Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine
Shain S, Gitlin J, Pantazis A, Fine R, Horowitz M, Friedman S, Zelkovic P, Dyer L, Schlussel R, Freyle J, Fang A, Sommer J, Franco I. Management of the refractory nocturnal enuresis patient to desmopressin in a pediatric population: Desmopressin + oxybutynin vs. desmopressin + imipramine. Journal Of Pediatric Urology 2024, 20: 603.e1-603.e8. PMID: 38871547, DOI: 10.1016/j.jpurol.2024.05.024.Peer-Reviewed Original ResearchVancouver Symptom ScoreInternational Children's Continence SocietyWet nightsDesmopressin treatmentCombination therapyResponse rateIntent-to-treat response rateCombination therapy of desmopressinFirst-line medical therapyEfficacy of adjunctive therapyGroup IMPComplete response rateTreated with desmopressinCohort of patientsContinence successPrescribed desmopressinEnuresis patientsMedical therapyNighttime drynessChart reviewAdjunctive therapyConclusion A combinationDesmopressinOxybutyninPediatric populationSize matters: Total testicular volume predicts sperm count in Tanner V varicocele patients
Fang A, Franco I, Pizzuti J, Boroda J, Friedman S, Fine R, Horowitz M, Schlussel R, Landau-Dyer L, Zelkovic P, Freyle J, Sommer J, Gitlin J. Size matters: Total testicular volume predicts sperm count in Tanner V varicocele patients. Journal Of Pediatric Urology 2024, 20: 960-966. PMID: 38876892, DOI: 10.1016/j.jpurol.2024.05.012.Peer-Reviewed Original ResearchNegative predictive valueSemen analysisAbnormal SAPredictive valueSperm countSurgical interventionTesticular volumeRetrospective single-center chart reviewSingle-center chart reviewOdds ratioAppropriateness of surgical interventionLeft-sided varicoceleMotile sperm countAbnormal semen analysisReceiver operating characteristic analysisPrevalence of varicoceleMultivariate logistic regressionTotal testicular volumeYouden's J statisticVaricocele gradeMedian ageChart reviewUltrasound resultsYounger patientsRisk stratification