2015
Delayed Surgery After Acute Traumatic Central Cord Syndrome Is Associated With Reduced Mortality
Samuel AM, Grant RA, Bohl DD, Basques BA, Webb ML, Lukasiewicz AM, Diaz-Collado PJ, Grauer JN. Delayed Surgery After Acute Traumatic Central Cord Syndrome Is Associated With Reduced Mortality. Spine 2015, 40: 349-356. PMID: 25757037, DOI: 10.1097/brs.0000000000000756.Peer-Reviewed Original ResearchConceptsAcute traumatic central cord syndromeTraumatic central cord syndromeCentral cord syndromeMinor adverse eventsSerious adverse eventsAdverse eventsAssociation of timeCord syndromeNational Trauma Data Bank Research Data SetNational Trauma Data Bank Research DataInjury severityPre-existing comorbidityCharlson Comorbidity IndexPre-existing comorbiditiesInjury Severity ScoreOdds of mortalityMultivariate logistic regressionSpinal cord injurySpinal cord recoveryPotential neurological effectsComorbidity indexEarly surgeryMedical optimizationInpatient mortalitySurgical timing
2007
A Quantitative and Reproducible Method to Assess Cord Compression and Canal Stenosis After Cervical Spine Trauma
Furlan JC, Fehlings MG, Massicotte EM, Aarabi B, Vaccaro AR, Bono CM, Madrazo I, Villanueva C, Grauer JN, Mikulis D. A Quantitative and Reproducible Method to Assess Cord Compression and Canal Stenosis After Cervical Spine Trauma. Spine 2007, 32: 2083-2091. PMID: 17762809, DOI: 10.1097/brs.0b013e318145a91c.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedCervical VertebraeFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNorth AmericaObserver VariationPrognosisReproducibility of ResultsSeverity of Illness IndexSignal Processing, Computer-AssistedSpinal Cord CompressionSpinal Cord InjuriesSpinal StenosisTomography, X-Ray ComputedConceptsMaximum spinal cord compressionTraumatic cervical spinal cord injuryCervical spinal cord injuryMaximum canal compromiseSpinal cord injuryInterclass correlation coefficientCord compressionIntrarater reliabilityAcute traumatic cervical spinal cord injuryTraumatic spinal cord injuryCervical spine traumaSpinal cord compressionT1-weighted MRIT2-weighted MR imagesCanal stenosisCanal compromiseSpine traumaPrognostic valueCord injuryRadiologic parametersCervical spineBACKGROUND DATACT scanMidsagittal MRIInterrater ICC
2004
Pathophysiology and pharmacologic treatment of acute spinal cord injury
Kwon BK, Tetzlaff W, Grauer JN, Beiner J, Vaccaro AR. Pathophysiology and pharmacologic treatment of acute spinal cord injury. The Spine Journal 2004, 4: 451-464. PMID: 15246307, DOI: 10.1016/j.spinee.2003.07.007.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryPathophysiologic processesPharmacologic treatmentNeuroprotective agentsSecondary damageImportant pathophysiologic processSecondary injury cascadePharmacologic therapyAcute treatmentInjury cascadeNeurologic functionNeuroprotective strategiesDevastating injuriesPathophysiologic mechanismsSpecific therapyPathophysiologic eventsSpinal cordHuman trialsPotential therapyInjuryAnimal dataLiterature reviewTherapy