Gilles de la Tourette syndrome
Robertson MM, Eapen V, Singer HS, Martino D, Scharf JM, Paschou P, Roessner V, Woods DW, Hariz M, Mathews CA, Črnčec R, Leckman JF. Gilles de la Tourette syndrome. Nature Reviews Disease Primers 2017, 3: 16097. PMID: 28150698, DOI: 10.1038/nrdp.2016.97.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderFunctional brain anomaliesObsessive-compulsive disorderChildhood-onset neurodevelopmental disorderPathogenesis of GTSHyperactivity disorderMultiple common risk variantsNeurobiological dataConsiderable social stigmaNeural circuit levelTourette syndromeBehavioral methodsGilles deNeurodevelopmental disordersYears of ageFuture researchSocial stigmaBrain anomaliesPhonic ticsNeuropsychiatric disordersTargeted interventionsClinical phenotypeDisordersFunctional neurosurgeryDe novo mutations