Relaxin Positively Regulates Matrix Metalloproteinase Expression in Human Lower Uterine Segment Fibroblasts Using a Tyrosine Kinase Signaling Pathway
Palejwala S, Stein D, Weiss G, Monia B, Tortoriello D, Goldsmith L. Relaxin Positively Regulates Matrix Metalloproteinase Expression in Human Lower Uterine Segment Fibroblasts Using a Tyrosine Kinase Signaling Pathway. Endocrinology 2001, 142: 3405-3413. DOI: 10.1210/en.142.8.3405.Peer-Reviewed Original ResearchTissue inhibitor of metalloproteinase-1Matrix metalloproteinase expressionPhorbol-12-myristate-13-acetate-Tissue inhibitorReceptor tyrosine kinase inhibitorsMetalloproteinase-1Protein expressionMatrix metalloproteinasesMetalloproteinase expressionMRNA levelsEffects of relaxinTyrosine kinase inhibitorsCervical connective tissueExpression of matrix metalloproteinasesRegulation of matrix metalloproteinasesTyrosine kinase receptorsSignaling pathwayPreterm deliveryIn vitro modelTyrosine kinase signaling pathwaysKinase inhibitorsRelaxin actionRelaxin receptorKinase signaling pathwayKinase receptors