2018
Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial
Fatori D, de Bragança Pereira CA, Asbahr FR, Requena G, Alvarenga PG, de Mathis MA, Rohde LA, Leckman JF, March JS, Polanczyk GV, Miguel EC, Shavitt RG. Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial. Journal Of Anxiety Disorders 2018, 58: 42-50. PMID: 30025255, DOI: 10.1016/j.janxdis.2018.07.002.Peer-Reviewed Original ResearchConceptsGroup cognitive behavioral therapySequential multiple assignmentTreatment failureInitial treatmentBaseline Yale-Brown ObsessiveChildhood OCDEffective initial treatmentProvision of treatmentCompulsive Scale scoresCognitive behavioral therapyAdaptive treatment strategiesYale-Brown ObsessiveSame regimenObsessive-compulsive disorderTreatment strategiesSymptom reductionPrimary analysisScale scoreFluoxetineTime pointsWeeksTreatmentChildrenEffect sizeTrials
2017
A double-blind randomized pilot trial comparing computerized cognitive exercises to Tetris in adolescents with attention-deficit/hyperactivity disorder
Bikic A, Christensen TØ, Leckman JF, Bilenberg N, Dalsgaard S. A double-blind randomized pilot trial comparing computerized cognitive exercises to Tetris in adolescents with attention-deficit/hyperactivity disorder. Nordic Journal Of Psychiatry 2017, 71: 455-464. PMID: 28598701, DOI: 10.1080/08039488.2017.1328070.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderComputerized cognitive exercisesCognitive exercisesHyperactivity disorderComputer game TetrisSignificant intra-group changesADHD symptom measuresSignificant group differencesLarge effect sizesDouble-blind randomized pilot trialBrain trainingSustained attentionCognitive testsGame TetrisMotivation questionnaireHome-based interventionGroup differencesSignificant beneficial effectRandomized pilot trialActive placeboIntra-group changesTetrisAdolescentsEffect sizeBeneficial effects