2018
Esophageal Varices
Jakab S, Garcia-Tsao G. Esophageal Varices. 2018, 195-208. DOI: 10.1007/978-3-319-98506-0_15.Peer-Reviewed Educational MaterialsVariceal hemorrhageEsophageal varicesComplications of cirrhosisEsophageal variceal hemorrhageScreening/surveillanceSecondary prophylaxisVariceal bleedingLiver diseaseTreatment optionsCurrent recommendationsHigh riskCirrhosisPrevention strategiesVaricesComplicationsHemorrhagePatientsProphylaxisBleedingMortalityDiseaseEVHProgressionSeverity
2017
Management of Portal Hypertension
Garcia‐Tsao G, Abraldes J. Management of Portal Hypertension. 2017, 304-335. DOI: 10.1002/9781119251316.ch12.Peer-Reviewed Educational MaterialsComplications of cirrhosisPortal hypertensionVariceal hemorrhagePortal pressure gradientInferior vena cavaObjective of treatmentGastroesophageal varicesPortal pressurePathological increaseVena cavaPortal veinCommon causeCirrhosisHypertensionComplicationsHemorrhageMost studiesVaricesDecompensationCavaPrimary and secondary prophylaxis of esophageal variceal bleeding
Jangouk P, Garcia-Tsao G. Primary and secondary prophylaxis of esophageal variceal bleeding. Techniques And Innovations In Gastrointestinal Endoscopy 2017, 19: 84-89. DOI: 10.1016/j.tgie.2017.03.004.Peer-Reviewed Educational MaterialsHepatic venous pressure gradientPortal hypertensionVariceal hemorrhageHigh riskComplications of cirrhosisSignificant portal hypertensionVenous pressure gradientDevelopment of varicesEsophageal variceal bleedingIsolated complicationSecondary prophylaxisCompensated cirrhosisDirect complicationsVariceal bleedingClinical decompensationPortal pressureEsophageal varicesCompensated stageChronic conditionsCirrhosisVaricesComplicationsHemorrhageDecompensationPatients
2016
Introduction and Survey Results
Garcia-Tsao G, Ripoll C, Augustin S, Reiberger T, Albillos A, Moreau R, Salerno F, Abraldes J. Introduction and Survey Results. 2016, 303-309. DOI: 10.1007/978-3-319-23018-4_30.Peer-Reviewed Original ResearchComplications of cirrhosisRecurrent variceal hemorrhageVariceal hemorrhageDifferent prognostic stagesEndpoints of trialsPresence of varicesInvestigation of patientsCompensated patientsCurrent therapiesSpecific therapyDifferent prognosisPrognostic stageHemorrhageCirrhosisPatientsComplicationsTherapyDifferent efficacyVaricesDecompensationPrognosisRecurrenceConsensus Statements: Preventing Recurrent Variceal Hemorrhage and Other Decompensating Events
Abraldes J, Albillos A, Augustin S, Moreau R, Reiberger T, Ripoll C, Salerno F, Garcia-Tsao G. Consensus Statements: Preventing Recurrent Variceal Hemorrhage and Other Decompensating Events. 2016, 365-367. DOI: 10.1007/978-3-319-23018-4_36.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2011
Management: Cirrhotic Portal Hypertension
Lim J, Garcia-Tsao G. Management: Cirrhotic Portal Hypertension. 2011, 165-181. DOI: 10.1007/978-1-4419-8327-5_11.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPortal hypertensionVariceal hemorrhageAcute variceal hemorrhageCirrhotic portal hypertensionBetter risk stratificationNovel pharmacotherapeutic agentsGastroesophageal varicesPortal pressureRisk stratificationMain complicationsNoninvasive markerPharmacotherapeutic agentsIndividualized careHypertensionVaricesHemorrhageSignificant mortalityCirrhosisSignificant improvementProphylaxisComplicationsPatientsRecurrenceMortality
2009
Pharmacological versus endoscopic therapy in the prevention of variceal hemorrhage: And the winner is…
Bosch J, Garcia‐Tsao G. Pharmacological versus endoscopic therapy in the prevention of variceal hemorrhage: And the winner is…. Hepatology 2009, 50: 674-677. PMID: 19714716, DOI: 10.1002/hep.23164.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2007
A pilot project examining the predicted preferences of patients and physicians in the primary prophylaxis of variceal hemorrhage
Longacre AV, Imaeda A, Garcia‐Tsao G, Fraenkel L. A pilot project examining the predicted preferences of patients and physicians in the primary prophylaxis of variceal hemorrhage. Hepatology 2007, 47: 169-176. PMID: 17935182, PMCID: PMC2674014, DOI: 10.1002/hep.21945.Peer-Reviewed Original ResearchConceptsEndoscopic variceal ligationProcedure-related bleedingVariceal hemorrhagePrimary prophylaxisPreferences of patientsRoute of administrationSexual dysfunctionFirst-line therapyShortness of breathIndividual patient preferencesUntreated patientsEsophageal varicesVariceal ligationPrimary preventionPatient preferencesRisk of fatigueTreatment preferencesProphylaxisSide effectsHemorrhagePatientsBleedingPhysiciansFuture guidelinesHypotension
2006
Session 2: Predictive Models in Portal Hypertension
Garcia‐Tsao G, D'Amico G, Abraldes J, Schepis F, Merli M, Kim W, Christensen E. Session 2: Predictive Models in Portal Hypertension. 2006, 47-102. DOI: 10.1002/9780470988831.ch4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2001
Propranolol for the prevention of first esophageal variceal hemorrhage: A lifetime commitment?
Abraczinskas D, Ookubo R, Grace N, Groszmann R, Bosch J, Garcia‐Tsao G, Richardson C, Matloff D, Rodés J, Conn H. Propranolol for the prevention of first esophageal variceal hemorrhage: A lifetime commitment? Hepatology 2001, 34: 1096-1102. PMID: 11731997, DOI: 10.1053/jhep.2001.29305.Peer-Reviewed Original ResearchConceptsVariceal hemorrhageBeta blockersVariceal bleedingPrimary preventionFirst esophageal variceal hemorrhageWithdrawal of propranololOutcomes of patientsPlacebo-controlled trialEsophageal variceal hemorrhageGroup of patientsOriginal study populationUntreated populationBlocker therapyIndefinite administrationPlacebo groupPortal hypertensionProphylactic therapyProspective studyCumulative survivalProtective effectStudy populationHemorrhagePatientsPropranololBlockers
1998
Portal hypertension
Garcia-Tsao G. Portal hypertension. Current Opinion In Gastroenterology 1998, 14: 256-264. DOI: 10.1097/00001574-199805000-00012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsComplications of cirrhosisPortal hypertensionHepatic insufficiencySpontaneous bacterial peritonitisInsufficiency contributesVariceal hemorrhageCirrhotic patientsBacterial peritonitisLive diseaseHypertensionMajor syndromesCirrhosisComplicationsInsufficiencyVaricesPeritonitisAscitesHemorrhagePatientsSyndromeDisease
1997
Portal hypertension
Garcia-Tsao G. Portal hypertension. Current Opinion In Gastroenterology 1997, 13: 263-270. DOI: 10.1097/00001574-199705000-00013.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsComplications of cirrhosisPortal hypertensionHepatic insufficiencyChronic liver diseaseSpontaneous bacterial peritonitisInsufficiency contributesVariceal hemorrhageCirrhotic patientsPortosystemic encephalopathyBacterial peritonitisLiver diseaseHypertensionMajor syndromesCirrhosisComplicationsEnd stageInsufficiencyVaricesPeritonitisAscitesHemorrhagePatientsEncephalopathyPathophysiologySyndromeFurther evidence in favor of pharmacological portal pressure reduction in the prevention of variceal hemorrhage
García-Tsao G. Further evidence in favor of pharmacological portal pressure reduction in the prevention of variceal hemorrhage. Gastroenterology 1997, 112: 1770-1771. PMID: 9136864, DOI: 10.1016/s0016-5085(97)70067-2.Peer-Reviewed Original Research
1995
Variceal Hemorrhage
Navarro V, Garcia-Tsao G. Variceal Hemorrhage. Critical Care Clinics 1995, 11: 391-414. PMID: 7788538, DOI: 10.1016/s0749-0704(18)30073-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsVariceal bleedingVariceal hemorrhageFirst variceal bleedingHigh recurrence ratePortal hypertensionBalloon tamponadePharmacologic therapyPortal pressureShunt surgeryActive hemorrhageRecurrence rateBlood flowTherapeutic avenuesHigh mortalityHemorrhageBleedingPreventionHypertensionTamponadeSclerotherapyComplicationsSurgeryRelative effectivenessTherapyMortality
1990
Surgical treatment of hemorrhage of esophageal varices secondary to thrombosis of the portal vein.
Orozco-Zepeda H, Takahashi T, Angel Mercado M, García-Tsao G, Hernández-Ortiz J. Surgical treatment of hemorrhage of esophageal varices secondary to thrombosis of the portal vein. Revista De Gastroenterología De México 1990, 55: 215-9. PMID: 2091189.Peer-Reviewed Original ResearchConceptsHemorrhagic portal hypertensionSugiura procedurePortal hypertensionAssociated liver diseasePortal vein thrombosisProtein C deficiencyActuarial survivalOperative deathsSurgical treatmentVein thrombosisEsophageal varicesLiver diseaseMean ageSurgical stagePortal veinC deficiencyPatientsHypertensionThrombosisEPVTVaricesHemorrhageCasesYearsDisease
1989
Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo‐controlled clinical trial
Bosch J, Groszmann R, García‐Pagán J, Terés J, García‐Tsao G, Navasa M, Mas A, Rodés J. Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: A placebo‐controlled clinical trial. Hepatology 1989, 10: 962-968. PMID: 2511136, DOI: 10.1002/hep.1840100612.Peer-Reviewed Original ResearchConceptsTransdermal nitroglycerinVariceal hemorrhageVariceal bleedingPlacebo-controlled clinical trialActive variceal bleedingEffectiveness of vasopressinDouble-blind techniqueSlow-release preparationHospital mortalityTransfusion requirementsRecurrent bleedingBalloon tamponadeCirrhotic patientsEmergency surgeryVasopressin infusionClinical trialsDefinitive controlDrug combinationsTotal doseNitroglycerinBleedingHemorrhagePatientsInitial controlVasopressin
1985
Portal pressure, presence of gastroesophageal varices and variceal bleeding
Garcia‐Tsao G, Groszmann R, Fisher R, Conn H, Atterbury C, Glickman M. Portal pressure, presence of gastroesophageal varices and variceal bleeding. Hepatology 1985, 5: 419-424. PMID: 3873388, DOI: 10.1002/hep.1840050313.Peer-Reviewed Original ResearchConceptsHepatic vein pressure gradientSmall varicesCirrhotic patientsPortal pressureLarge varicesSize of varicesHepatic vein catheterizationOccurrence of hemorrhagePortal pressure measurementsAlcoholic cirrhosisGastroesophageal varicesVariceal bleedingEsophagogastric varicesVariceal sizeVein catheterizationVaricesPatientsStandardized measurementsHgPressure measurementsCirrhosisBleedingCatheterizationHemorrhageEndoscopy