2024
IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccination
Park H, Shin M, Shin J, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee S, Jeon S, You S, Racke M, Bucala R, Kang I. IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccination. EBioMedicine 2024, 103: 105114. PMID: 38640835, PMCID: PMC11041015, DOI: 10.1016/j.ebiom.2024.105114.Peer-Reviewed Original ResearchConceptsCD4<sup>+</sup> T cellsCOVID-19 mRNA vaccinesAntigen-specific CD4<sup>+</sup> T cell responsesT cell responsesPrimary antibody deficiencyCD4<sup>+</sup> T cell responsesT cellsIL-1R1MRNA vaccinesIL-1IgG antibodiesAntigen-specific CD4<sup>+</sup> T cellsCD4+ T cell responsesLevels of IL-1R1Human CD4<sup>+</sup> T cellsIL-1 receptor 1Healthy individualsDose of COVID-19 mRNA vaccineAntigen-specific CD4IL-1R1 expressionT cell immunityRepetitive antigenic stimulationCytokines interleukin (IL)-1Immune response to virusesExpression of IL-1R1
2019
Personality and the risk factors for developing behavioral and psychological symptoms of dementia: a narrative review
Young JJ, Balachandran S, Garg G, Balasubramaniam M, Gupta A, Tampi DJ, Tampi RR. Personality and the risk factors for developing behavioral and psychological symptoms of dementia: a narrative review. Neurodegenerative Disease Management 2019, 9: 107-118. PMID: 30998118, DOI: 10.2217/nmt-2018-0044.Peer-Reviewed Original ResearchAlcohol use disorder: How best to screen and intervene.
Dasarathy J, Young J, Chhatlani A, Raddock M, Tampi R. Alcohol use disorder: How best to screen and intervene. The Journal Of Family Practice 2019, 68: 35-39. PMID: 30724900.Peer-Reviewed Original ResearchConceptsAlcohol intake
2018
Cannabinoids for the treatment of behavioral and psychological symptoms of dementia
Tampi R, Young J, Tampi D. Cannabinoids for the treatment of behavioral and psychological symptoms of dementia. Neurodegenerative Disease Management 2018, 8: 211-213. PMID: 30040030, DOI: 10.2217/nmt-2018-0019.Peer-Reviewed Original Research
2014
A review of the relationship between proinflammatory cytokines and major depressive disorder
Young J, Bruno D, Pomara N. A review of the relationship between proinflammatory cytokines and major depressive disorder. Journal Of Affective Disorders 2014, 169: 15-20. PMID: 25128861, DOI: 10.1016/j.jad.2014.07.032.Peer-Reviewed Original ResearchConceptsMajor depressive disorderProinflammatory cytokinesDepressive disorderCytokine profileSerum levelsIL-6IL-8 serum levelsHeterogeneity of MDDAnti-inflammatory treatmentPathogenesis of depressionAnti-inflammatory therapyElevated proinflammatory cytokinesElevated serum levelsProgression of MDDDevelopment of biomarkersInflammatory hypothesisMDD treatmentCSF levelsDepression medicationsMCP-1Inflammatory processMDD pathogenesisDepressed patientsPossible diagnostic toolAdjuvant properties