2018
Assessment and Validation of Syndromic Case definitions for Respiratory Syncytial Virus Testing in a Low Resource Population
Omer SB, Bednarczyk R, Kazi M, Guterman LB, Aziz F, Allen KE, Yildirim I, Ali SA. Assessment and Validation of Syndromic Case definitions for Respiratory Syncytial Virus Testing in a Low Resource Population. The Pediatric Infectious Disease Journal 2018, Publish Ahead of Print: &na;. PMID: 30074977, PMCID: PMC6437080, DOI: 10.1097/inf.0000000000002159.Peer-Reviewed Original ResearchConceptsCommunity-based surveillanceCase definitionRespiratory syncytial virus testingRespiratory syncytial virus infectionSyncytial virus infectionLow-resource populationsStandardized case definitionsSyndromic case definitionsResource-limited settingsVaccine evaluationVirus infectionVirus testingYoung infantsVirus control strategiesModest specificitySurveillanceCyanosisWheezeApneaInfantsInfection
2015
Vaccination, Underlying Comorbidities, and Risk of Invasive Pneumococcal Disease
Yildirim I, Shea KM, Little BA, Silverio AL, Pelton SI. Vaccination, Underlying Comorbidities, and Risk of Invasive Pneumococcal Disease. Pediatrics 2015, 135: 495-503. PMID: 25647674, DOI: 10.1542/peds.2014-2426.Peer-Reviewed Original ResearchMeSH KeywordsBacterial CapsulesChildChild, PreschoolComorbidityFemaleFollow-Up StudiesHumansIncidenceInfantMaleMassachusettsPneumococcal InfectionsPneumococcal VaccinesPopulation SurveillancePrognosisRetrospective StudiesRisk AssessmentRisk FactorsStreptococcus pneumoniaeVaccinationVaccines, ConjugateConceptsInvasive pneumococcal diseasePneumococcal diseaseUnderlying conditionOutcomes of IPDPrevention of IPDChildhood invasive pneumococcal diseasePneumococcal vaccination statusPolysaccharide pneumococcal vaccineYear of diagnosisPrimary care providersCase fatality rateChronic respiratory diseasesImmunocompromising conditionsIPD diagnosisUnderlying comorbiditiesImmunization PracticesIPD casesPneumococcal vaccineVaccination statusConjugate vaccineMassachusetts childrenClinical presentationSerotype distributionHigher hospitalizationClinical data
2010
Pneumococcal serotypes causing pediatric meningitis in Turkey: application of a new technology in the investigation of cases negative by conventional culture
Ceyhan M, Yildirim I, Sheppard C, George R. Pneumococcal serotypes causing pediatric meningitis in Turkey: application of a new technology in the investigation of cases negative by conventional culture. European Journal Of Clinical Microbiology & Infectious Diseases 2010, 29: 289-293. PMID: 20087750, DOI: 10.1007/s10096-009-0853-y.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseasePolymerase chain reactionPneumococcal diseasePneumococcal serotypesCSF samplesAntigen detectionSurveillance of serotypesPneumococcal conjugate vaccinePrior antibiotic useSerotypes/groupsCerebrospinal fluid samplesYears of agePediatric meningitisBacterial meningitisVaccine impactConjugate vaccineActive surveillanceAntibiotic useCommon serotypesQuellung reactionStreptococcus pneumoniaeAge groupsInvestigation of casesSerotype 5Ply gene
2008
A Prospective Study of Etiology of Childhood Acute Bacterial Meningitis, Turkey - Volume 14, Number 7—July 2008 - Emerging Infectious Diseases journal - CDC
Ceyhan M, Yildirim I, Balmer P, Borrow R, Dikici B, Turgut M, Kurt N, Aydogan A, Ecevit C, Anlar Y, Gulumser O, Tanir G, Salman N, Gurler N, Hatipoglu N, Hacimustafaoglu M, Celebi S, Coskun Y, Alhan E, Celik U, Camcioglu Y, Secmeer G, Gur D, Gray S. A Prospective Study of Etiology of Childhood Acute Bacterial Meningitis, Turkey - Volume 14, Number 7—July 2008 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2008, 14: 1089-1096. PMID: 18598630, PMCID: PMC2600347, DOI: 10.3201/eid1407.070938.Peer-Reviewed Original ResearchConceptsAcute bacterial meningitisBacterial meningitisSerogroup WCSF samplesChildhood acute bacterial meningitisHaemophilus influenzae type bInfectious Diseases journal - CDCEtiology of meningitisInfluenzae type bCerebrospinal fluid samplesPCR-positive samplesProspective studyBacterial etiologyMeningococcal diseaseVaccination policyCost of diseaseMeningitisS. pneumoniaeStreptococcus pneumoniaeClinical diagnosisEtiologyN. meningitidisNeisseria meningitidisDiseaseType B