2017
Clinicopathologic and outcome study of sessile serrated adenomas/polyps with serrated versus intestinal dysplasia
Cenaj O, Gibson J, Odze RD. Clinicopathologic and outcome study of sessile serrated adenomas/polyps with serrated versus intestinal dysplasia. Modern Pathology 2017, 31: 633-642. PMID: 29271414, DOI: 10.1038/modpathol.2017.169.Peer-Reviewed Original ResearchConceptsSessile serrated adenomas/polypsSerrated adenomas/polypsAdenomas/polypsIntestinal dysplasiaConventional adenomasSerrated dysplasiaPrevalence of adenocarcinomaType of dysplasiaHigh-grade lesionsDysplasia-carcinoma sequenceLow-grade dysplasiaNeoplastic precursor lesionsHigh rateDysplasia subtypeControl patientsPathologic featuresMean ageMicrosatellite unstable cancersBiologic featuresInvasive carcinomaPrecursor lesionsNeoplastic lesionsPrevalence ratesOutcome studiesPatients
2015
Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease
Shen J, Gibson JA, Schulte S, Khurana H, Farraye FA, Levine J, Burakoff R, Cerda S, Qazi T, Hamilton M, Srivastava A, Odze RD. Clinical, pathologic, and outcome study of hyperplastic and sessile serrated polyps in inflammatory bowel disease. Human Pathology 2015, 46: 1548-1556. PMID: 26297256, DOI: 10.1016/j.humpath.2015.06.019.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseNeoplastic lesionsHyperplastic polypsFlat dysplasiaIBD patientsBowel diseaseAdenoma-like dysplasiaTraditional serrated adenomasSessile serrated polypsAverage followSurgical resectionClinicopathological featuresColon resectionSporadic adenomasSerrated polypsLower riskSerrated pathwayPatientsSerrated adenomasLesionsDysplasiaAdenoma/AdenocarcinomaResectionAdenomasPerforming Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use
Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing Colonic Mast Cell Counts in Patients With Chronic Diarrhea of Unknown Etiology Has Limited Diagnostic Use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-oa.Peer-Reviewed Original ResearchConceptsHigh-power fieldMC countChronic diarrheaMast cell countsUnknown etiologyMast cellsCutoff valueMastocytic enterocolitisLeft colonBiopsy resultsClinical utilityDiscriminatory cutoff valuesCell countC-kit stainConsecutive control patientsMast cell stabilizerSpecific cutoff valuesSingle high-power fieldControl patientsConsecutive patientsNormal biopsiesCell stabilizerCharacteristic analysisStudy groupSpecial stains
2012
BRAF V600E mutation in papillary thyroid microcarcinoma: a genotype–phenotype correlation
Virk RK, Van Dyke AL, Finkelstein A, Prasad A, Gibson J, Hui P, Theoharis CG, Carling T, Roman SA, Sosa JA, Udelsman R, Prasad ML. BRAF V600E mutation in papillary thyroid microcarcinoma: a genotype–phenotype correlation. Modern Pathology 2012, 26: 62-70. PMID: 22918165, DOI: 10.1038/modpathol.2012.152.Peer-Reviewed Original ResearchConceptsPapillary thyroid microcarcinomaThyroid microcarcinomaPapillary thyroid carcinomaFollicular variantThyroid carcinomaLateral cervical node metastasesOsteoclastic-type giant cellsCervical node metastasisInfiltrative tumor borderGroup of tumorsBRAF V600E mutationClassic nuclear featuresGenotype-phenotype correlationStromal calcificationLymphovascular invasionNode metastasisClinicopathologic featuresLymphocytic infiltrationAggressive featuresTumor sizeCystic changesPapillary microcarcinomaAbsence of mutationsHigh prevalenceMicrocarcinoma