2023
Severe aortic stenosis detection by deep learning applied to echocardiography
Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisReclassification of moderate aortic stenosis based on data-driven phenotyping of hemodynamic progression
Cho I, Kim W, Kim S, Ko K, Seong Y, Kim D, Seo J, Shim C, Ha J, Mori M, Gupta A, You S, Hong G, Krumholz H. Reclassification of moderate aortic stenosis based on data-driven phenotyping of hemodynamic progression. Scientific Reports 2023, 13: 6694. PMID: 37095171, PMCID: PMC10125992, DOI: 10.1038/s41598-023-33683-1.Peer-Reviewed Original ResearchConceptsRapid progression groupModerate aortic stenosisAortic valve replacementSlow progression groupAortic stenosisProgression groupHemodynamic progressionRapid progressionMore rapid progressionLatent class trajectory modelingTransthoracic echocardiography studyBetween-group differencesData-driven phenotypingPressure gradient measurementAVR ratesModerate ASCause mortalityValve replacementEchocardiography studyAtrial fibrillationTTE studiesEchocardiographic dataRisk factorsPredictive valuePatients
2021
Trends in Transcatheter and Surgical Aortic Valve Replacement Among Older Adults in the United States
Mori M, Gupta A, Wang Y, Vahl T, Nazif T, Kirtane AJ, George I, Yong CM, Onuma O, Kodali S, Geirsson A, Leon MB, Krumholz HM. Trends in Transcatheter and Surgical Aortic Valve Replacement Among Older Adults in the United States. Journal Of The American College Of Cardiology 2021, 78: 2161-2172. PMID: 34823659, DOI: 10.1016/j.jacc.2021.09.855.Peer-Reviewed Original Research
2016
The Core Value of Cost-Effectiveness Analyses∗
Dhruva SS, Krumholz HM. The Core Value of Cost-Effectiveness Analyses∗. Journal Of The American College Of Cardiology 2016, 67: 39-41. PMID: 26764064, PMCID: PMC5459408, DOI: 10.1016/j.jacc.2015.11.013.Peer-Reviewed Original Research
2015
Hospital Variation in Outcomes for Transcatheter Aortic Valve Replacement Among Medicare Beneficiaries, 2011 to 2013
Murugiah K, Wang Y, Desai NR, Nuti SV, Krumholz HM. Hospital Variation in Outcomes for Transcatheter Aortic Valve Replacement Among Medicare Beneficiaries, 2011 to 2013. Journal Of The American College Of Cardiology 2015, 66: 2678-2679. PMID: 26670069, PMCID: PMC5459372, DOI: 10.1016/j.jacc.2015.10.008.Peer-Reviewed Original Research
2008
ACC/AHA 2008 Guideline Update on Valvular Heart Disease: Focused Update on Infective Endocarditis
Nishimura RA, Carabello BA, Faxon DP, Freed MD, Lytle BW, O'Gara PT, O'Rourke RA, Shah PM, Bonow RO, Carabello BA, Chatterjee K, de Leon AC, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O'Gara PT, O'Rourke RA, Otto CM, Shah PM, Shanewise JS, Smith SC, Jacobs AK, Buller CE, Creager MA, Ettinger SM, Krumholz HM, Kushner FG, Lytle BW, Nishimura RA, Page RL, Tarkington LG, Yancy CW. ACC/AHA 2008 Guideline Update on Valvular Heart Disease: Focused Update on Infective Endocarditis. Catheterization And Cardiovascular Interventions 2008, 72: e1-e12. PMID: 18671249, DOI: 10.1002/ccd.21751.Peer-Reviewed Original Research