2023
Quantification of inter-brain coupling: A review of current methods used in haemodynamic and electrophysiological hyperscanning studies
Hakim U, De Felice S, Pinti P, Zhang X, Noah J, Ono Y, Burgess P, Hamilton A, Hirsch J, Tachtsidis I. Quantification of inter-brain coupling: A review of current methods used in haemodynamic and electrophysiological hyperscanning studies. NeuroImage 2023, 280: 120354. PMID: 37666393, DOI: 10.1016/j.neuroimage.2023.120354.Peer-Reviewed Original ResearchConceptsInter-brain couplingHyperscanning studyFunctional magnetic resonanceBrain imaging modalitiesSocial neuroscienceCognitive mechanismsSocial anxietyBrain couplingCognitive researchSocial interactionHyperscanningMental healthDifferent modalitiesMagnetoencephalographyDevelopmental conditionsElectroencephalographyMore participantsParticipantsAutismNeuroscienceFNIRSAnxietyBrainModalitiesSchizophreniaVolume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group
Groenewold N, Bas-Hoogendam J, Amod A, Laansma M, Van Velzen L, Aghajani M, Hilbert K, Oh H, Salas R, Jackowski A, Pan P, Salum G, Blair J, Blair K, Hirsch J, Pantazatos S, Schneier F, Talati A, Roelofs K, Volman I, Blanco-Hinojo L, Cardoner N, Pujol J, Beesdo-Baum K, Ching C, Thomopoulos S, Jansen A, Kircher T, Krug A, Nenadić I, Stein F, Dannlowski U, Grotegerd D, Lemke H, Meinert S, Winter A, Erb M, Kreifelts B, Gong Q, Lui S, Zhu F, Mwangi B, Soares J, Wu M, Bayram A, Canli M, Tükel R, Westenberg P, Heeren A, Cremers H, Hofmann D, Straube T, Doruyter A, Lochner C, Peterburs J, Van Tol M, Gur R, Kaczkurkin A, Larsen B, Satterthwaite T, Filippi C, Gold A, Harrewijn A, Zugman A, Bülow R, Grabe H, Völzke H, Wittfeld K, Böhnlein J, Dohm K, Kugel H, Schrammen E, Zwanzger P, Leehr E, Sindermann L, Ball T, Fonzo G, Paulus M, Simmons A, Stein M, Klumpp H, Phan K, Furmark T, Månsson K, Manzouri A, Avery S, Blackford J, Clauss J, Feola B, Harper J, Sylvester C, Lueken U, Veltman D, Winkler A, Jahanshad N, Pine D, Thompson P, Stein D, Van der Wee N. Volume of subcortical brain regions in social anxiety disorder: mega-analytic results from 37 samples in the ENIGMA-Anxiety Working Group. Molecular Psychiatry 2023, 28: 1079-1089. PMID: 36653677, PMCID: PMC10804423, DOI: 10.1038/s41380-022-01933-9.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderSubcortical brain regionsAnxiety disordersSAD patientsBilateral putamen volumesSubcortical regionsBrain regionsLinear mixed effects analysisComorbid anxiety disordersSubcortical volumesFamily-wise errorPutamen volumeSAD onsetVolumetric differencesPallidum volumeMixed effects analysisD effect sizesInconsistent findingsLeft putamenEffect sizeFull samplePrevious findingsInternational sampleSignificant interactionLimited convergence
2022
Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder
Fertuck E, Stanley B, Kleshchova O, Mann J, Hirsch J, Ochsner K, Pilkonis P, Erbe J, Grinband J. Rejection Distress Suppresses Medial Prefrontal Cortex in Borderline Personality Disorder. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 8: 651-659. PMID: 36868964, PMCID: PMC10388534, DOI: 10.1016/j.bpsc.2022.11.006.Peer-Reviewed Original ResearchConceptsBorderline personality disorderRejection distressFunctional magnetic resonancePrefrontal cortex responsesCortex responsesPrefrontal cortexPersonality disorderControl participantsWhole-brain responsesNeural responsesFunctional magnetic resonance imagingMagnetic resonance imagingMedial prefrontal cortexHealthy control participantsUnivariate analysisMagnetic resonanceBPD groupResonance imagingNovel functional magnetic resonanceGroup differencesRostromedial prefrontal cortexNeural substratesBrain activityDistressNeural mechanismsNeural correlates of eye contact and social function in autism spectrum disorder
Hirsch J, Zhang X, Noah J, Dravida S, Naples A, Tiede M, Wolf J, McPartland J. Neural correlates of eye contact and social function in autism spectrum disorder. PLOS ONE 2022, 17: e0265798. PMID: 36350848, PMCID: PMC9645655, DOI: 10.1371/journal.pone.0265798.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderDorsal parietal regionsNeural correlatesEye contactLive eyesNeural responsesSpectrum disorderAutism Diagnostic Observation ScheduleUnderlying neural correlatesSocial Responsiveness ScaleGold standard measureCentral diagnostic criterionDiagnostic criteriaDiagnostic biomarkersSRS-2ADOS-2Responsiveness ScaleObservation ScheduleParietal regionsPupillometry dataNeural systemsEyesNatural interactionDisordersCorrelatesAn Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions
Crum J, Zhang X, Noah A, Hamilton A, Tachtsidis I, Burgess PW, Hirsch J. An Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2022, 7: 669-679. PMID: 35144035, PMCID: PMC9271588, DOI: 10.1016/j.bpsc.2022.01.008.Peer-Reviewed Original ResearchConceptsInterpersonal interactionsPrefrontal cortexRostral prefrontal cortexInferior parietal lobuleMental health interventionsNeural underpinningsDysfunctional cognitionsBrain systemsEcological validityPrefrontal systemsParietal lobuleNeural couplingNeuroimaging techniquesVerbal communicationVerbal interactionClinical neuroscienceMental healthCortexClinical situationsClinical settingClinical tasksClinical interactionsParadigmHealth interventionsCognition
2021
Bidirectional Connectivity Between Broca's Area and Wernicke's Area During Interactive Verbal Communication
Ono Y, Zhang X, Noah JA, Dravida S, Hirsch J. Bidirectional Connectivity Between Broca's Area and Wernicke's Area During Interactive Verbal Communication. Brain Connectivity 2021, 12: 210-222. PMID: 34128394, PMCID: PMC9058861, DOI: 10.1089/brain.2020.0790.Peer-Reviewed Original ResearchConceptsWernicke's areaNeural mechanismsBroca's areaDirectional connectivityHealthy adult participantsHemodynamic responseBidirectional connectivityFunctional connectivityNeural modulationBrainNeuronal informationSpeech areasNeural activityAdult participantsBrocaContrast findingsHuman brainImpact statementNeural dynamicsBrain modelFindingsWernicke'sSocial functionGranger causality analysisVerbal condition
2018
Functional connectivity of PAG with core limbic system and laryngeal cortico-motor structures during human phonation
Galgano J, Pantazatos S, Allen K, Yanagihara T, Hirsch J. Functional connectivity of PAG with core limbic system and laryngeal cortico-motor structures during human phonation. Brain Research 2018, 1707: 184-189. PMID: 30500402, PMCID: PMC7434632, DOI: 10.1016/j.brainres.2018.11.040.Peer-Reviewed Original ResearchConceptsPeriaqueductal gray regionPsychophysiological interaction analysisFunctional connectivityDiffusion tensor imaging (DTI) analysisTrend-level evidenceNeural mechanismsBilateral auditory corticesGreater functional connectivityAmygdala couplingWhole-brain resultsDorsomedial prefrontal cortexLimbic systemMotor areaAmygdala clustersAuditory cortexLaryngeal musculatureHealthy adultsPrefrontal cortexNeuroimaging studiesNeural activityVoice disordersStructural connectivityGray regionCortexMovement paradigmCommunication of emotion via drumming: dual-brain imaging with functional near-infrared spectroscopy
Rojiani R, Zhang X, Noah A, Hirsch J. Communication of emotion via drumming: dual-brain imaging with functional near-infrared spectroscopy. Social Cognitive And Affective Neuroscience 2018, 13: 1047-1057. PMID: 30215809, PMCID: PMC6204489, DOI: 10.1093/scan/nsy076.Peer-Reviewed Original ResearchConceptsInternational Affective Picture SystemCommunication of emotionsTemporoparietal junction (TPJ) activationExpression of emotionsSocial neuroscienceNeuroimaging paradigmEmotional contentRight TPJHigh arousalPicture SystemValence measuresNeural responsesNonverbal communicationEmotionsNatural communicationNeural activityCommunication modalitiesJunction activationHuman interactionUnderstudied topicDrummingHemodynamic signalsEffective clinical approachContrast comparisonsTPJA cross-brain neural mechanism for human-to-human verbal communication
Hirsch J, Noah J, Zhang X, Dravida S, Ono Y. A cross-brain neural mechanism for human-to-human verbal communication. Social Cognitive And Affective Neuroscience 2018, 13: 907-920. PMID: 30137601, PMCID: PMC6137318, DOI: 10.1093/scan/nsy070.Peer-Reviewed Original ResearchConceptsSuperior temporal gyrusInteractive brain hypothesisNeural mechanismsSocial interactionBrain hypothesisCanonical language areasHuman verbal communicationNon-interactive conditionDynamic social interactionsObject NamingSocial cuesInterpersonal informationBrain substratesDescription taskTemporal gyrusBroca's areaLanguage areasWernicke's areaNeural activitySubcentral areaVerbal communicationNatural settingsTheoretical frameworkGeneral theoretical frameworkDeoxyhemoglobin signalThe present and future use of functional near‐infrared spectroscopy (fNIRS) for cognitive neuroscience
Pinti P, Tachtsidis I, Hamilton A, Hirsch J, Aichelburg C, Gilbert S, Burgess PW. The present and future use of functional near‐infrared spectroscopy (fNIRS) for cognitive neuroscience. Annals Of The New York Academy Of Sciences 2018, 1464: 5-29. PMID: 30085354, PMCID: PMC6367070, DOI: 10.1111/nyas.13948.Peer-Reviewed Original ResearchConceptsCognitive neuroscienceSocial cognitive neuroscienceCognitive neuroscience researchFunctional magnetic resonance imagingElectroencephalography/magnetoencephalographyPotential of fNIRSNaturalistic environmentNeuroscience researchNeuroscienceNeuroimaging modalitiesBodily movementParticipant populationExperimental settingsMagnetic resonance imagingFNIRSMagnetoencephalographyResonance imagingParticular focusResearch
2015
fMRI Validation of fNIRS Measurements During a Naturalistic Task
Noah JA, Ono Y, Nomoto Y, Shimada S, Tachibana A, Zhang X, Bronner S, Hirsch J. fMRI Validation of fNIRS Measurements During a Naturalistic Task. Journal Of Visualized Experiments 2015, 52116. PMID: 26132365, PMCID: PMC4544944, DOI: 10.3791/52116.Peer-Reviewed Original ResearchConceptsNaturalistic tasksBrain activityVideo game taskTask-related increasesFunctional magnetic resonanceFunctional brain activityFull-body activitiesDance Dance RevolutionFMRI scanningPsychophysical tasksNeural mechanismsGame taskFMRI procedureFNIRS experimentFNIRS measurementsFMRINaturalistic behaviorsFMRI signalsFNIRSSimple fingerTaskParadigmNeural recordingsFindingsBehavior
2014
Negative Blood Oxygen Level Dependent Signals During Speech Comprehension
Moreno D, Schiff ND, Hirsch J. Negative Blood Oxygen Level Dependent Signals During Speech Comprehension. Brain Connectivity 2014, 5: 232-244. PMID: 25412406, PMCID: PMC4432885, DOI: 10.1089/brain.2014.0272.Peer-Reviewed Original ResearchConceptsBlood oxygen level-dependent (BOLD) signalSpeech conditionsLevel-dependent signalBOLD signalSpeech comprehensionResting baselineNatural speechComprehension of speechCanonical language areasLanguage-related tasksNatural speech conditionNegative BOLD responseReceptive languageLanguage tasksPassive listeningComprehension studiesFrontoparietal regionsLanguage areasSame stimuliBOLD responseComprehensionBrain regionsSame speechBrief Report: Anomalous Neural Deactivations and Functional Connectivity During Receptive Language in Autism Spectrum Disorder: A Functional MRI Study
Karten A, Hirsch J. Brief Report: Anomalous Neural Deactivations and Functional Connectivity During Receptive Language in Autism Spectrum Disorder: A Functional MRI Study. Journal Of Autism And Developmental Disorders 2014, 45: 1905-1914. PMID: 25526952, PMCID: PMC4441908, DOI: 10.1007/s10803-014-2344-y.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNegative BOLD responseASD participantsReceptive languageLanguage disabilitySpectrum disorderNeural deactivationInhibitory processesFunctional connectivityFunctional magnetic resonance imagingBlood oxygen level-dependent (BOLD) responseSuperior temporal gyrusFunctional MRI studyLevel-dependent responsesNeural mechanismsPassive listeningTemporal gyrusBOLD responseControl participantsParticipantsLanguageMagnetic resonance imagingExcitatory processesMRI studiesConnectivityAmodal brain activation and functional connectivity in response to high‐energy‐density food cues in obesity
Carnell S, Benson L, Pantazatos SP, Hirsch J, Geliebter A. Amodal brain activation and functional connectivity in response to high‐energy‐density food cues in obesity. Obesity 2014, 22: 2370-2378. PMID: 25098957, PMCID: PMC4224976, DOI: 10.1002/oby.20859.Peer-Reviewed Original ResearchConceptsFunctional connectivityObese individualsFood cuesEffect of obesityLow-ED foodsWhole-brain activationGreater functional connectivityLean womenDifferential neural responsesObesogenic environmentMidbrainExcessive foodVTABrain activationNeural responsesObeseFMRI scanningObesityPutamenCerebellumActivationResponseCue modalityIndividualsWomen
2013
Learning not to Fear: Neural Correlates of Learned Safety
Kong E, Monje FJ, Hirsch J, Pollak DD. Learning not to Fear: Neural Correlates of Learned Safety. Neuropsychopharmacology 2013, 39: 515-527. PMID: 23963118, PMCID: PMC3895233, DOI: 10.1038/npp.2013.191.Peer-Reviewed Original ResearchConceptsSpecific affective disordersNeural correlatesAffective disordersFear responsesNeural mechanismsNeurobiological underpinningsInstances of protectionNeural circuitryTranslational neuroscienceChronic stressBasis of insightsNeuroscienceDisordersAnxietyFearIdentification of episodesUnderpinningsCorrelatesCircuitryPeopleAbilitySymptomsHumansShared space, separate processes: Neural activation patterns for auditory description and visual object naming in healthy adults
Hamberger MJ, Habeck CG, Pantazatos SP, Williams AC, Hirsch J. Shared space, separate processes: Neural activation patterns for auditory description and visual object naming in healthy adults. Human Brain Mapping 2013, 35: 2507-2520. PMID: 23918095, PMCID: PMC4091775, DOI: 10.1002/hbm.22345.Peer-Reviewed Original ResearchConceptsVisual namingVisual objectsAuditory descriptionActivation patternsPosterior temporal activationNeural activation patternsCommon neural substrateTask-related differencesTask-specific regionsPosterior temporal regionsAnterior temporal cortexTypes of tasksCortical stimulation studiesTemporo-parietal regionsTemporal lobe epilepsy patientsHealthy adultsCognitive scientistsStandard univariate analysisNeural processesNeural substratesFunctional neuroimagingCerebral organizationTask specificityTemporal cortexLeft posteriorSleep restriction increases the neuronal response to unhealthy food in normal-weight individuals
St-Onge M, Wolfe S, Sy M, Shechter A, Hirsch J. Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals. International Journal Of Obesity 2013, 38: 411-416. PMID: 23779051, PMCID: PMC3883872, DOI: 10.1038/ijo.2013.114.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingFood stimuliRight insulaUnhealthy foodsUnhealthy food stimuliNormal-weight individualsMiddle temporal gyrusLevel-dependent activityInferior parietal lobuleSuperior frontal gyrusInsula activityFrontal gyrusGreater activationNeural mechanismsTemporal gyrusParietal lobuleFood intakeOrbitofrontal cortexRestricted sleepSame stimuliNeuronal responsesSleep restrictionNeural systemsBrain rewardShort sleep duration
2012
The temporal derivative of expected utility: A neural mechanism for dynamic decision-making
Zhang X, Hirsch J. The temporal derivative of expected utility: A neural mechanism for dynamic decision-making. NeuroImage 2012, 65: 223-230. PMID: 22963852, PMCID: PMC5841235, DOI: 10.1016/j.neuroimage.2012.08.063.Peer-Reviewed Original ResearchConceptsNeural mechanismsBehavioral dataHuman neural correlatesNovel experimental paradigmDistinct neural activitySuperior parietal lobulePosterior cingulate cortexReal-world tasksNeural correlatesFuture rewardsParietal lobuleExperimental paradigmFMRI analysisCingulate cortexNeural activityWorld tasksBrain regionsSupplementary motorCentral gyrusDynamic decision processIndependent manipulationContinuous decisionsDecision processVentral pallidumFMRIGray Matter Abnormalities in Social Anxiety Disorder: Primary, Replication, and Specificity Studies
Talati A, Pantazatos SP, Schneier FR, Weissman MM, Hirsch J. Gray Matter Abnormalities in Social Anxiety Disorder: Primary, Replication, and Specificity Studies. Biological Psychiatry 2012, 73: 75-84. PMID: 22748614, PMCID: PMC3465490, DOI: 10.1016/j.biopsych.2012.05.022.Peer-Reviewed Original ResearchConceptsControl subjectsAnxiety disordersGray matter abnormalitiesHealthy control groupAge 30 yearsDSM-IV criteriaTotal intracranial volumeVoxel-based morphometryGray matter differencesMagnetic resonance imagingBilateral temporal poleLateral orbitofrontal cortexPanic disorder subjectsAngular cortexPD groupFunctional disturbancesNeuroanatomical abnormalitiesSocial anxiety disorderControl groupTemporal poleStructural abnormalitiesLifetime historyResonance imagingSAD groupIntracranial volumeDecoding Unattended Fearful Faces with Whole-Brain Correlations: An Approach to Identify Condition-Dependent Large-Scale Functional Connectivity
Pantazatos SP, Talati A, Pavlidis P, Hirsch J. Decoding Unattended Fearful Faces with Whole-Brain Correlations: An Approach to Identify Condition-Dependent Large-Scale Functional Connectivity. PLOS Computational Biology 2012, 8: e1002441. PMID: 22479172, PMCID: PMC3315448, DOI: 10.1371/journal.pcbi.1002441.Peer-Reviewed Original ResearchConceptsFearful facesEmotional expressionBilateral middle temporal gyrusThreat-related stimuliUnattended fearful facesLarge-scale functional connectivityMultiple functional connectionsFunctional magnetic resonanceWhole-brain patternsMiddle temporal gyrusWhole-brain correlationActive research goalNeutral facesEmotion processingFear perceptionImplicit fearImplicit presentationAngular gyrusChance accuracyTemporal gyrusBrain activityFace presentationPrefrontal cortexParietal regionsFunctional connectivity