Jeffrey M Vinocur, MD
Associate Professor of PediatricsCards
About
Research
Publications
2025
Risk of late sudden death after surgery for congenital heart disease.
Needleman J, Whitehill R, Claxton J, McCracken C, Zmora R, Vinocur J, Oster M, Kochilas L. Risk of late sudden death after surgery for congenital heart disease. Cardiology In The Young 2025, 1-7. PMID: 40012309, DOI: 10.1017/s1047951125000277.Peer-Reviewed Original ResearchCongenital heart diseaseSudden cardiac deathSingle-ventricle physiologyCongenital heart surgerySudden cardiac death riskCardiac deathCardiac death riskHeart surgerySingle-ventricleHeart failurePediatric Cardiac Care Consortium RegistryRisk of late sudden deathLeft-to-right shunt lesionsLeft-to-right shuntCongenital heart disease typeMild congenital heart diseaseHeart diseaseLong-term follow-upDeath riskLate sudden deathGeneral populationCardiac death patientsSudden cardiac death patientsYears of ageMortality ratio
2024
Cardiac phenotype in adolescents and young adults with long-chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) deficiency
Elizondo G, Saini A, Gonzalez de Alba C, Gregor A, Harding C, Gillingham M, Vinocur J. Cardiac phenotype in adolescents and young adults with long-chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) deficiency. Genetics In Medicine 2024, 26: 101123. PMID: 38501492, DOI: 10.1016/j.gim.2024.101123.Peer-Reviewed Original ResearchLong-chain 3-hydroxyacyl-CoA dehydrogenase deficiencyLong-chain 3-hydroxyacyl-CoA dehydrogenaseCardiac involvementCardiac arrestMetabolic decompensationCardiac phenotypeDilated cardiomyopathyLong-chain 3-hydroxyacyl-CoA dehydrogenase deficient patientsEpisodes of metabolic decompensationEnd-stage dilated cardiomyopathyOut-of-hospital cardiac arrestAcute cardiac decompensationIn-hospital cardiac arrestFatty acid oxidation disordersLife-threatening arrhythmiasInfantile dilated cardiomyopathySudden cardiac arrestPotential risk factorsCardiac manifestationsCardiac decompensationRestrictive cardiomyopathyRecurrent episodesRetrospective cohortRisk stratificationPeripheral neuropathyReduced kinase function in two ultra‐rare TNNI3K variants in families with congenital junctional ectopic tachycardia
Pham C, Koopmann T, Vinocur J, Blom N, Silbiger V, Mittal K, Bootsma M, Palm K, Clur S, Barge‐Schaapveld D, Hamilton R, Lodder E. Reduced kinase function in two ultra‐rare TNNI3K variants in families with congenital junctional ectopic tachycardia. Clinical Genetics 2024, 106: 37-46. PMID: 38424693, DOI: 10.1111/cge.14504.Peer-Reviewed Original ResearchCongenital junctional ectopic tachycardiaJunctional ectopic tachycardiaK variantEctopic tachycardiaDilated cardiomyopathySupraventricular tachycardiaReduction of kinase activityAssociated with dilated cardiomyopathyFour-generation familyAtrioventricular (AV) nodeInteracting kinasesMissense variantsKinase functionTroponin I-interacting kinaseKinase activityTNNI3KGenetic penetranceTNNI3Variant carriersMultigenerational familiesGenetic testingTroponin ICardiac arrhythmiasTachycardiaVariantsDoubly unusual in double discordance: Appendage-based accessory pathway in congenitally corrected transposition
Beach C, Vinocur J. Doubly unusual in double discordance: Appendage-based accessory pathway in congenitally corrected transposition. HeartRhythm Case Reports 2024, 10: 180-181. PMID: 38496739, PMCID: PMC10943534, DOI: 10.1016/j.hrcr.2023.12.018.Peer-Reviewed Original Research
2023
Lyme Carditis in the Pediatric Population
Beach C, Vinocur J. Lyme Carditis in the Pediatric Population. 2023, 111-119. DOI: 10.1007/978-3-031-41169-4_11.Peer-Reviewed Original ResearchHigh-grade AV blockTemporary transvenous pacingPediatricPediatric patientsLyme carditisHemodynamic instabilityAntibiotic therapyPediatric populationPR prolongationTransvenous pacingAV blockCommon manifestationConduction abnormalitiesTimely administrationCarditisFull recoveryPatientsDiseaseGreat majorityAccompanying increaseTherapyPacingAbnormalitiesSuspicionAdministrationProlongationClinical presentation of calmodulin mutations: the International Calmodulinopathy Registry
Crotti L, Spazzolini C, Nyegaard M, Overgaard M, Kotta M, Dagradi F, Sala L, Aiba T, Ayers M, Baban A, Barc J, Beach C, Behr E, Bos J, Cerrone M, Covi P, Cuneo B, Denjoy I, Donner B, Elbert A, Eliasson H, Etheridge S, Fukuyama M, Girolami F, Hamilton R, Horie M, Iascone M, Jiménez-Jaimez J, Jensen H, Kannankeril P, Kaski J, Makita N, Muñoz-Esparza C, Odland H, Ohno S, Papagiannis J, Porretta A, Prandstetter C, Probst V, Robyns T, Rosenthal E, Rosés-Noguer F, Sekarski N, Singh A, Spentzou G, Stute F, Tfelt-Hansen J, Till J, Tobert K, Vinocur J, Webster G, Wilde A, Wolf C, Ackerman M, Schwartz P. Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry. European Heart Journal 2023, 44: 3357-3370. PMID: 37528649, PMCID: PMC10499544, DOI: 10.1093/eurheartj/ehad418.Peer-Reviewed Original ResearchConceptsClinical presentationPrimary neurological manifestationsCardiac structural abnormalitiesLife-threatening arrhythmia syndromesArrhythmic event rateAbsence of symptomsLife-threatening arrhythmiasSodium channel blockersCongenital heart defectsAntiadrenergic interventionsCardiac eventsHeart failureNeurological manifestationsUnderlying molecular mechanismsDefinitive recommendationsClinical severityChannel blockersObservational studySudden deathIndex caseArrhythmia syndromesHeart defectsPrevalent phenotypeStructural abnormalitiesCurrent managementTranslation of Tools and Techniques from the Adult Electrophysiology World to Pediatric Cardiac Implantable Electronic Devices
Howard T, Vinocur J. Translation of Tools and Techniques from the Adult Electrophysiology World to Pediatric Cardiac Implantable Electronic Devices. Cardiac Electrophysiology Clinics 2023, 15: 515-525. PMID: 37865524, DOI: 10.1016/j.ccep.2023.06.004.Peer-Reviewed Original ResearchWolff-Parkinson-White (WPW) Syndrome
Vinocur J. Wolff-Parkinson-White (WPW) Syndrome. In Clinical Practice 2023, 103-127. DOI: 10.1007/978-3-031-41479-4_6.Peer-Reviewed Original ResearchAsymptomatic patientsRisk stratificationSudden deathCalcium channel blockersEarliest atrial activationAntidromic AVRTAsymptomatic WPWOrthodromic AVRTPharmacologic therapyUncommon manifestationCatheter ablationVariety of manifestationsAtrial fibrillationPathway conductionWolff-ParkinsonAccessory pathwaySerious manifestationsVentricular pacingBidirectional accessory pathwaysCatheter stabilityWhite syndromeAtrial activationFirst lesionPatientsWPW
2022
Life-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review
Lawley C, Tester M, Sanatani S, Prendiville T, Beach C, Vinocur J, Horie M, Uhm J, Khongphatthanayothin A, Ayers M, Starling L, Yoshida Y, Shah M, Skinner J, Turner C. Life-threatening cardiac arrhythmia and sudden death during electronic gaming: An international case series and systematic review. Heart Rhythm 2022, 19: 1826-1833. PMID: 37850595, DOI: 10.1016/j.hrthm.2022.08.003.Peer-Reviewed Original ResearchConceptsInternational case seriesLife-threatening cardiac arrhythmiasCardiac arrhythmiasCase seriesSystematic reviewCatecholaminergic polymorphic ventricular tachycardiaPolymorphic ventricular tachycardiaLong QT syndromeLethal cardiac arrhythmiasCardiac eventsCoronary ischemiaCardiac surgeryVentricular arrhythmiasCardiac arrestSusceptible childrenVentricular tachycardiaVentricular fibrillationSudden deathCardiac conditionsArrhythmic triggersCardiac diagnosisPatientsQT syndromeSusceptible individualsArrhythmiasAblation of ventricular ectopy in complex congenital heart disease: The best of both worlds
Vinocur JM. Ablation of ventricular ectopy in complex congenital heart disease: The best of both worlds. HeartRhythm Case Reports 2022, 8: 548. PMID: 35996706, PMCID: PMC9391403, DOI: 10.1016/j.hrcr.2022.05.021.Commentaries, Editorials and Letters
Academic Achievements & Community Involvement
Clinical Care
Overview
Jeffrey M. Vinocur, MD, is a pediatric and adult congenital cardiologist and electrophysiologist (heart rhythm specialist). He directs the Adult Congenital Electrophysiology Program.
Dr. Vinocur's clinical interests include managing conditions such as heart rhythm problems in fetuses, children, adolescents, and adults including Wolff-Parkinson-White syndrome (WPW), supraventricular tachycardia (SVT), atrial flutter, ventricular tachycardia (VT), and premature beats (PACs and PVCs).
He also specializes in congenital, acquired, and post-surgical heart block (atrioventricular block) and hereditary arrhythmia syndromes including long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), Brugada syndrome, and others.
Dr. Vinocur emphasizes patient/family-centered management with individualized treatment plans and a shared-decision-making approach to exercise. Additionally, he treats cardiomyopathies with heart rhythm involvement, including arrhythmogenic right ventricular cardiomyopathy (ARVC) and hypertrophic cardiomyopathy (HCM) and other medical conditions with heart rhythm involvement, including genetic, neuromuscular, metabolic, and mitochondrial disorders.
For treatment, he offers catheter ablation of arrhythmias, including radiofrequency ablation, cryoablation, and zero-radiation techniques and device therapy for arhythmias such as pacemakers, defibrillators (ICDs), subcutaneous ICDs, and cardiac loop recorders.
As an associate professor of pediatrics at Yale School of Medicine, Dr. Vinocur’s academic interests include many aspects of pediatric and adult congenital cardiology and electrophysiology, with particular emphasis on hereditary arrhythmia syndromes and on quality improvement and outcomes research including the use of multicenter registries, or “big data.”
Dr. Vinocur received his medical training from the University of Pennsylvania. He completed his residency in pediatrics at the University of Connecticut, followed by fellowships in pediatric cardiology at the University of Minnesota and pediatric cardiac electrophysiology at the University of Toronto's Hospital for Sick Children.
Clinical Specialties
Fact Sheets
Adult Congenital Heart Disease
Learn More on Yale MedicinePediatric Congenital Heart Surgery
Learn More on Yale MedicineHeart Arrhythmia
Learn More on Yale MedicineAnesthesia for Atrial Fibrillation
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Yale School of Medicine
Pediatric Cardiology, P.O. Box 208064
New Haven, CT 06520-8064
United States
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Yale Division of Pediatric Cardiology
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Lippard Laboratory of Clinical Investigation (LLCI)
15 York Street
New Haven, CT 06510
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