for pediatric image‐guided radiotherapy: A Children's Oncology Group report. Pediatric Blood & Cancer 2020, 67: e28629. PMID: 32776500, PMCID: PMC7774502, DOI: 10.1002/pbc.28629.Peer-Reviewed Original ResearchConceptsChildren's Oncology GroupImage-guided radiotherapyOncology GroupPractice patternsOncology disciplinesChildren's Oncology Group reportPaediatric radiotherapy patientsTreatment modalitiesExpert guidelinesDose reductionRadiotherapy patientsPractice recommendationsSetup correctionAdaptive therapyRadiotherapyImage guidanceReportMember surveyGroup ReportPatientsTherapyCliniciansA general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation
Liang Y, Muhammad W, Hart GR, Nartowt BJ, Chen ZJ, Yu JB, Roberts KB, Duncan JS, Deng J. A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation. Scientific Reports 2020, 10: 9808. PMID: 32555530, PMCID: PMC7300009, DOI: 10.1038/s41598-020-66844-7.Peer-Reviewed Original ResearchConceptsPhoton transportBoundary crossing algorithmMonte Carlo particle transport codeMonte Carlo methodTransport simulationsAcceptance-rejection samplingRadiotherapy dose calculationsPhoto-electric effectParticle transport codeEGSnrc simulationsCarlo methodBremsstrahlung eventsInelastic scatteringPair productionRayleigh scatteringThread divergenceMC simulationsTransport codeMC codeHistory schemeParticle transportCrossing algorithmInverseElectron transportSimulation accuracy
2019
Beam modeling and beam model commissioning for Monte Carlo dose calculation‐based radiation therapy treatment planning: Report of AAPM Task Group 157
Charlie C, Chetty IJ, Deng J, Faddegon B, Jiang SB, Li J, Seuntjens J, Siebers JV, Traneus E. Beam modeling and beam model commissioning for Monte Carlo dose calculation‐based radiation therapy treatment planning: Report of AAPM Task Group 157. Medical Physics 2019, 47: e1-e18. PMID: 31679157, DOI: 10.1002/mp.13898.Peer-Reviewed Original ResearchMeSH KeywordsModels, TheoreticalMonte Carlo MethodRadiation DosageRadiotherapy DosageRadiotherapy Planning, Computer-AssistedResearch ReportConceptsBeam modelElectron beam dose calculationsMonte Carlo methodRadiotherapy dose calculationsTreatment planning systemDose calculationsClinical beam modelCarlo methodBeam modelingRadiation therapy treatment planningMC simulationsTherapy treatment planningElectron beamTreatment headClinical photonRadiotherapy treatment planningGeneral approachCalculationsHigh accuracyPractical procedureAccuracyModelClinical physicistsAnalytical methodBeam delivery
2018
Imaging Dose, Cancer Risk and Cost Analysis in Image-guided Radiotherapy of Cancers
Zhou L, Bai S, Zhang Y, Ming X, Zhang Y, Deng J. Imaging Dose, Cancer Risk and Cost Analysis in Image-guided Radiotherapy of Cancers. Scientific Reports 2018, 8: 10076. PMID: 29973695, PMCID: PMC6031630, DOI: 10.1038/s41598-018-28431-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBone Marrow CellsBrainChildChild, PreschoolCone-Beam Computed TomographyCost-Benefit AnalysisFemaleHumansInfantLungMaleMiddle AgedMonte Carlo MethodNeoplasmsPhantoms, ImagingRadiation DosageRadiotherapy DosageRadiotherapy, Image-GuidedRisk FactorsThoraxYoung AdultConceptsCancer riskAssociated cancer riskImage-guided radiotherapyImaging proceduresLifetime attributable riskImaging dosesAverage lifetime attributable riskRadiological imaging proceduresRed bone marrowRetrospective studyCancer patientsLung cancerAttributable riskCancer incidenceBilling codesIndividual patientsBone marrowBrain cancerImage guidance proceduresPelvic scanPatientsCancerOrgan dosesRadiotherapyDoses
2016
Radiation-induced heart disease in lung cancer radiotherapy
Ming X, Feng Y, Yang C, Wang W, Wang P, Deng J. Radiation-induced heart disease in lung cancer radiotherapy. Medicine 2016, 95: e5051. PMID: 27741117, PMCID: PMC5072944, DOI: 10.1097/md.0000000000005051.Peer-Reviewed Original ResearchMeSH KeywordsGlobal HealthHumansIncidenceLung NeoplasmsRadiation InjuriesRadiotherapy DosageRisk FactorsConceptsRadiation-induced heart diseaseLung cancer radiotherapyLung cancer patientsPotential risk factorsCancer radiotherapyCancer patientsCardiac toxicityHeart diseaseRisk factorsRadiation treatmentLung cancer survivorsLate side effectsHistory of heartTypes of cancerCardiac complicationsCrude incidencePulmonary diseaseBetter prognosisLobar locationBenign diseaseCancer survivorsLung cancerTreatment modalitiesPatient prognosisBreast cancerEnergy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study
Zhang Y, Feng Y, Ming X, Deng J. Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study. BioMed Research International 2016, 2016: 7319843. PMID: 26977413, PMCID: PMC4763028, DOI: 10.1155/2016/7319843.Peer-Reviewed Original ResearchConceptsIMRT plansPediatric brain tumorsNovel treatment modalitiesNormal tissue sparingDifferent tumor sitesDosimetric gainLung cancerTreatment modalitiesIndividual patientsBrain tumorsTissue sparingIMRT techniqueTumor sitePersonalized carePhoton radiotherapyThyroid lesionsDose distributionIntegral doseRadiotherapy treatmentInverse planning systemPatientsRadiotherapyFeasibility studyModern radiotherapy treatmentsClinical IMRT plans
2015
Cardiac Exposure in the Dynamic Conformal Arc Therapy, Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy of Lung Cancer
Ming X, Feng Y, Liu H, Zhang Y, Zhou L, Deng J. Cardiac Exposure in the Dynamic Conformal Arc Therapy, Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy of Lung Cancer. PLOS ONE 2015, 10: e0144211. PMID: 26630566, PMCID: PMC4667972, DOI: 10.1371/journal.pone.0144211.Peer-Reviewed Original ResearchConceptsDynamic conformal arc therapyLung cancer patientsIntensity-modulated radiotherapyIrradiated heart volumeCardiac exposureHeart distanceConformal arc therapyCancer patientsHeart volumeArc therapyHeart doseCardiac diseaseLong-term cardiac toxicityMean heart doseMean heart dosesRight lung tumorLung cancer treatmentVolumetric Modulated Arc TherapyRadiotherapy treatment modalitiesInstitutional review boardLung cancer radiotherapyHeart dosesHeart sparingCardiac complicationsHodgkin's disease
2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplants
2006
Limitations of silicon diodes for clinical electron dosimetry
Song H, Ahmad M, Deng J, Chen Z, Yue NJ, Nath R. Limitations of silicon diodes for clinical electron dosimetry. Radiation Protection Dosimetry 2006, 120: 56-59. PMID: 16772305, DOI: 10.1093/rpd/ncj007.Peer-Reviewed Original ResearchPotential impact of prostate edema on the dosimetry of permanent seed implants using the new (model CS‐1) seeds
Chen Z, Deng J, Roberts K, Nath R. Potential impact of prostate edema on the dosimetry of permanent seed implants using the new (model CS‐1) seeds. Medical Physics 2006, 33: 968-975. PMID: 16696473, DOI: 10.1118/1.2179170.Peer-Reviewed Original Research
2004
Modelling 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning
Deng J, Guerrero T, Ma C, Nath R. Modelling 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning. Physics In Medicine And Biology 2004, 49: 1689-1704. PMID: 15152924, DOI: 10.1088/0031-9155/49/9/007.Peer-Reviewed Original ResearchMeSH KeywordsModels, TheoreticalMonte Carlo MethodParticle AcceleratorsPhantoms, ImagingPhotonsRadiosurgeryRadiotherapy DosageConceptsMV photon beamMonte Carlo treatmentPhoton beamsPhase spaceEGS4/BEAM systemPercent depth dose curvesParticle phase spaceMonte Carlo treatment planningDepth dose curvesFull phase spaceDose calculationsStereotactic radiosurgery systemContaminant electronsCircular planar sourceMonte Carlo systemPrimary photonsMultiple source modelDose profilesSecondary collimatorDose curvesTotal maximum doseDose contributionBeamBeam systemOriginal phase space
2003
Commissioning 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning
Deng J, Ma C, Hai J, Nath R. Commissioning 6 MV photon beams of a stereotactic radiosurgery system for Monte Carlo treatment planning. Medical Physics 2003, 30: 3124-3134. PMID: 14713079, DOI: 10.1118/1.1624753.Peer-Reviewed Original ResearchConceptsMonte Carlo dose calculationsMonte Carlo treatment planningBeam phase spaceOutput factorsCentral axis depth dose curvesDose profilesMonte Carlo treatmentMeasurement dataMultiple source modelCyberknife stereotactic radiosurgery systemPhase spaceMV photon beamDepth dose curvesDose calculationsSource modelStereotactic radiosurgery systemFluence distributionStandard measurement dataSource distributionPhoton beamsAxis distanceEnergy spectrumCollimator sizeDose curvesAveraging effectDose correlation for thoracic motion in radiation therapy of breast cancer
Ding M, Li J, Deng J, Fourkal E, Ma C. Dose correlation for thoracic motion in radiation therapy of breast cancer. Medical Physics 2003, 30: 2520-2529. PMID: 14528974, DOI: 10.1118/1.1603744.Peer-Reviewed Original ResearchMeSH KeywordsArtifactsBreast NeoplasmsHumansMammographyMotionMovementOnline SystemsPhantoms, ImagingRadiographic Image Interpretation, Computer-AssistedRadiography, ThoracicRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRadiotherapy, Computer-AssistedReproducibility of ResultsRespirationSensitivity and SpecificityStatistics as TopicThoraxTomography, X-Ray ComputedConceptsBreathing patternDose correlationBreast cancerChest wall motionChest wall movementPatient's breathing patternDose dataRadiation therapyThoracic motionRadiotherapy treatmentTreatment planningExpiration phaseDifferent breathing phasesFinal dose distributionCancerBreathing phasesPatient anatomyWall motionTreatmentDose distributionCT dataBreathing levelTherapyDosePatient geometryA comparative dosimetric study on tangential photon beams, intensity-modulated radiation therapy (IMRT) and modulated electron radiotherapy (MERT) for breast cancer treatment
Ma C, Ding M, Li JS, Lee MC, Pawlicki T, Deng J. A comparative dosimetric study on tangential photon beams, intensity-modulated radiation therapy (IMRT) and modulated electron radiotherapy (MERT) for breast cancer treatment. Physics In Medicine And Biology 2003, 48: 909-924. PMID: 12701895, DOI: 10.1088/0031-9155/48/7/308.Peer-Reviewed Original ResearchConceptsIntensity-modulated radiation therapyTangential photon beamsContralateral breastBreast cancerRadiation therapyTreatment planMaximum doseBreast cancer treatmentTreatment optimizationComparative dosimetric studyBreast treatment plansPhoton treatment plansPhoton beamsElectron radiotherapySuperficial targetsMultiple beam anglesLungMedium dosesDose conformityTangential beamsNormal tissuesCancer treatmentMERT plansIMRT plansMV photon beamA quality assurance phantom for IMRT dose verification
Ma C, Jiang SB, Pawlicki T, Chen Y, Li JS, Deng J, Boyer AL. A quality assurance phantom for IMRT dose verification. Physics In Medicine And Biology 2003, 48: 561-572. PMID: 12696795, DOI: 10.1088/0031-9155/48/5/301.Peer-Reviewed Original Research
2002
A Monte Carlo investigation of fluence profiles collimated by an electron specific MLC during beam delivery for modulated electron radiation therapy
Deng J, Lee MC, Ma C. A Monte Carlo investigation of fluence profiles collimated by an electron specific MLC during beam delivery for modulated electron radiation therapy. Medical Physics 2002, 29: 2472-2483. PMID: 12462711, DOI: 10.1118/1.1513160.Peer-Reviewed Original ResearchConceptsFluence profilesVarian Clinac 2100C linear acceleratorElectron radiation therapyElectron beamMonte Carlo methodBeam energyBeam deliveryMonte Carlo investigationElectron beam energyCarlo methodMonte CarloOff-axis locationBEAM codeSigmoid functionLeaf endsEnergy dependenceInverse planning algorithmLinear acceleratorVariable energyMLC aperturesOperatorsBeamField sizeDose distributionMultileaf collimator
2001
Monte Carlo based treatment planning for modulated electron beam radiation therapy
Lee M, Deng J, Li J, Jiang S, Ma C. Monte Carlo based treatment planning for modulated electron beam radiation therapy. Physics In Medicine And Biology 2001, 46: 2177-2199. PMID: 11512618, DOI: 10.1088/0031-9155/46/8/310.Peer-Reviewed Original ResearchConceptsElectron multileaf collimatorIntensity mapsDose distributionElectron radiation therapyElectron beamletsElectron energyElectron beam radiation therapyAir scatteringMonte CarloBremsstrahlung contributionConformal dose distributionsMonte Carlo simulationsBeamletsScatter dosesTreatment planning systemElectronsMultileaf collimatorCarlo simulationsBreast plansIrregular targetsLeaf transportCarloScatteringMonte Carlo generationCollimator
2000
Monte Carlo verification of IMRT dose distributions from a commercial treatment planning optimization system
Ma C, Pawlicki T, Jiang SB, Li JS, Deng J, Mok E, Kapur A, Xing L, Ma L, Boyer AL. Monte Carlo verification of IMRT dose distributions from a commercial treatment planning optimization system. Physics In Medicine And Biology 2000, 45: 2483-2495. PMID: 11008950, DOI: 10.1088/0031-9155/45/9/303.Peer-Reviewed Original ResearchConceptsMonte Carlo simulationsFinite-size pencil beam (FSPB) algorithmCorvus systemCarlo simulationsOptimization systemIMRT dose distributionsRadiotherapy dose calculationsMonte Carlo treatment planning systemPencil beam algorithmDose distributionMonte CarloBeam algorithmHeterogeneous phantomsMonte Carlo verificationHomogeneous phantomBeam energyCylindrical water phantomIMRT fieldsDose calculationsWater phantomTreatment planning systemField sizeTarget shapeAlgorithmSimulations