2020
Pathways to a more peaceful and sustainable world: The transformative power of children in families
Britto PR, Hanöz-Penney S, Ponguta LA, Sunar D, Issa G, Hein SD, do Rosário MC, Almuneef MA, Korucu I, Togo Y, Kurbonov J, Choibekov N, Phan HTT, Fallon NS, Artukoğlu BB, Hartl FJ, Salah R, Fitzpatrick S, Connolly P, Dunne L, Miller S, Pruett K, Leckman JF. Pathways to a more peaceful and sustainable world: The transformative power of children in families. Development And Psychopathology 2020, 33: 409-420. PMID: 32935656, DOI: 10.1017/s0954579420000681.Peer-Reviewed Original Research
2017
A total-population multigenerational family clustering study of autoimmune diseases in obsessive–compulsive disorder and Tourette’s/chronic tic disorders
Mataix-Cols D, Frans E, Pérez-Vigil A, Kuja-Halkola R, Gromark C, Isomura K, Fernández de la Cruz L, Serlachius E, Leckman JF, Crowley JJ, Rück C, Almqvist C, Lichtenstein P, Larsson H. A total-population multigenerational family clustering study of autoimmune diseases in obsessive–compulsive disorder and Tourette’s/chronic tic disorders. Molecular Psychiatry 2017, 23: 1652-1658. PMID: 29133949, PMCID: PMC5951741, DOI: 10.1038/mp.2017.215.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderAutoimmune diseasesChronic tic disorderIndividual autoimmune diseasesThird-degree relativesTic disordersRisk of ADsNational Patient RegisterPatterns of comorbidityFirst-degree relativesPatient RegisterPlacental transmissionNationwide studyBirth cohortCTD casesFamilial clusteringDisordersComorbiditiesPopulation controlsProbandsOCD probandsBiological relativesDiseaseFamilial linkRiskWhat Are the Transgenerational Consequences of Maternal Childhood Adversity and Maternal Stress During Pregnancy?
Leckman JF. What Are the Transgenerational Consequences of Maternal Childhood Adversity and Maternal Stress During Pregnancy? Journal Of The American Academy Of Child & Adolescent Psychiatry 2017, 56: 914-915. PMID: 29096770, DOI: 10.1016/j.jaac.2017.09.421.Peer-Reviewed Original Research
2015
Familial Risks of Tourette Syndrome and Chronic Tic Disorders: A Population-Based Cohort Study
Mataix-Cols D, Isomura K, Pérez-Vigil A, Chang Z, Rück C, Larsson KJ, Leckman JF, Serlachius E, Larsson H, Lichtenstein P. Familial Risks of Tourette Syndrome and Chronic Tic Disorders: A Population-Based Cohort Study. JAMA Psychiatry 2015, 72: 787-793. PMID: 26083307, DOI: 10.1001/jamapsychiatry.2015.0627.Peer-Reviewed Original ResearchConceptsChronic tic disorderFirst-degree relativesTic disordersTourette syndromeFamilial riskSwedish National Patient RegisterNational Patient RegisterSecond-degree relativesRelatives of probandsPopulation-based twin sampleThird-degree relativesFamily studiesCohort studyPatient RegisterFemale patientsSpecialist clinicMAIN OUTCOMESimilar riskGeneral populationPopulation cohortHeritable neuropsychiatric conditionsNeuropsychiatric conditionsSimilar environmental exposuresEnvironmental exposuresDisorders
2012
FAMILY ACCOMMODATION IN PEDIATRIC ANXIETY DISORDERS
Lebowitz ER, Woolston J, Bar‐Haim Y, Calvocoressi L, Dauser C, Warnick E, Scahill L, Chakir AR, Shechner T, Hermes H, Vitulano LA, King RA, Leckman JF. FAMILY ACCOMMODATION IN PEDIATRIC ANXIETY DISORDERS. Depression And Anxiety 2012, 30: 47-54. PMID: 22965863, PMCID: PMC3932435, DOI: 10.1002/da.21998.Peer-Reviewed Original ResearchConceptsChildhood anxiety disordersFamily Accommodation ScaleFamily accommodationAnxiety disordersMeasures of anxietyFamilies of childrenObsessive-compulsive disorderGood internal consistencyTwo-factor solutionAnxious childrenPediatric anxietyAccommodation ScaleSeparation anxietyGreater symptom severityAnxiety symptomsCompulsive disorderDivergent validityFamily routinesAnxietyDiagnostic InterviewPoor treatment outcomesInternal consistencySymptom severityMost parentsFactor analysis
2011
Editorial Perspective: When OCD takes over…the family! Coercive and disruptive behaviours in paediatric obsessive compulsive disorder
Lebowitz ER, Vitulano LA, Mataix‐Cols D, Leckman JF. Editorial Perspective: When OCD takes over…the family! Coercive and disruptive behaviours in paediatric obsessive compulsive disorder. Journal Of Child Psychology And Psychiatry 2011, 52: 1249-1250. PMID: 22022883, DOI: 10.1111/j.1469-7610.2011.02480.x.Peer-Reviewed Original ResearchThe familial association of tourette's disorder and ADHD: The impact of OCD symptoms
O'Rourke JA, Scharf JM, Platko J, Stewart SE, Illmann C, Geller DA, King RA, Leckman JF, Pauls DL. The familial association of tourette's disorder and ADHD: The impact of OCD symptoms. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2011, 156: 553-560. PMID: 21557467, PMCID: PMC3292860, DOI: 10.1002/ajmg.b.31195.Peer-Reviewed Original Research
2008
Oxytocin and cortisol in romantically unattached young adults: Associations with bonding and psychological distress
Gordon I, Zagoory‐Sharon O, Schneiderman I, Leckman JF, Weller A, Feldman R. Oxytocin and cortisol in romantically unattached young adults: Associations with bonding and psychological distress. Psychophysiology 2008, 45: 349-352. PMID: 18266803, DOI: 10.1111/j.1469-8986.2008.00649.x.Peer-Reviewed Original ResearchConceptsPsychological distressHuman social affiliationSelf-report measuresYoung adultsInvolvement of oxytocinAttachment anxietyAdult representationsSocial affiliationOwn parentsSalivary cortisolPlasma oxytocinOT levelsDistressDepressive symptomsAnxietyOxytocinParentsAdultsCognitionRegression analysisLife spanRepresentationAttachmentCortisolExtensive research
2006
A Controlled Family Study of Attention-Deficit/Hyperactivity Disorder and Tourette's Disorder
STEWART SE, ILLMANN C, GELLER DA, LECKMAN JF, KING R, PAULS DL. A Controlled Family Study of Attention-Deficit/Hyperactivity Disorder and Tourette's Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2006, 45: 1354-1362. PMID: 17075358, DOI: 10.1097/01.chi.0000251211.36868.fe.Peer-Reviewed Original Research
1995
A family study of obsessive-compulsive disorder
Pauls DL, Alsobrook JP, Goodman W, Rasmussen S, Leckman JF. A family study of obsessive-compulsive disorder. American Journal Of Psychiatry 1995, 152: 76-84. PMID: 7802125, DOI: 10.1176/ajp.152.1.76.Peer-Reviewed Original ResearchConceptsFirst-degree relativesObsessive-compulsive disorderComparison subjectsSubthreshold obsessive-compulsive disorderAvailable first-degree relativesGilles de la Tourette's syndromeRelatives of probandsLa Tourette's syndromeFamily studiesBest-estimate diagnosesRate of ticsTic disordersFamily historyHigh riskTourette syndromeChronic ticsFemale probandsEarly onsetFamilial typeDisordersUnaffected subjectsProbandsSyndromeStructured interviewsSubjects
1984
On the study of children of parents with affective disorders
Solnit AJ, Leckman JF. On the study of children of parents with affective disorders. American Journal Of Psychiatry 1984, 141: 241-242. PMID: 6691485, DOI: 10.1176/ajp.141.2.241.Peer-Reviewed Original Research
1982
Interaction of biological and psychological factors in the natural history of Tourette syndrome: a paradigm for childhood neuropsychiatric disorders.
Cohen DJ, Detlor J, Shaywitz BA, Leckman JF. Interaction of biological and psychological factors in the natural history of Tourette syndrome: a paradigm for childhood neuropsychiatric disorders. Advances In Neurology 1982, 35: 31-40. PMID: 6959506.Peer-Reviewed Original Research