2007
Associations of Plasma Natriuretic Peptide, Adrenomedullin, and Homocysteine Levels With Alterations in Arterial Stiffness
Levy D, Hwang S, Kayalar A, Benjamin E, Vasan R, Parise H, Larson M, Wang T, Selhub J, Jacques P, Vita J, Keyes M, Mitchell G. Associations of Plasma Natriuretic Peptide, Adrenomedullin, and Homocysteine Levels With Alterations in Arterial Stiffness. Circulation 2007, 115: 3079-3085. PMID: 17533184, DOI: 10.1161/circulationaha.106.652842.Peer-Reviewed Original ResearchConceptsN-terminal atrial natriuretic peptideCarotid-femoral pulse wave velocityB-type natriuretic peptidePulse wave velocityAtrial natriuretic peptideCarotid-radial pulse wave velocityCentral pulse pressurePlasma natriuretic peptidesNatriuretic peptideArterial stiffnessHomocysteine levelsPulse pressureFramingham Heart StudyHeart StudyPlasma N-terminal atrial natriuretic peptideDiastolic blood pressureMean arterial pressureCarotid pulse pressureArterial wall stiffnessForward pressure waveArterial pressureCentral systolicBlood pressureHomocysteine concentrationsCardiovascular disease
2005
Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus
Wilson P, D’Agostino R, Parise H, Sullivan L, Meigs J. Metabolic Syndrome as a Precursor of Cardiovascular Disease and Type 2 Diabetes Mellitus. Circulation 2005, 112: 3066-3072. PMID: 16275870, DOI: 10.1161/circulationaha.105.539528.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseMetabolic syndromeCardiovascular diseaseRelative riskAge-adjusted relative riskType 2 diabetes mellitusPopulation attributable risk estimatesNew cardiovascular diseaseMetabolic syndrome traitsMiddle-aged adultsDiabetes mellitusIncident casesHeart diseaseNew T2DMT2DMType 2SyndromeEvent ratesRisk estimatesDiseaseSyndrome traitsMellitusWomenMenRisk
2002
Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience
Wilson P, D'Agostino R, Sullivan L, Parise H, Kannel W. Overweight and Obesity as Determinants of Cardiovascular Risk: The Framingham Experience. JAMA Internal Medicine 2002, 162: 1867-1872. PMID: 12196085, DOI: 10.1001/archinte.162.16.1867.Peer-Reviewed Original ResearchConceptsAge-adjusted relative riskBody mass indexCoronary heart diseasePopulation attributable riskRelative riskCardiovascular diseaseCardiovascular sequelaeAngina pectorisExcess weightAttributable riskHeart diseaseOverweight statusRisk factorsCardiovascular disease risk factorsHighest population-attributable riskNew cardiovascular diseaseDisease risk factorsFramingham Heart Study participantsNormal-weight personsDisease end pointsNew hypertensionCardiovascular riskDiabetes mellitusPrimary outcomeMass index