2020
Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients
Miccio JA, Talcott WJ, Jairam V, Park HS, Yu JB, Leapman MS, Johnson SB, King MT, Nguyen PL, Kann BH. Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients. Prostate Cancer And Prostatic Diseases 2020, 24: 414-422. PMID: 32989262, DOI: 10.1038/s41391-020-00291-3.Peer-Reviewed Original ResearchConceptsProstate cancer-specific survivalLow-risk prostate cancerExternal beam radiotherapyTreatment selection biasOverall survivalRadical prostatectomyProstate cancerOS differenceLow-risk prostate cancer patientsCancer-specific survivalEnd Results (SEER) databaseProstate cancer patientsClinical trial designEffectiveness researchComparative effectiveness researchPropensity-score matchingMethodsThe SurveillanceTreatment guidelinesResults databaseEntire cohortResultsA totalCancer patientsTreatment modalitiesNational registryPatient managementNational trends in the management of patients with positive surgical margins at radical prostatectomy
Ghabili K, Park HS, Yu JB, Sprenkle PC, Kim SP, Nguyen KA, Ma X, Gross CP, Leapman MS. National trends in the management of patients with positive surgical margins at radical prostatectomy. World Journal Of Urology 2020, 39: 1141-1151. PMID: 32562045, DOI: 10.1007/s00345-020-03298-6.Peer-Reviewed Original ResearchConceptsAndrogen deprivation therapyPositive surgical marginsUse of ADTPost-prostatectomy radiation therapyRadiation therapySurgical marginsRadical prostatectomyInitial courseNode-negative prostate cancerPost-operative radiation therapyMultivariable logistic regression modelNational Cancer DatabaseAdverse pathologic featuresManagement of patientsPost-operative managementLogistic regression modelsDeprivation therapySurgical cancersPrimary endpointRT useSecondary endpointsPathologic characteristicsPathologic featuresUninsured statusCancer Database
2014
Reply to ‘Meta-analysis procedure for the effect of statin on the recurrence of prostate cancer’ by T. Kawada
Park H, Schoenfeld J, Mucci L. Reply to ‘Meta-analysis procedure for the effect of statin on the recurrence of prostate cancer’ by T. Kawada. Annals Of Oncology 2014, 25: 543-544. PMID: 24419238, DOI: 10.1093/annonc/mdt565.Peer-Reviewed Original Research
2013
Statins and prostate cancer recurrence following radical prostatectomy or radiotherapy: a systematic review and meta-analysis
Park HS, Schoenfeld JD, Mailhot RB, Shive M, Hartman RI, Ogembo R, Mucci LA. Statins and prostate cancer recurrence following radical prostatectomy or radiotherapy: a systematic review and meta-analysis. Annals Of Oncology 2013, 24: 1427-1434. PMID: 23508824, PMCID: PMC3660083, DOI: 10.1093/annonc/mdt077.Peer-Reviewed Original ResearchMeSH KeywordsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleNeoplasm Recurrence, LocalProstatectomyProstatic NeoplasmsConceptsRecurrence-free survivalPrimary treatment modalityLocalized prostate cancerEffect of statinsRadical prostatectomy patientsProstate cancer recurrenceHazard ratioProstatectomy patientsTreatment modalitiesRadical prostatectomyCancer recurrenceProstate cancerProstate cancer patientsOncologic outcomesDefinitive treatmentRT patientsCancer patientsEmbase databasesEligible studiesStatinsPatientsSystematic reviewRadiotherapyBeneficial effectsSystematic search