2004
Sex and Age Differences in Lipoprotein Subclasses Measured by Nuclear Magnetic Resonance Spectroscopy: The Framingham Study
Freedman D, Otvos J, Jeyarajah E, Shalaurova I, Cupples L, Parise H, D’Agostino R, Wilson P, Schaefer E. Sex and Age Differences in Lipoprotein Subclasses Measured by Nuclear Magnetic Resonance Spectroscopy: The Framingham Study. Clinical Chemistry 2004, 50: 1189-1200. PMID: 15107310, DOI: 10.1373/clinchem.2004.032763.Peer-Reviewed Original ResearchConceptsLipoprotein concentrationsCHD riskLipoprotein subclassesCoronary heart disease riskSex differencesLipoprotein particlesHeart disease riskFramingham Offspring StudyLipoprotein particle sizeLarge HDL particlesHDL particle sizeConcentration of triglyceridesSize of VLDLFrozen plasma samplesHDL cholesterolLDL cholesterolFramingham StudySubclass concentrationsSubclass profileLarge LDLOffspring StudyConcentration of lipidsHDL particlesMagnetic resonance spectroscopyFemale differences
2003
Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function
Rutter M, Parise H, Benjamin E, Levy D, Larson M, Meigs J, Nesto R, Wilson P, Vasan R. Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function. Circulation 2003, 107: 448-454. PMID: 12551870, DOI: 10.1161/01.cir.0000045671.62860.98.Peer-Reviewed Original ResearchConceptsGlucose tolerance groupInsulin resistanceLV massHOMA-IRGlucose toleranceGlucose intoleranceTolerance groupAbnormal glucose tolerance groupNormal glucose tolerance groupFramingham Study subjectsAbnormal glucose toleranceGlucose tolerance categoriesLeft ventricular hypertrophyBody mass indexLarge community-based sampleLV wall thicknessCommunity-based sampleHeart failureVentricular hypertrophyLA sizeMass indexReferral biasMyocardial infarctionTolerance statusStudy subjects
2002
Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience
Wilson P, D'Agostino R, Sullivan L, Parise H, Kannel W. Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience. JAMA Internal Medicine 2002, 162: 1867-1872. PMID: 12196085, DOI: 10.1001/archinte.162.16.1867.Peer-Reviewed Original ResearchConceptsAge-adjusted relative riskBody mass indexCoronary heart diseasePopulation attributable riskRelative riskCardiovascular diseaseCardiovascular sequelaeAngina pectorisExcess weightAttributable riskHeart diseaseOverweight statusRisk factorsCardiovascular disease risk factorsHighest population-attributable riskNew cardiovascular diseaseDisease risk factorsFramingham Heart Study participantsNormal-weight personsDisease end pointsNew hypertensionCardiovascular riskDiabetes mellitusPrimary outcomeMass index