2024
Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction.
Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.Peer-Reviewed Original ResearchConceptsMarital/partner statusPsychosocial factorsAcute myocardial infarctionYoung adultsHospital dischargeYear of hospital dischargeYoung acute myocardial infarctionAssociated with 1.3-foldCohort of young adultsLong-term readmissionCox proportional hazards modelsStatus interactionSimilar-aged menMyocardial infarctionProportional hazards modelUnpartnered statusPatient interviewsPhysician panelCardiovascular healthHospital readmissionSocioeconomic factorsAMI survivorsSequential adjustmentCardiac readmissionMultiple imputation
2023
Changes in Older Adult Trauma Quality When Evaluated Using Longer-Term Outcomes vs In-Hospital Mortality
Zogg C, Cooper Z, Peduzzi P, Falvey J, Castillo-Angeles M, Kodadek L, Staudenmayer K, Davis K, Tinetti M, Lichtman J. Changes in Older Adult Trauma Quality When Evaluated Using Longer-Term Outcomes vs In-Hospital Mortality. JAMA Surgery 2023, 158: e234856. PMID: 37792354, PMCID: PMC10551815, DOI: 10.1001/jamasurg.2023.4856.Peer-Reviewed Original ResearchConceptsHospital-level factorsTraumatic brain injurySevere traumatic brain injuryHospital mortalityTrauma QualityOlder adultsHip fractureComposite scoreHigher risk-adjusted oddsLevel 1 trauma centerIn-Hospital MortalityRisk-adjusted oddsLong-term outcomesMultivariable logistic regressionNontrauma centersTrauma patientsTerm outcomesTrauma centerPrimary diagnosisBrain injuryTrauma systemMAIN OUTCOMEMedicare feeService claimsForms of traumaOutcomes after ischemic stroke for dual-eligible Medicare-Medicaid beneficiaries in the United States
Leifheit E, Wang Y, Goldstein L, Lichtman J. Outcomes after ischemic stroke for dual-eligible Medicare-Medicaid beneficiaries in the United States. PLOS ONE 2023, 18: e0292546. PMID: 37797070, PMCID: PMC10553827, DOI: 10.1371/journal.pone.0292546.Peer-Reviewed Original ResearchConceptsStroke hospitalization ratesMedicare beneficiariesIschemic strokeHospitalization ratesUS acute care hospitalsDual-eligible patientsLong-term mortalityUS Medicare beneficiariesIschemic stroke hospitalizationsPost-stroke outcomesAcute care hospitalsService Medicare beneficiariesDual-eligible statusDual-eligible beneficiariesPercentage of beneficiariesCause readmissionHigher readmissionClinical factorsDual eligibilityAdjusted analysisPoor outcomeStroke patientsCox regressionStroke hospitalizationsPrincipal diagnosisSex‐Specific Associations of Obstructive Sleep Apnea Risk With Patient Characteristics and Functional Outcomes After Acute Myocardial Infarction: Evidence From the VIRGO Study
Gupta A, Barthel A, Mahajan S, Dreyer R, Yaggi H, Bueno H, Lichtman J, Krumholz H. Sex‐Specific Associations of Obstructive Sleep Apnea Risk With Patient Characteristics and Functional Outcomes After Acute Myocardial Infarction: Evidence From the VIRGO Study. Journal Of The American Heart Association 2023, 12: e027225. PMID: 37702090, PMCID: PMC10547292, DOI: 10.1161/jaha.122.027225.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaAcute myocardial infarctionHigh OSA riskOSA riskSex-specific associationsFunctional outcomeHealth statusHigh riskVIRGO StudyMyocardial infarctionDepressive symptomsHistory of OSATime of AMIImpact of OSAObstructive sleep apnea riskLow-risk patientsSleep apnea riskMajority of patientsTime of presentationSex-specific outcomesWorse health statusHigh-risk menPoor health statusMental health statusPoor health outcomesImpact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction
Zhu C, Dreyer R, Li F, Spatz E, Caraballo‐Cordovez C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2023, 12: e030031. PMID: 37589125, PMCID: PMC10547344, DOI: 10.1161/jaha.123.030031.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac-specific qualityGeneric health statusMyocardial infarctionBaseline healthMarital stressHealth outcomesHealth statusWorse patient-reported outcomesMental healthYoung adultsObservational cohort studyPatient-reported outcomesSocioeconomic factorsWorse mental healthReadmission 1Cause readmissionCohort studyYounger patientsRoutine screeningDepressive symptomsGreater oddsAnginaMale participantsOutcomesAssociation of short-term hospital-level outcome metrics with 1-year mortality and recurrence for US Medicare beneficiaries with ischemic stroke
Wang Y, Leifheit E, Goldstein L, Lichtman J. Association of short-term hospital-level outcome metrics with 1-year mortality and recurrence for US Medicare beneficiaries with ischemic stroke. PLOS ONE 2023, 18: e0289790. PMID: 37561680, PMCID: PMC10414659, DOI: 10.1371/journal.pone.0289790.Peer-Reviewed Original ResearchConceptsIschemic strokeInverse probability weightsStroke patientsCause mortalityOutcome metricsLower riskUS hospitalsBetter long-term outcomesRecurrent stroke rateIschemic stroke recurrenceIschemic stroke patientsLong-term outcomesUS Medicare beneficiariesPerformance categoriesIntermediate hospitalsRecurrent strokeStroke recurrenceCohort studyClinical factorsRecurrence ratePrincipal diagnosisPatient riskStroke rateReadmission measuresCox modelSystematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds
Li Z, Wang Z, Chen Z, Voegeli H, Lichtman J, Smith P, Liu J, DeWan A, Hoh J. Systematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds. BMC Genomics 2023, 24: 302. PMID: 37277710, PMCID: PMC10240460, DOI: 10.1186/s12864-023-09390-6.Peer-Reviewed Original ResearchConceptsBreed-specific traitsGenetic signaturesShort tandem repeatsSingle nucleotide polymorphismsSNP clustersGenome-wide association studiesDog breedsNovel single nucleotide polymorphismsWhole-genome sequencing technologyFrame-shifting indelsNovel genetic signaturesNonsense variantGenomic structureUnknown phenotypeSTR expansionsGenomic regionsPhenotypic traitsSequencing technologiesGenetic insightsAssociation studiesTandem repeatsDisease predispositionSequence mapsNucleotide polymorphismsTraitsSex Difference in Outcomes of Acute Myocardial Infarction in Young Patients
Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNoncardiac hospitalizationsSubdistribution HRYounger patientsMyocardial infarctionSex differencesYoung womenCause-specific hospitalizationsCause of hospitalizationWorse health statusSignificant sex disparityNoncardiovascular hospitalizationsVIRGO StudyIndex episodeAdverse outcomesIncidence rateHospitalizationHigh riskSex disparitiesHealth statusPatientsU.S. hospitalsWomenInfarctionOutcomesHigher burden of cardiometabolic and socioeconomic risk factors in women with type 2 diabetes: an analysis of the Glycemic Reduction Approaches in Diabetes (GRADE) baseline cohort
Gulanski B, Butera N, Krause-Steinrauf H, Lichtman J, Harindhanavudhi T, Green J, Suratt C, AbouAssi H, Desouza C, Ahmann A, Wexler D, Aroda V, Crandall J, McKee, Behringer-Massera S, Brown-Friday J, Xhori E, Ballentine-Cargill K, Duran S, Estrella H, de la torre S, Lukin J, Phillips L, Burgess E, Olson D, Rhee M, Wilson P, Raines T, Boers J, Costello J, Maher-Albertelli M, Mungara R, Savoye L, White C, Gullett C, Holloway L, Morehead F, Person S, Sibymon M, Tanukonda S, Adams C, Ross A, Balasubramanyam A, Gaba R, Hattery E, Ideozu A, Jimenez J, Montes G, Wright C, Hollander P, Roe E, Jackson A, Smiley A, Burt P, Estrada L, Chionh K, Ismail-Beigi F, Falck-Ytter C, Kassem L, Sood A, Tiktin M, Kulow T, Newman C, Stancil K, Cramer B, Iacoboni J, Kononets M, Sanders C, Tucker L, Werner A, Maxwell A, McPhee G, Patel C, Colosimo L, Krol A, Goland R, Pring J, Alfano L, Kringas P, Hausheer C, Tejada J, Gumpel K, Kirpitch A, Schneier H, Green J, AbouAssi H, Chatterjee R, Feinglos M, Jones J, Khan J, Zimmer R, Furst M, Satterwhite B, Thacker C, Kreider K, Mariash C, Mather K, Ismail H, Lteif A, Mullen M, Hamilton T, Patel N, Riera G, Jackson M, Pirics V, Aguillar D, Howard D, Hurt S, Bergenstal R, Carlson A, Martens T, Johnson M, Hill R, Hyatt J, Jensen C, Madden M, Martin D, Willis H, Konerza W, Yang S, Kleeberger K, Passi R, Fortmann S, Herson M, Mularski K, Glauber H, Prihoda J, Ash B, Carlson C, Ramey P, Schield E, Torgrimson-Ojerio B, Arnold K, Kauffman B, Panos E, Sahnow S, Bays K, Berame K, Cook J, Ghioni D, Gluth J, Schell K, Criscola J, Friason C, Jones S, Nazarov S, Barzilay J, Rassouli N, Puttnam R, Ojoawo B, Nelson R, Curtis M, Hollis B, Sanders-Jones C, Stokes K, El-Haqq Z, Kolli A, Tran T, Wexler D, Larkin M, Meigs J, Chambers B, Dushkin A, Rocchio G, Yepes M, Steiner B, Dulin H, Cayford M, Chu K, DeManbey A, Hillard M, Martin K, Thangthaeng N, Gurry L, Kochis R, Raymond E, Ripley V, Stevens C, Park J, Aroda V, Ghazi A, Magee M, Ressing A, Loveland A, Hamm M, Hurtado M, Kuhn A, Leger J, Manandhar L, Mwicigi F, Sanchez O, Young T, Garg R, Lagari-Libhaber V, Florez H, Valencia, Marks J, Casula S, Oropesa-Gonzalez L, Hue L, Cuadot A, Nieto-Martinez R, Veliz A, Gutt M, Kendal Y, Veciana B, Ahmann A, Aby-Daniel D, Joarder F, Morimoto V, Sprague C, Yamashita D, Cady N, Rivera-Eschright N, Kirchhoff P, Gomez B, Adducci J, Goncharova A, Hox S, Petrovitch H, Matwichyna M, Jenkins V, Broadwater L, Ishii R, Bermudez N, Hsia D, Cefalu W, Greenway F, Waguespack C, King E, Fry G, Dragg A, Gildersleeve B, Arceneaux J, Haynes N, Thomassie A, Pavlionis M, Bourgeois B, Hazlett C, Mudaliar S, Henry R, Boeder S, Pettus J, Diaz E, Garcia-Acosta D, Maggs S, DeLue C, Stallings A, Castro E, Hernandez S, Krakoff J, Curtis J, Killean T, Khalid M, Joshevama E, Diaz E, Martin D, Tsingine K, Karshner T, Albu J, Pi-Sunyer F, Frances S, Maggio C, Ellis E, Bastawrose J, Gong X, Banerji M, August P, Lee M, Lorber D, Brown N, Josephson D, Thomas L, Tsovian M, Cherian A, Jacobson M, Mishko M, Kirkman, Buse J, Dostou J, Machineni S, Young L, Bergamo K, Goley A, Kerr J, Largay J, Guarda S, Cuffee J, Culmer D, Fraser R, Almeida H, Coffer S, Debnam E, Kiker L, Morton S, Josey K, Fuller G, Garvey W, Cherrington A, Dyer D, Lawson M, Griffith O, Agne A, McCullars S, Cohen R, Craig J, Rogge M, Burton K, Kersey K, Wilson C, Lipp S, Meulen M, Adkins C, Onadeko T, Rasouli N, Baker C, Schroeder E, Razzaghi M, Lyon C, Penaloza R, Underkofler C, Lorch R, Douglass S, Steiner S, Sivitz W, Cline E, Knosp L, McConnell J, Lowe T, Herman W, Pop-Busui R, Tan M, Martin C, Waltje A, Katona A, Goodhall L, Eggleston R, Kuo S, Bojescu S, Bule S, Kessler N, LaSalle E, Whitley K, Seaquist E, Bantle A, Harindhanavudhi T, Kumar A, Redmon B, Bantle J, Coe M, Mech M, Taddese A, Lesne L, Smith S, Desouza C, Kuechenmeister L, Shivaswamy V, Burbach S, Rodriguez, Seipel K, Alfred A, Morales A, Eggert J, Lord G, Taylor W, Tillson R, Schade D, Adolphe A, Burge M, Duran-Valdez E, Martinez J, Bancroft A, Kunkel S, Ahmad F, McGinnis D, Pucchetti B, Scripsick E, Zamorano A, DeFronzo R, Cersosimo E, Abdul-Ghani M, Triplitt C, Juarez D, Garza R, Verastiqui H, Wright K, Puckett C, Raskin P, Rhee C, Abraham S, Jordan L, Sao S, Morton L, Smith O, Walker L, Schnurr-Breen L, Ayala R, Kreymer R, Sturgess D, Utzschneider K, Kahn, Wright L, Boyko E, Tsai E, Trence D, Trikudanathan S, Fattaleh B, Montgomery B, Atkinson K, Kozedub A, Concepcion T, Moak C, Prikhodko N, Rhothisen S, Elasy T, Martin S, Shackelford L, Goidel R, Hinkle N, Lovell C, Myers J, Hogan J, McGill J, Salam M, Schweiger T, Kissel S, Recklein C, Clifton M, Tamborlane W, Camp A, Gulanski B, Inzucchi, Pham K, Alguard M, Gatcomb P, Lessard K, Perez M, Iannone L, Montosa A, Magenheimer E, Cefalu W, Fradkin J, Burch H, Bremer A, Nathan D, Lachin J, Krause-Steinrauf H, Younes N, Bebu I, Butera N, Buys C, Fagan A, Gao Y, Ghosh A, Gramzinski, Hall S, Kazemi E, Legowski E, Liu H, Suratt C, Tripputi M, Arey A, Backman M, Bethepu J, Lund C, Dhaliwal P, McGee P, Mesimer E, Ngo L, Steffes M, Seegmiller J, Saenger A, Arends V, Gabrielson D, Conner T, Warren S, Day J, Huminik J, Scrymgeour A, Soliman E, Pokharel Y, Zhang Z, Campbell C, Hu J, Keasler L, Hensley S, Li Y, Mihalcea R, Min D, Perez-Rosas V, Prosser L, Resnicow K, Ye W, Shao H, Zhang P, Luchsinger J, Sanchez D, Assuras S, Groessl E, Sakha F, Chong H, Hillery N, Everett B, Abdouch I, Bahtiyar G, Brantley P, Broyles F, Canaris G, Copeland P, Craine J, Fein W, Gliwa A, Hope L, Lee, Meiners R, Meiners V, O’Neal H, Park J, Sacerdote A, Sledge E, Soni L, Steppel-Reznik J, Turchin A, Brooks-Worrell B, Hampe C, Palmer J, Shojaie A, Higgins J, Fischer L, Golden S, Gonzalez J, Naik A, Walker E, Lotenberg L, Gallivan J, Lim J, Tuncer D. Higher burden of cardiometabolic and socioeconomic risk factors in women with type 2 diabetes: an analysis of the Glycemic Reduction Approaches in Diabetes (GRADE) baseline cohort. BMJ Open Diabetes Research & Care 2023, 11: e003159. PMID: 37094945, PMCID: PMC10151943, DOI: 10.1136/bmjdrc-2022-003159.Peer-Reviewed Original ResearchConceptsBody mass indexRisk factorsSocioeconomic risk factorsCardiovascular diseaseGreater prevalenceContemporary cohortHigher mean body mass indexMean body mass indexType 2 diabetes mellitusBurden of CVDYoung womenBlood pressure targetsGlycemia Reduction ApproachesAngiotensin receptor blockersCardiometabolic risk factorsLow HDL cholesterolPowerful risk factorComparative effectiveness studiesGreater relative riskCross-sectional analysisMetformin monotherapyTarget LDLReceptor blockersPressure targetsSevere obesityAssociations Between Long-Term Air Pollutant Exposure and 30-Day All-Cause Hospital Readmissions in US Patients With Stroke
Tran P, Warren J, Leifheit E, Goldstein L, Lichtman J. Associations Between Long-Term Air Pollutant Exposure and 30-Day All-Cause Hospital Readmissions in US Patients With Stroke. Stroke 2023, 54: e126-e129. PMID: 36729388, PMCID: PMC11059199, DOI: 10.1161/strokeaha.122.042265.Peer-Reviewed Original ResearchConceptsLong-term air pollutant exposureAir pollutant exposureCause hospital readmissionHospital readmissionPollutant exposureMedicare beneficiaries agePerformance categoriesMatter 2.5Sulfur dioxide exposureCause readmission measureIschemic strokeStroke incidenceUS patientsHospital characteristicsSD increaseReadmissionCox modelReadmission measuresBeneficiaries ageLong-term exposureStrokePatientsMedicaid ServicesParticulate matter 2.5US feeAssociation of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction
Okafor C, Zhu C, Raparelli V, Murphy T, Arakaki A, D’Onofrio G, Tsang S, Smith M, Lichtman J, Spertus J, Pilote L, Dreyer R. Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction. JAMA Network Open 2023, 6: e2255843. PMID: 36787140, PMCID: PMC9929697, DOI: 10.1001/jamanetworkopen.2022.55843.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung adultsHospital readmissionBlack raceMyocardial infarctionRacial differencesCardiac factorsSociodemographic characteristicsBlack individualsOdds of readmissionObservational cohort studyMedical record abstractionRisk of readmissionWhite individualsAdults Aged 18Year of dischargePostdischarge readmissionVIRGO StudyCause readmissionCohort studyPrimary outcomeRecord abstractionMulticenter studyAged 18Male ratio
2022
The association of marital/partner status with patient-reported health outcomes following acute myocardial infarction or stroke: Protocol for a systematic review and meta-analysis
Zhu C, Tran P, Leifheit E, Spatz E, Dreyer R, Nyhan K, Wang S, Goldstein L, Lichtman J. The association of marital/partner status with patient-reported health outcomes following acute myocardial infarction or stroke: Protocol for a systematic review and meta-analysis. PLOS ONE 2022, 17: e0267771. PMID: 36378664, PMCID: PMC9665376, DOI: 10.1371/journal.pone.0267771.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresAcute myocardial infarctionMarital/partner statusPartner statusMyocardial infarctionHealth outcomesPatient-reported health outcomesPROSPERO registration numberRisk of biasPatient-centered factorsPeer-reviewed journalsPrimary outcomeSubgroup analysisThird reviewerOutcome measuresRegistration numberLower mortalitySystematic reviewEthics approvalStrokePartner supportMale participantsInfarctionFull textOutcomes
2015
2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Cardiovascular Endpoints Data Standards)
Hicks K, Tcheng J, Bozkurt B, Chaitman B, Cutlip D, Farb A, Fonarow G, Jacobs J, Jaff M, Lichtman J, Limacher M, Mahaffey K, Mehran R, Nissen S, Smith E, Targum S. 2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Cardiovascular Endpoints Data Standards). Journal Of Nuclear Cardiology 2015, 22: 1041-1144. PMID: 26204990, DOI: 10.1007/s12350-015-0209-1.Peer-Reviewed Original ResearchMeSH KeywordsAmerican Heart AssociationCardiologyCardiovascular DiseasesClinical Trials as TopicCommon Data ElementsConfidentialityDatabases, FactualEndpoint DeterminationHealth Insurance Portability and Accountability ActHumansQuality Assurance, Health CareQuality of Health CareReproducibility of ResultsResearch DesignSocieties, MedicalTerminology as TopicTranslational Research, BiomedicalTreatment OutcomeUnited States
2013
Seasonal Variation in 30-Day Mortality After Stroke
Lichtman JH, Jones SB, Wang Y, Leifheit-Limson EC, Goldstein LB. Seasonal Variation in 30-Day Mortality After Stroke. Stroke 2013, 44: 531-533. PMID: 23299494, PMCID: PMC3555561, DOI: 10.1161/strokeaha.112.670547.Peer-Reviewed Original Research
2012
30-Day Risk-Standardized Mortality and Readmission Rates After Ischemic Stroke in Critical Access Hospitals
Lichtman JH, Leifheit-Limson EC, Jones SB, Wang Y, Goldstein LB. 30-Day Risk-Standardized Mortality and Readmission Rates After Ischemic Stroke in Critical Access Hospitals. Stroke 2012, 43: 2741-2747. PMID: 22935397, PMCID: PMC3547601, DOI: 10.1161/strokeaha.112.665646.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesRisk-standardized readmission ratesAnnual hospital volumeIschemic strokeReadmission ratesHospital volumeVolume quartileHighest risk-standardized mortality ratesPoor short-term outcomeMedicare beneficiaries 65 yearsService Medicare beneficiaries 65 yearsHighest volume quartileHospital volume quartilesPrimary discharge diagnosisLow-volume hospitalsShort-term outcomesBeneficiaries 65 years
2011
30-Day Mortality and Readmission After Hemorrhagic Stroke Among Medicare Beneficiaries in Joint Commission Primary Stroke Center-Certified and Noncertified Hospitals
Lichtman JH, Jones SB, Leifheit-Limson EC, Wang Y, Goldstein LB. 30-Day Mortality and Readmission After Hemorrhagic Stroke Among Medicare Beneficiaries in Joint Commission Primary Stroke Center-Certified and Noncertified Hospitals. Stroke 2011, 42: 3387-3391. PMID: 22033986, PMCID: PMC3292255, DOI: 10.1161/strokeaha.111.622613.Peer-Reviewed Original ResearchConceptsSubarachnoid hemorrhageIntracerebral hemorrhageReadmission ratesHemorrhagic strokeMedicare beneficiariesJoint Commission Primary Stroke CentersLower risk-adjusted mortality ratesCox proportional hazards regressionRisk-adjusted readmission ratesRisk-adjusted mortality ratesIschemic stroke patientsPrimary discharge diagnosisPrimary stroke centerProportional hazards regressionService Medicare beneficiariesEffects of careHospital mortalityStroke centersStroke patientsDischarge diagnosisHazards regressionMortality rateBetter outcomesHospitalPatientsOutcomes after ischemic stroke for hospitals with and without Joint Commission–certified primary stroke centers
Lichtman JH, Jones SB, Wang Y, Watanabe E, Leifheit-Limson E, Goldstein LB. Outcomes after ischemic stroke for hospitals with and without Joint Commission–certified primary stroke centers. Neurology 2011, 76: 1976-1982. PMID: 21543736, PMCID: PMC3109877, DOI: 10.1212/wnl.0b013e31821e54f3.Peer-Reviewed Original ResearchConceptsPrimary stroke centerRisk-standardized mortalityJoint CommissionPSC hospitalsIschemic strokeReadmission ratesStroke centersService Medicare beneficiariesHospital referral regionsIschemic stroke dischargesPSC certificationPatient demographicsComorbid conditionsStudy cohortMortality outcomesNational averagePrimary diagnosisReferral regionsMedicare beneficiariesHierarchical linear regression modelsHospitalStroke dischargesLinear regression modelsLower ratesStroke
2010
Use of Antithrombotic Medications Among Elderly Ischemic Stroke Patients
Lichtman JH, Naert L, Allen NB, Watanabe E, Jones SB, Barry LC, Bravata DM, Goldstein LB. Use of Antithrombotic Medications Among Elderly Ischemic Stroke Patients. Circulation Cardiovascular Quality And Outcomes 2010, 4: 30-38. PMID: 21098780, PMCID: PMC3073519, DOI: 10.1161/circoutcomes.109.850883.Peer-Reviewed Original ResearchConceptsDeep vein thrombosis prophylaxisElderly ischemic stroke patientsIschemic stroke patientsThrombosis prophylaxisAntithrombotic medicationSkilled nursing facilitiesEligible patientsAntithrombotic therapyIschemic strokeAtrial fibrillationStroke patientsNursing facilitiesPatients ages 85 yearsSecondary stroke preventionAge 85 yearsRates of receiptLow treatment ratesRate of treatmentAntiplatelet medicationsStroke preventionEffect of agePatient agePatient characteristicsAntiplatelet drugsMedicare feeVariation in Recovery
Lichtman JH, Lorenze NP, D'Onofrio G, Spertus JA, Lindau ST, Morgan TM, Herrin J, Bueno H, Mattera JA, Ridker PM, Krumholz HM. Variation in Recovery. Circulation Cardiovascular Quality And Outcomes 2010, 3: 684-693. PMID: 21081748, PMCID: PMC3064946, DOI: 10.1161/circoutcomes.109.928713.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung AMI patientsAMI patientsYoung womenHeart diseaseSex differencesExcess mortality riskIschemic heart diseaseRisk stratification modelPsychosocial risk factorsYears of ageQuality of careComparison cohortPrognostic factorsPrognostic importanceAMI populationMyocardial infarctionRisk factorsObservational studyMortality riskHigh riskAMI eventsPatientsAge accountWomenPredictors of Hospital Readmission After Stroke
Lichtman JH, Leifheit-Limson EC, Jones SB, Watanabe E, Bernheim SM, Phipps MS, Bhat KR, Savage SV, Goldstein LB. Predictors of Hospital Readmission After Stroke. Stroke 2010, 41: 2525-2533. PMID: 20930150, PMCID: PMC3021413, DOI: 10.1161/strokeaha.110.599159.Peer-Reviewed Original ResearchConceptsReadmission ratesOvid Evidence-Based Medicine ReviewsReadmission performanceEvidence-Based Medicine ReviewsRisk-adjusted readmission ratesHospital readmission performancePredictors of readmissionPatient-level factorsHospital readmission ratesQuality of careSystem-level factorsComposite outcomeHospital readmissionMedicine ReviewsReadmission riskStroke hospitalizationsCare factorsPatient riskMultivariable modelInclusion criteriaReadmissionStroke definitionsEligible publicationsRisk scoreHospital level