2024
Sponsorship of Clinical Trials Related to the Shoulder and Elbow: Trends Over Time and Comparative Analysis of Trial Characteristics by Sponsorship Type
Caruana D, Grauer J. Sponsorship of Clinical Trials Related to the Shoulder and Elbow: Trends Over Time and Comparative Analysis of Trial Characteristics by Sponsorship Type. JAAOS Global Research And Reviews 2024, 8: e23.00257. PMID: 38175673, PMCID: PMC10758529, DOI: 10.5435/jaaosglobal-d-23-00257.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicElbowElbow JointGovernment AgenciesHealth FacilitiesHumansShoulder
2022
Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials
Caruana DL, Gouzoulis MJ, McLaughlin WM, Grauer JN. Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials. Journal Of Shoulder And Elbow Surgery 2022, 31: 1922-1928. PMID: 35398166, DOI: 10.1016/j.jse.2022.02.030.Peer-Reviewed Original ResearchConceptsIndependent predictorsTrial characteristicsClinical trialsTrial terminationOdds of terminationClinical trial completionRetention of participantsResults databaseInterventional studyTrial completionMultivariate analysisAssess reasonsLogistic regressionRecruitment statusTrialsSearch termsParticipant recruitmentPredictorsShoulderIndustry sponsorshipOddsTotalCurrent studyRegistryBlindingAnalysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials
Caruana DL, Kim D, Galivanche AR, David WB, Justen MA, Moushey AM, Sheth AH, Paranjpe MD, Grauer JN. Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials. Clinical Spine Surgery A Spine Publication 2022, 35: e596-e600. PMID: 35351841, DOI: 10.1097/bsd.0000000000001323.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicCross-Sectional StudiesDatabases, FactualHumansOdds RatioRegistriesSpineConceptsClinical trialsTrial terminationTrial characteristicsMultivariate analysisCross-sectional analysisInvestigation of drugsInsufficient accrualResults databaseInterventional studyDetermine predictorsClinical studiesBACKGROUND DATACommon reasonAssess reasonsRecruitment statusTrialsPredictors of terminationSearch termsSpineCompletion ratesRegistryPredictorsStudyTermination
2018
Frequency and Acceptability of Adverse Events After Anterior Cervical Discectomy and Fusion
Wilson JR, Radcliff K, Schroeder G, Booth M, Lucasti C, Fehlings M, Ahmad N, Vaccaro A, Arnold P, Sciubba D, Ching A, Smith J, Shaffrey C, Singh K, Darden B, Daffner S, Cheng I, Ghogawala Z, Ludwig S, Buchowski J, Brodke D, Wang J, Lehman RA, Hilibrand A, Yoon T, Grauer J, Dailey A, Steinmetz M, Harrop JS. Frequency and Acceptability of Adverse Events After Anterior Cervical Discectomy and Fusion. Clinical Spine Surgery A Spine Publication 2018, 31: e270-e277. PMID: 29708891, DOI: 10.1097/bsd.0000000000000645.Peer-Reviewed Original ResearchMeSH KeywordsBack PainCervical VertebraeClinical Trials as TopicDiskectomyHumansNervous System DiseasesPostoperative ComplicationsQualitative ResearchQuality of LifeSpinal FusionConceptsAnterior cervical discectomyAdverse eventsCervical discectomyPrimary specialtyPractice locationAdjacent segment diseaseSpinal cord injuryUS surgeonsWrong-level surgeryFuture quality improvementComplication eventsAcceptable complicationsUncommon complicationEsophageal injuryLevel surgeryCord injurySegment diseaseSpine surgerySurgeon experienceOrthopaedic surgeonsSurgeons' opinionsComplicationsDiscectomyMajority of respondentsSurgeons