Hilary Cain, MD
ProfessorCards
Additional Titles
Director of Clinical Activities, Pulmonary Section, VA CT Healthcare System, West Haven
Director, Medical Intensive Care Unit, VA CT Healthcare System, West Haven
Director, Pulmonary Function Laboratory, VA CT Healthcare System, West Haven
Contact Info
Pulmonary, Critical Care & Sleep Medicine
PO Box 208057, 300 Cedar Street
New Haven, CT 06520-8057
United States
About
Titles
Professor
Director of Clinical Activities, Pulmonary Section, VA CT Healthcare System, West Haven; Director, Medical Intensive Care Unit, VA CT Healthcare System, West Haven; Director, Pulmonary Function Laboratory, VA CT Healthcare System, West Haven
Appointments
Pulmonary, Critical Care & Sleep Medicine
ProfessorPrimary
Other Departments & Organizations
- Chronic Obstructive Pulmonary Disease (COPD) Program
- Internal Medicine
- Pulmonary, Critical Care & Sleep Medicine
- Yale Ventures
Education & Training
- Fellow
- Yale University School of Medicine (1996)
- Chief Resident
- Columbia-Presbyterian Medical Center (1993)
- Resident/Intern
- Columbia-Presbyterian Medical Center (1992)
- MD
- New York Medical College (1988)
Research
Research at a Glance
Yale Co-Authors
Jeffrey Kravetz, MD
Julia Shi, MD, FACP
Kathleen Akgün, MD, MS
Lloyd Friedman, MD
Lori Bastian, MD, MPH
Lynn Tanoue, MD, MBA
Publications
2025
The Association Between Sex and Lung Cancer Screening Adherence to Follow-Up in a Cohort of Veterans
Bernstein E, Bade B, DeRycke E, Lerz K, Zeghlache R, Rose M, Kravetz J, Farmer M, Bastian L, Akgün K, Cain H. The Association Between Sex and Lung Cancer Screening Adherence to Follow-Up in a Cohort of Veterans. Journal Of Women's Health 2025 PMID: 40045919, DOI: 10.1089/jwh.2024.0780.Peer-Reviewed Original ResearchConceptsLung cancer screeningFemale veteransLung-RADSRates of nonadherencePrimary careUnited States Preventive Services Task Force guidelinesAdherence to lung cancer screeningCancer screening adherenceLung-RADS 1Lung-RADS scoreLung-RADS 3Associated with greater nonadherenceTask Force guidelinesCohort of veteransFollow-upFollow-up recommendationsLogistic regression modelsScreening adherenceCancer screeningReduce disparitiesForce guidelinesRetrospective cohort studySubstance use disordersSocioeconomic statusScreening program
2007
IL-18 Is Induced and IL-18 Receptor α Plays a Critical Role in the Pathogenesis of Cigarette Smoke-Induced Pulmonary Emphysema and Inflammation
Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA. IL-18 Is Induced and IL-18 Receptor α Plays a Critical Role in the Pathogenesis of Cigarette Smoke-Induced Pulmonary Emphysema and Inflammation. The Journal Of Immunology 2007, 178: 1948-1959. PMID: 17237446, DOI: 10.4049/jimmunol.178.3.1948.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsChronic obstructive lung diseaseObstructive lung diseaseIL-18Wild-type miceCigarette smokeLung diseasePulmonary emphysemaIL-18RalphaPathogenesis of CSEffects of CSAir-exposed miceIL-18 pathwayIL-18 receptor αIL-18R signalingTh1 inflammationPulmonary macrophagesEpithelial apoptosisReceptor αInflammationPotent stimulatorEmphysemaCaspase-1MiceCritical roleElevated levels
2006
High Rate of Negative Results of Tuberculin and QuantiFERON Tests Among Individuals With a History of Positive Skin Test Results
Friedman LN, Nash ER, Bryant J, Henry S, Shi J, D'Amato J, Khaled GH, Russi MB, O'Connor PG, Edberg SC, Pisani MA, Cain HC, Tanoue L, Weissman DN. High Rate of Negative Results of Tuberculin and QuantiFERON Tests Among Individuals With a History of Positive Skin Test Results. Infection Control And Hospital Epidemiology 2006, 27: 436-441. PMID: 16671022, DOI: 10.1086/503690.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsQuantiFERON-TB testTuberculin skin testPrevious tuberculin skin testTST statusInitial tuberculin skin testPositive tuberculin skin testSecond tuberculin skin testPositive skin test resultsExperienced healthcare workersNegative TST resultsTST-negative groupSkin test resultsTST protocolWhole blood assaysNegative resultsPositive resultsTuberculosis exposureImmunocompetent subjectsQuantiFERON testSkin testTST resultsMedical recordsInduration diameterHealthcare workersHigh risk
Others
- Cain HC. Drug-induced Pulmonary Disease: Non-chemotherapeutic agents. Fishman's Pulmonary Diseases and Disorders. Chapter 59. Ed. Fishman A, et. al. 2007.Peer-Reviewed Original Research
News & Links
Get In Touch
Contacts
Pulmonary, Critical Care & Sleep Medicine
PO Box 208057, 300 Cedar Street
New Haven, CT 06520-8057
United States
Locations
VA Connecticut Healthcare
Academic Office
950 Campbell Avenue
West Haven, CT 06516
Appointments
203.932.5711 x2208