2018
Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling
Yan J, Moreau A, Khodaparast S, Perazzo A, Feng J, Fei C, Mao S, Mukherjee S, Košmrlj A, Wingreen NS, Bassler BL, Stone HA. Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling. Advanced Materials 2018, 30: e1804153. PMID: 30368924, PMCID: PMC8865467, DOI: 10.1002/adma.201804153.Peer-Reviewed Original ResearchConceptsBiofilm removal strategiesMaterial propertiesBiofouling problemsInterfacial propertiesSurface foulingRheological characterizationIndustrial operationsMechanical protectionSurface analysisBiofilm-forming bacterial speciesMultiple surfacesBiofilm-dwelling cellsVibrio cholerae biofilmsSurface-attached communitiesSurfaceRemoval strategiesPropertiesFouling
2017
Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion
Yan J, Nadell CD, Stone HA, Wingreen NS, Bassler BL. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion. Nature Communications 2017, 8: 327. PMID: 28835649, PMCID: PMC5569112, DOI: 10.1038/s41467-017-00401-1.Peer-Reviewed Original ResearchConceptsBiofilm-forming bacterial speciesSurface-attached communitiesVibrio choleraeActive cell growthModel organismsMatrix-producing cellsBacterial lifeNutrient uptakeEnvironmental perturbationsBacterial speciesBacterial cellsPlanktonic cellsSubmerged biofilmsExtracellular matrixCell growthMatrix productionOsmotic pressureBiofilm growthBiofilmsCholeraeCellsPhysical exclusionMatrix crosslinkingOsmotic swellingGrowthEnvironmental fluctuation governs selection for plasticity in biofilm production
Yan J, Nadell CD, Bassler BL. Environmental fluctuation governs selection for plasticity in biofilm production. The ISME Journal: Multidisciplinary Journal Of Microbial Ecology 2017, 11: 1569-1577. PMID: 28338673, PMCID: PMC5520152, DOI: 10.1038/ismej.2017.33.Peer-Reviewed Original ResearchConceptsHuman pathogen Vibrio choleraePlanktonic growthFree-swimming stateBiofilm formationPathogen Vibrio choleraeSurface-attached communitiesWild-type V. choleraeNon-producing mutantsBiofilm growth modeCell-cell interactionsSuch flexible strategiesBiofilm productionHabitat turnoverPhenotypic flexibilityCompetitive fitnessMolecular programsCompetitive abilityEnvironmental fluctuationsPlanktonic phaseWild typeBiofilm conditionsPlanktonic conditionsEcological conditionsNutrient accessBiofilm producers