2012
Analysis of lipolysis underlying lactation in the tsetse fly, Glossina morsitans
Attardo GM, Benoit JB, Michalkova V, Yang G, Roller L, Bohova J, Takáč P, Aksoy S. Analysis of lipolysis underlying lactation in the tsetse fly, Glossina morsitans. Insect Biochemistry And Molecular Biology 2012, 42: 360-370. PMID: 22509523, PMCID: PMC3561780, DOI: 10.1016/j.ibmb.2012.01.007.Peer-Reviewed Original ResearchConceptsSimultaneous knockdownLipid reservesLarval productionAdipokinetic hormoneEarly larval developmentLate larval instarsTsetse fliesLipid metabolic pathwaysBrummer lipaseLarval nourishmentViviparous reproductionLipid metabolismIndividual knockdownTsetse fecundityKnockdown approachFemale lifespanHormone-receptor systemLarval developmentTranscript levelsAKHRLarval instarsMetabolic pathwaysStarvation experimentsKnockdownOocyte development
2009
Interactions between mutualist Wigglesworthia and tsetse peptidoglycan recognition protein (PGRP-LB) influence trypanosome transmission
Wang J, Wu Y, Yang G, Aksoy S. Interactions between mutualist Wigglesworthia and tsetse peptidoglycan recognition protein (PGRP-LB) influence trypanosome transmission. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 12133-12138. PMID: 19587241, PMCID: PMC2715537, DOI: 10.1073/pnas.0901226106.Peer-Reviewed Original ResearchConceptsImmune deficiencyPGRP-LBHost immune responsePeptidoglycan recognition proteinsAnti-protozoal activityTsetse's abilityImmune responseInfection susceptibilityHost immunityExpression correlatesNormal adultsInfectionHost susceptibilityAntimicrobial peptidesParasitized adultsTrypanosome infectionAdult tsetseRecognition proteinsLimited exposureAdultsForeign microbesRNA interferencePathway functionActivationSusceptibility