2011
The Molecular and Cellular Basis of Bitter Taste in Drosophila
Weiss LA, Dahanukar A, Kwon JY, Banerjee D, Carlson JR. The Molecular and Cellular Basis of Bitter Taste in Drosophila. Neuron 2011, 69: 258-272. PMID: 21262465, PMCID: PMC3033050, DOI: 10.1016/j.neuron.2011.01.001.Peer-Reviewed Original Research
2007
Two Gr Genes Underlie Sugar Reception in Drosophila
Dahanukar A, Lei YT, Kwon JY, Carlson JR. Two Gr Genes Underlie Sugar Reception in Drosophila. Neuron 2007, 56: 503-516. PMID: 17988633, PMCID: PMC2096712, DOI: 10.1016/j.neuron.2007.10.024.Peer-Reviewed Original ResearchConceptsSubset of sugarsReporter gene expressionSugar-sensing neuronsDouble mutantSugar receptionMolecular basisGenetic analysisGene expressionGr5aDrosophilaReceptor geneSitu hybridizationGenesNeuronsGr64aPrimary receptorTaste receptorsDistinct projectionsReceptorsTemporal dynamicsSugarsMutantsBehavioral responsesLabellumReporter
2001
A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila
Dahanukar A, Foster K, van der Goes van Naters W, Carlson J. A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila. Nature Neuroscience 2001, 4: 1182-1186. PMID: 11704765, DOI: 10.1038/nn765.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsAnimals, Genetically ModifiedBase SequenceBehavior, AnimalCodonDose-Response Relationship, DrugDrosophilaFood, FormulatedGene DeletionGene Expression RegulationGenetic LinkageGTP-Binding ProteinsMaleMutationNeurons, AfferentPhenotypeProtein BiosynthesisReceptors, Cell SurfaceSucroseTasteTrehaloseX ChromosomeConceptsGR geneG protein-coupled receptor genesSugar trehaloseG protein-mediated signalingDrosophila genome databaseTransgenic rescue experimentsProtein-mediated signalingSpecificity of expressionGenome databaseTaste receptorsDifferent mutantsRescue experimentsGenesLarge familyGr5aDrosophilaFunctional evidenceReceptor geneGR receptorsTaste ligandsGustatory neuronsTaste neuronsTrehaloseReceptorsFamily members
2000
Candidate Taste Receptors in Drosophila
Clyne P, Warr C, Carlson J. Candidate Taste Receptors in Drosophila. Science 2000, 287: 1830-1834. PMID: 10710312, DOI: 10.1126/science.287.5459.1830.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAlternative SplicingAmino Acid SequenceAnimalsChemoreceptor CellsDrosophila melanogasterDrosophila ProteinsExonsGene ExpressionGenes, InsectIn Situ HybridizationInsect ProteinsMembrane ProteinsMolecular Sequence DataMultigene FamilyNeurons, AfferentOrgan SpecificityProtein Structure, TertiaryReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionSense OrgansSequence AlignmentTasteConceptsDrosophila genome databaseTransmembrane domain proteinCandidate taste receptorsDomain proteinsDrosophila mutantsDivergent familiesGenome databaseTaste receptorsTissue specificityMolecular mechanismsDiverse familyGustatory organsGenesStructural similarityLabellumBasis of structureTaste signalingProteinTaste neuronsInitial eventFamilyExpressionDrosophilaMutantsReceptors