2024
Outcomes After Total Knee Arthroplasty in Patients With Autism: A Retrospective Database Study
Kim L, Zehner K, Halperin S, Grauer J. Outcomes After Total Knee Arthroplasty in Patients With Autism: A Retrospective Database Study. JAAOS Global Research And Reviews 2024, 8: e24.00134. PMID: 39652716, PMCID: PMC11627478, DOI: 10.5435/jaaosglobal-d-24-00134.Peer-Reviewed Original ResearchConceptsElixhauser Comorbidity IndexAdverse eventsTotal knee arthroplasty patientsKnee arthroplasty patientsKaplan-Meier survival analysisInfectious adverse eventsUrinary tract infectionHigher Elixhauser comorbidity indexTKA patientsRetrospective database studyArthroplasty patientsPerioperative precautionsTract infectionsAggregate adverse eventsPearlDiver databaseControl patientsImplant survivalMatched cohortAdverse outcomesRate of revisionComorbidity indexPatientsDatabase studySurvival analysisSpectrum disorderPatients on Antidepressants Are at an Increased Risk of Adverse Events following Total Knee Arthroplasty.
Ratnasamy P, Diatta F, Oghenesume O, Sanchez J, Gouzoulis M, Grauer J. Patients on Antidepressants Are at an Increased Risk of Adverse Events following Total Knee Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2024 PMID: 39637418, DOI: 10.5435/jaaos-d-24-00743.Peer-Reviewed Original ResearchTime of surgeryTotal knee arthroplasty patientsAdverse eventsRevision surgeryTotal knee arthroplastyPatient ageIncreased risk of adverse eventsRisk of adverse eventsElixhauser Comorbidity Index scorePostoperative adverse eventsInferior perioperative outcomesComorbidity Index scoreKnee arthroplastyPerioperative outcomesElixhauser Comorbidity IndexPostoperative outcomesAntidepressant medicationAntidepressantsComorbidity indexMultivariate analysisPatient populationSurgeryIncreased riskLevel IIIPatientsPatients With Diabetes on Sodium-Glucose Cotransporter-2 Inhibitors Undergoing Total Knee Arthroplasty Are at Increased Odds for a Number of Postoperative Adverse Events But Reduced Risk of Transfusion.
Kim L, Wiznia D, Grauer J. Patients With Diabetes on Sodium-Glucose Cotransporter-2 Inhibitors Undergoing Total Knee Arthroplasty Are at Increased Odds for a Number of Postoperative Adverse Events But Reduced Risk of Transfusion. Journal Of The American Academy Of Orthopaedic Surgeons 2024 PMID: 39630933, DOI: 10.5435/jaaos-d-24-00299.Peer-Reviewed Original ResearchSodium-glucose cotransporter 2 inhibitorsDM patientsAdverse eventsDiabetes mellitusTotal knee arthroplastySGLT2i useElixhauser Comorbidity IndexComorbidity indexMultivariate analysisIncidence of blood transfusionReduced risk of transfusionAssociated with multiple complicationsOdds of transfusionUrinary tract infectionAssociated with increased riskPerioperative adverse outcomesRisk of transfusionAssociated with reduced incidenceAcute kidney injuryPostoperative adverse eventsSurgical decision makingControlled DM patientsActive tobacco useGroup of medicationsAssociated with higher oddsImpact of Surgeon Volume on Perioperative Complications and Survival to Total Hip Arthroplasty Following Femoral Head Core Decompression
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Seddio A, Li M, Wiznia D, Grauer J. Impact of Surgeon Volume on Perioperative Complications and Survival to Total Hip Arthroplasty Following Femoral Head Core Decompression. JAAOS Global Research And Reviews 2024, 8: e24.00153. PMCID: PMC11578193, DOI: 10.5435/jaaosglobal-d-24-00153.Peer-Reviewed Original ResearchFemoral head osteonecrosisHip fractureInvasive proceduresCore decompressionHigh-volume surgeon groupImpact of surgeon volumeTotal hip arthroplastyKaplan-Meier survival analysisHigh-volume surgeonsMinimally invasive procedureSurgeon volume categoriesStatistically significant differenceAssess complicationsPerioperative complicationsPostoperative complicationsElixhauser Comorbidity IndexAdult patientsVolume surgeonsTreatment optionsAdverse eventsSurgeon volumeSurgeon groupComorbidity indexMultivariate analysisComplicationsUlcerative Colitis Patients are at Increased Risk for Adverse Events Following Total Hip Arthroplasty
Oghenesume O, Gouzoulis M, Ratnasamy P, Dhodapkar M, Grauer J, Rubin L. Ulcerative Colitis Patients are at Increased Risk for Adverse Events Following Total Hip Arthroplasty. The Journal Of Arthroplasty 2024 PMID: 39515400, DOI: 10.1016/j.arth.2024.10.134.Peer-Reviewed Original ResearchPostoperative adverse eventsAdverse eventsClasses of medicationsElixhauser Comorbidity IndexUlcerative colitisPatient ageTotal hip arthroplastyTotal hip arthroplasty patientsFive-year survivalUlcerative colitis patientsArthroplasty patientsPatient's medication regimenHip arthroplasty patientsDisease ulcerative colitisUC patientsColitis patientsComorbidity indexCorticosteroidsPerioperative periodIncreased riskHip arthroplastyPatientsMedication regimenDisease processMatched groupSemaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Varthi A, Rubio D, Grauer J. Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024 PMID: 39491749, DOI: 10.1016/j.spinee.2024.10.011.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsAdverse eventsPostoperative complicationsT2DM patientsCurrent Procedural TerminologyElixhauser Comorbidity IndexED visitsLumbar fusionHospital readmissionEmergency departmentOdds of postoperative complicationsNinety-day postoperative complicationsImpact of semaglutideOdds of hospital readmissionMonths of surgeryRetrospective cohort studyPostoperative adverse eventsMinor adverse eventsType II diabetes mellitusRisk of type I errorDiagnosis of T2DMII diabetes mellitusYears of ageImproved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization
Seddio A, Wilhelm C, Gouzoulis M, Islam W, Vasudevan R, Halperin S, Rubin L, Medvecky M, Donohue K, Grauer J. Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization. JSES International 2024 DOI: 10.1016/j.jseint.2024.10.006.Peer-Reviewed Original ResearchTotal shoulder arthroplastyBody mass indexT2DM patientsElixhauser Comorbidity IndexMultivariate analysisOdds of surgical site infectionUrinary tract infectionSurgical site infectionAcute kidney injuryType II diabetes mellitusII diabetes mellitusTract infectionsSite infectionClinical benefitPreoperative optimizationCardiac eventsKidney injuryVenous thromboembolismMetformin useAdverse eventsManagement of type II diabetes mellitusMass indexDiabetes mellitusType II diabetesAdverse outcomesContinuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty
Freedman I, Mercier M, Galivanche A, Sandhu M, Hocevar M, Moore H, Grauer J, Rubin L, Li J. Continuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty. Journal Of Pain Research 2024, 17: 3729-3740. PMID: 39559456, PMCID: PMC11572497, DOI: 10.2147/jpr.s462079.Peer-Reviewed Original ResearchContinuous adductor canal blockAdductor canal blockEpidural analgesiaEA patientsNon-home dischargeCanal blockMultivariate analysisIncidence of postoperative adverse eventsPostoperative adverse eventsMorphine equivalentsEpidural anesthesiaAdverse eventsRetrospective analysisHospital lengthProlonged LOSLevel IIIPatientsSteroidsTotal knee arthroplastyAdjuvantTKA patientsLogistic regressionDischarge dispositionAnalgesiaKnee arthroplastyInflammatory bowel disease is associated with greater odds of complications following posterior lumbar fusion and further amplified for patients exposed to biologics
Seddio A, Katsnelson B, Smith-Voudouris J, Gouzoulis M, Day W, Jabbouri S, Vasudevan R, Rubio D, Grauer J. Inflammatory bowel disease is associated with greater odds of complications following posterior lumbar fusion and further amplified for patients exposed to biologics. North American Spine Society Journal (NASSJ) 2024, 100574. DOI: 10.1016/j.xnsj.2024.100574.Peer-Reviewed Original ResearchPosterior lumbar fusionInflammatory bowel diseaseOdds ratioNational Inpatient SampleElixhauser Comorbidity IndexLumbar fusionBowel diseaseKaplan-Meier survival analysisEmergency departmentInflammatory bowel disease patientsLog-rank testMinor adverse eventsNon-IBD patientsIn-hospital dataMultivariate logistic regressionAssociated with greater oddsElevated odds ratiosReoperation rateSurgical complicationsSpine surgeryInferior outcomesPearlDiver databasePost-discharge outcomesAdult patientsAdverse eventsLower Risk of Postoperative Complications and Rotator Cuff Retear Associated with Semaglutide Use in Patients with Type II Diabetes Mellitus Undergoing Arthroscopic Rotator Cuff Repair
Seddio A, Moran J, Gouzoulis M, Garbis N, Salazar D, Grauer J, Jimenez A. Lower Risk of Postoperative Complications and Rotator Cuff Retear Associated with Semaglutide Use in Patients with Type II Diabetes Mellitus Undergoing Arthroscopic Rotator Cuff Repair. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2024 PMID: 39490542, DOI: 10.1016/j.arthro.2024.09.057.Peer-Reviewed Original ResearchArthroscopic rotator cuff repairT2DM patientsRotator cuff retearRotator cuff repairElixhauser Comorbidity IndexAdverse eventsLow risk of postoperative complicationsOdds ratioRisk of postoperative complicationsKaplan-Meier survival analysisUrinary tract infectionSurgical-site infectionCuff repairLog-rank testRetrospective comparative studyAcute kidney injuryMinor adverse eventsType II diabetes mellitusAssociated with decreased oddsMultivariate logistic regressionArthroscopic shoulder proceduresII diabetes mellitusAdministrative billing codesPostoperative complicationsTract infectionsFollowing carpel tunnel release, what factors affect whether patients return to the same or different hand surgeon for a subsequent procedure?
Halperin S, Dhodapkar M, Pathak N, Joo P, Luo X, Grauer J. Following carpel tunnel release, what factors affect whether patients return to the same or different hand surgeon for a subsequent procedure? PLOS ONE 2024, 19: e0312159. PMID: 39436931, PMCID: PMC11495619, DOI: 10.1371/journal.pone.0312159.Peer-Reviewed Original ResearchImpact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisAfter Primary Total Shoulder Arthroplasty, Factors Associated with Returning to the Same Surgeon for Subsequent Total Shoulder Arthroplasty
Gouzoulis M, Halperin S, Seddio A, Wilhelm C, Moran J, Donohue K, Jimenez A, Grauer J. After Primary Total Shoulder Arthroplasty, Factors Associated with Returning to the Same Surgeon for Subsequent Total Shoulder Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e24.00117. PMID: 39401371, PMCID: PMC11473060, DOI: 10.5435/jaaosglobal-d-24-00117.Peer-Reviewed Original ResearchConceptsTotal shoulder arthroplastyShoulder arthroplastyAdverse eventsPrimary total shoulder arthroplastyTotal shoulder arthroplasty patientsAnatomic total shoulder arthroplastyPatient satisfactionDepression diagnosisMinority of patientsPostoperative adverse eventsAssociated with decreased oddsRevision TSAFactors associated with returnSame surgeonContralateral surgeryElixhauser Comorbidity IndexIpsilateral shoulderFemale sexComorbidity indexMultivariate analysisRevision surgeryComorbidity burdenPatientsImprove patient satisfactionSurgeonsComparable Overall Risk of Neurologic Adverse Events Following Cervicothoracic Interlaminar and Transforaminal Epidural Injections: An Analysis of 1.29 Million Patients.
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Vasudevan R, Day W, Ratnasamy P, Rubio D, Grauer J. Comparable Overall Risk of Neurologic Adverse Events Following Cervicothoracic Interlaminar and Transforaminal Epidural Injections: An Analysis of 1.29 Million Patients. Spine 2024 PMID: 39394649, DOI: 10.1097/brs.0000000000005181.Peer-Reviewed Original ResearchNeurological adverse eventsAdverse eventsElixhauser Comorbidity IndexNeurological complicationsOdds ratioEpidural spinal injectionsInterlaminar (ILTransforaminal epidural injectionsAssociated with specific complicationsTransforaminal (TFNerve root injuryRisk of complicationsAssociated with higher odds ratiosMultivariate logistic regressionRisk of neurological adverse eventsHigher odds ratioCervical pathologyEpidural hematomaTF injectionSpinal injectionEpidural injectionSpecific complicationsAdult patientsCase reportComorbidity indexPreoperative Anxiety: An Important Risk Factor of Postoperative Adverse Events and Increased Reoperation Rates in Patients Undergoing Single-Level Anterior Cervical Diskectomy and Fusion
Katsnelson B, Rancu A, Winter A, Grauer J. Preoperative Anxiety: An Important Risk Factor of Postoperative Adverse Events and Increased Reoperation Rates in Patients Undergoing Single-Level Anterior Cervical Diskectomy and Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00204. PMCID: PMC11473058, DOI: 10.5435/jaaosglobal-d-24-00204.Peer-Reviewed Original ResearchRevision surgery ratesAnterior cervical diskectomyAdverse eventsACDF patientsCervical diskectomySurgery ratesSingle-level anterior cervical diskectomyAdverse outcomesPreoperative anxietyCervical spine surgeryIncreased reoperation rateAssociated with adverse eventsFusion (ACDFSingle-level ACDFPostoperative adverse eventsPrevalence of mental health disordersImportant risk factorsMultivariate regression analysisReoperation rateMental health disordersSpine surgerySurgical outcomesElixhauser Comorbidity IndexHistory of anxietySurgical proceduresRisk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients
Ratnasamy P, Diatta F, Allam O, Kauke-Navarro M, Grauer J. Risk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients. JAAOS Global Research And Reviews 2024, 8: e24.00040. PMID: 39392934, PMCID: PMC11469891, DOI: 10.5435/jaaosglobal-d-24-00040.Peer-Reviewed Original ResearchConceptsBehcet's syndromeAdverse eventsTotal knee arthroplastyMultivariate analysisRevision surgeryRisk of postoperative complicationsRisk of perioperative adverse eventsTotal hip arthroplastyLog-rank testElixhauser Comorbidity Index scoreRetrospective cohort studyMultisystem autoimmune disorderPostoperative adverse eventsPerioperative adverse eventsComorbidity Index scoreNational administrative databaseKnee arthroplastyTotal knee arthroplasty patientsPostoperative complicationsNo significant differencePatient ageAutoimmune disordersPerioperative managementSyndrome patientsCohort studyPatients with fibromyalgia have increased risk of 90-day postoperative adverse events following arthroscopic rotator cuff repair
Rancu A, Katsnelson B, Sanchez J, Winter A, Vasudevan R, Grauer J. Patients with fibromyalgia have increased risk of 90-day postoperative adverse events following arthroscopic rotator cuff repair. JSES International 2024 DOI: 10.1016/j.jseint.2024.09.018.Peer-Reviewed Original ResearchRotator cuff repairPostoperative adverse eventsAdverse eventsArthroscopic rotator cuff repairCurrent Procedural TerminologyElixhauser Comorbidity IndexOccurrence of wound dehiscenceEmergency departmentUrinary tract infectionSymptomatic rotator cuff tearsAssociated with increased riskCuff repairLog-rank testYear of surgerySurgical site infectionSevere adverse eventsKaplan-Meier curvesAcute kidney injuryOccurrence of sepsisDeep vein thrombosisMinor adverse eventsRotator cuff repair patientsIndividual adverse eventsOdds of ED utilizationDiagnosis of fibromyalgia90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. 90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study. JAAOS Global Research And Reviews 2024, 8: e24.00069. PMID: 39330875, PMCID: PMC11412709, DOI: 10.5435/jaaosglobal-d-24-00069.Peer-Reviewed Original ResearchConceptsHip fracture surgeryHip fractureGeriatric patientsFracture surgeryAdverse eventsRate of minor adverse eventsCOVID-19 diagnosisWeeks of surgeryMinor adverse eventsTime pointsAssociated with increased oddsComplication rateAssess complicationsCOVID-19 positivityCOVID-19 infectionMultivariate analysisSurgeryComplicationsPatientsDatabase studyReadmission ratesCare algorithmWeeksDiagnosisCOVID-19Goldenhar syndrome associated with increased risk of respiratory failure and reoperations following spinal deformity surgery
Gouzoulis M, Jabbouri S, Seddio A, Grauer J, Tuason D. Goldenhar syndrome associated with increased risk of respiratory failure and reoperations following spinal deformity surgery. Spine Deformity 2024, 1-6. PMID: 39249241, DOI: 10.1007/s43390-024-00963-3.Peer-Reviewed Original ResearchAdolescent idiopathic scoliosisPosterior spinal fusionGoldenhar syndromeAdverse eventsRespiratory failureSpinal fusionDeformity surgeryIncreasing odds of respiratory failureOdds ratioRisk of respiratory failureOdds of respiratory failureIncidence of adverse eventsIncidence of reoperationSpinal deformity surgeryRisk of adverse eventsSevere adverse eventsPostoperative adverse eventsMultivariate logistic regressionAssociated with scoliosisNational sample of patientsSample of patientsBackgroundGoldenhar syndromeSpinal manifestationsElixhauser Comorbidity IndexPearlDiver databaseTotal Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival.
Gillinov S, Modrak M, Park N, Monahan P, Wilhelm C, Lee M, Mahatme R, Fong S, Moran J, Grauer J, Jimenez A. Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival. Clinical Orthopaedics And Related Research® 2024 PMID: 39246053, DOI: 10.1097/corr.0000000000003209.Peer-Reviewed Original ResearchVenous thromboembolic eventsTotal shoulder arthroplastyHemophilia AImplant survivalMatched controlsThromboembolic eventsElixhauser Comorbidity IndexMale patientsAdverse eventsShoulder arthroplastyProsthesis survivalThromboembolic adverse eventsVenous thromboembolic event prophylaxisKaplan-Meier analysisFactor VIII levelsRevers total shoulder arthroplastyIndividual patient basisOdds of postoperative bleedingPostoperative bleedingBleeding complicationsTranexamic acidNinety-dayPatient basisControl cohortComorbidity index