2018
Risk of Systemic Adverse Events Associated with Intravitreal Anti–VEGF Therapy for Diabetic Macular Edema in Routine Clinical Practice
Maloney MH, Schilz SR, Herrin J, Sangaralingham LR, Shah ND, Barkmeier AJ. Risk of Systemic Adverse Events Associated with Intravitreal Anti–VEGF Therapy for Diabetic Macular Edema in Routine Clinical Practice. Ophthalmology 2018, 126: 1007-1015. PMID: 30292542, DOI: 10.1016/j.ophtha.2018.09.040.Peer-Reviewed Original ResearchConceptsDiabetic macular edemaRoutine clinical practiceSystemic serious adverse eventsMacular laserMajor bleedingCerebrovascular diseaseMyocardial infarctionClinical practiceCause hospitalizationAdverse eventsHazard ratioIntravitreal corticosteroidsAnti-VEGFMacular edemaDME treatmentTreatment of DMEIntravitreal anti-VEGF therapyCox proportional hazards regressionAnti-VEGF pharmacotherapySystemic safety profileCorticosteroid-treated patientsRetrospective cohort studySerious adverse eventsSystemic adverse eventsMacular laser photocoagulation
2013
Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size
Filardo G, Lederle FA, Ballard DJ, Hamilton C, da Graca B, Herrin J, Harbor J, VanBuskirk JB, Johnson GR, Powell JT. Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size. Mayo Clinic Proceedings 2013, 88: 910-919. PMID: 24001483, DOI: 10.1016/j.mayocp.2013.05.014.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, AbdominalAortic RuptureFemaleHumansKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRisk FactorsSex FactorsSurvival AnalysisWatchful WaitingConceptsImmediate open repairAbdominal aortic aneurysmOpen repairSurvival differencesAAA sizeSurvival benefitAortic aneurysmUK Small Aneurysm TrialAsymptomatic abdominal aortic aneurysmLarge abdominal aortic aneurysmSmall asymptomatic abdominal aortic aneurysmsSmall abdominal aortic aneurysmsImmediate endovascular repairNonclinical risk factorsSignificant survival benefitFirst-line managementSignificant survival differenceProportional hazards modelEndovascular repairSurveillance patientsAdjusted analysisStudy cohortAneurysm TrialRecent trialsRisk factors