Featured Publications
Integration of expression QTLs with fine mapping via SuSiE.
Zhang X, Jiang W, Zhao H. Integration of expression QTLs with fine mapping via SuSiE. PLOS Genetics 2024, 20: e1010929. PMID: 38271473, PMCID: PMC10846745, DOI: 10.1371/journal.pgen.1010929.Peer-Reviewed Original ResearchConceptsExpression quantitative trait lociGenome-wide association studiesFine-mapping methodsLinkage disequilibriumBody mass indexFine-mappingExpression quantitative trait loci informationGenome-wide association study resultsExpression quantitative trait loci analysisPresence of linkage disequilibriumExternal reference panelGenetic fine-mappingQuantitative trait lociPosterior inclusion probabilitiesInclusion probabilitiesAlzheimer's diseaseExpression QTLsLD patternsComplex traitsCandidate variantsAssociation studiesTrait lociAssociation to causationReference panelFunctional variants
2024
Estimating Cell-Type-Specific Gene Co-Expression Networks from Bulk Gene Expression Data with an Application to Alzheimer’s Disease
Su C, Zhang J, Zhao H. Estimating Cell-Type-Specific Gene Co-Expression Networks from Bulk Gene Expression Data with an Application to Alzheimer’s Disease. Journal Of The American Statistical Association 2024, 119: 811-824. PMID: 39280354, PMCID: PMC11394578, DOI: 10.1080/01621459.2023.2297467.Peer-Reviewed Original Research
2019
O2‐10‐03: LEVERAGING TISSUE SPECIFIC GENE EXPRESSION REGULATION TO IDENTIFY GENES ASSOCIATED WITH ALZHEIMER'S DISEASE
Liu W, Li M, Zhang W, Zhou G, Wu X, Wang J, Zhao H. O2‐10‐03: LEVERAGING TISSUE SPECIFIC GENE EXPRESSION REGULATION TO IDENTIFY GENES ASSOCIATED WITH ALZHEIMER'S DISEASE. Alzheimer's & Dementia 2019, 15: p564-p565. DOI: 10.1016/j.jalz.2019.06.4507.Peer-Reviewed Original Research
2016
O1‐03‐01: Integrative Analysis of Gwas Summary Data and Functional Annotations Highlights Signal Enrichment in Immune‐Related DNA Elements for Late‐Onset Alzheimer’s Disease
Lu Q, Mukherjee S, Crane P, Zhao H. O1‐03‐01: Integrative Analysis of Gwas Summary Data and Functional Annotations Highlights Signal Enrichment in Immune‐Related DNA Elements for Late‐Onset Alzheimer’s Disease. Alzheimer's & Dementia 2016, 12: p176-p177. DOI: 10.1016/j.jalz.2016.06.304.Peer-Reviewed Original Research