2015
Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use
Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-oa.Peer-Reviewed Original ResearchConceptsHigh-power fieldMC countChronic diarrheaMast cell countsUnknown etiologyMast cellsCutoff valueMastocytic enterocolitisLeft colonBiopsy resultsClinical utilityDiscriminatory cutoff valuesCell countC-kit stainConsecutive control patientsMast cell stabilizerSpecific cutoff valuesSingle high-power fieldControl patientsConsecutive patientsNormal biopsiesCell stabilizerCharacteristic analysisStudy groupSpecial stains
2009
Mucosal Schwann Cell “Hamartoma”
Gibson JA, Hornick JL. Mucosal Schwann Cell “Hamartoma”. The American Journal Of Surgical Pathology 2009, 33: 781-787. PMID: 19065103, DOI: 10.1097/pas.0b013e31818dd6ca.Peer-Reviewed Original ResearchMeSH KeywordsActinsAgedAged, 80 and overAntigens, CD34Cell DifferentiationCell ProliferationClaudin-1Colonic PolypsColonoscopyColorectal NeoplasmsDiagnosis, DifferentialFemaleGlial Fibrillary Acidic ProteinHamartomaHumansImmunohistochemistryIncidental FindingsIntestinal MucosaMaleMembrane ProteinsMiddle AgedMucin-1Neurofibromatosis 1Neurofilament ProteinsNeuromaProto-Oncogene Proteins c-kitS100 ProteinsSchwann CellsConceptsLamina propriaHistologic featuresGanglion cellsSchwann cellsColorectal polypsNF1 patientsNeurofilament proteinDense eosinophilic cytoplasmGlial fibrillary acidic proteinSolitary colorectal polypsSimilar histologic featuresBland spindle cellsIndistinct cell bordersType 1 neurofibromatosisEpithelial membrane antigenFibrillary acidic proteinSchwann cell proliferationSmooth muscle actinUniform bland spindle cellsRare axonsMucosal biopsiesPositive axonsImmunohistochemical featuresNeural lesionsIntralesional heterogeneity