2024
Investigating muscle coordination patterns with Granger causality analysis in protrusive motion from tagged and diffusion MRI
Park H, Xing F, Stone M, Kang H, Liu X, Zhuo J, Fels S, Reese T, Wedeen V, Fakhri G, Prince J, Woo J. Investigating muscle coordination patterns with Granger causality analysis in protrusive motion from tagged and diffusion MRI. JASA Express Letters 2024, 4: 095201. PMID: 39240196, PMCID: PMC11384280, DOI: 10.1121/10.0028500.Peer-Reviewed Original Research
2021
4D magnetic resonance imaging atlas construction using temporally aligned audio waveforms in speech
Xing F, Jin R, Gilbert I, Perry J, Sutton B, Liu X, Fakhri G, Shosted R, Woo J. 4D magnetic resonance imaging atlas construction using temporally aligned audio waveforms in speech. The Journal Of The Acoustical Society Of America 2021, 150: 3500-3508. PMID: 34852570, PMCID: PMC8580575, DOI: 10.1121/10.0007064.Peer-Reviewed Original ResearchConceptsAudio waveformTemporal domain informationMulti-subject dataAtlas constructionMutual information measureMR image datasetsImage datasetsTarget domainDomain informationPost-processing methodImage sequencesTemporal alignmentSpatiotemporal alignmentMatching patternsInformation measuresImage dataSquare errorAligned volumesAlignment mapOverall score increaseMR technologyCross-correlationDeformable registrationSpeechImagesSpeech intelligibility loss due to amyotrophic lateral sclerosis: the effect of tongue movement reduction on vowel and consonant acoustic features
Rong P, Usler E, Rowe L, Allison K, Woo J, Fakhri G, Green J. Speech intelligibility loss due to amyotrophic lateral sclerosis: the effect of tongue movement reduction on vowel and consonant acoustic features. Clinical Linguistics & Phonetics 2021, 35: 1091-1112. PMID: 33427505, DOI: 10.1080/02699206.2020.1868021.Peer-Reviewed Original ResearchConceptsTarget wordsIntelligence declineSpeech intelligibilityPredictors of speech intelligibilityDysarthria secondary to amyotrophic lateral sclerosisMotor performanceHealthy controlsReduced speech intelligibilityAcoustic featuresPhonetic distinctionsSpeech soundsRobust predictorsTongue movementDisease-related changesSpeech intelligibility declinesAmyotrophic lateral sclerosisTongue dynamicsMeasurement typesReduced rangeImpaired tongue movementMovement reductionWordsTongue bladeVowelsSpeech
2020
Motion correction for PET data using subspace-based real-time MR imaging in simultaneous PET/MR
Marin T, Djebra Y, Han P, Chemli Y, Bloch I, Fakhri G, Ouyang J, Petibon Y, Ma C. Motion correction for PET data using subspace-based real-time MR imaging in simultaneous PET/MR. Physics In Medicine And Biology 2020, 65: 235022. PMID: 33263317, PMCID: PMC7985095, DOI: 10.1088/1361-6560/abb31d.Peer-Reviewed Original ResearchConceptsPositron emission tomography reconstructionMotion-corrected PET reconstructionsPET reconstructionMotion-corrected PET imagesIrregular respiratory motionMotion fieldMotion correction methodMotion correction approachIrregular motion patternsUndersampled k-space dataImage quality of positron emission tomographyQuality of positron emission tomographyMotion patternsLow-rank characteristicsRespiratory motionContrast-to-noise ratioEstimated motion fieldSurrogate signalsMotion correctionK-space dataImage qualityReal-time MR imagingSimultaneous PET/MRMotion artifact reductionPET/MR scanners
2019
Body motion detection and correction in cardiac PET: Phantom and human studies
Sun T, Petibon Y, Han P, Ma C, Kim S, Alpert N, Fakhri G, Ouyang J. Body motion detection and correction in cardiac PET: Phantom and human studies. Medical Physics 2019, 46: 4898-4906. PMID: 31508827, PMCID: PMC6842053, DOI: 10.1002/mp.13815.Peer-Reviewed Original ResearchConceptsList-mode dataMotion-compensated image reconstructionMotion correctionCenter of massPET list-mode dataMotion correction methodMotion detectionMotion estimationImage reconstructionPatient body motionDegrade image qualityNonrigid registrationImage qualityMotion transformationCoincident distributionBody motion detectionCardiac positron emission tomographyBack-projection techniqueCovariance matrixImage volumesBody motionPositron emission tomographyBack-projectionReference framePhantomAtlas-Based Tongue Muscle Correlation Analysis From Tagged and High-Resolution Magnetic Resonance Imaging.
Xing F, Stone M, Goldsmith T, Prince J, El Fakhri G, Woo J. Atlas-Based Tongue Muscle Correlation Analysis From Tagged and High-Resolution Magnetic Resonance Imaging. Journal Of Speech Language And Hearing Research 2019, 62: 2258-2269. PMID: 31265364, PMCID: PMC6808360, DOI: 10.1044/2019_jslhr-s-18-0495.Peer-Reviewed Original ResearchConceptsInternal tongue musclesFloor of mouthMagnetic resonance imagingHigh-resolution magnetic resonance imagingMuscle pairsTongue musclesRehabilitation strategiesSpeech sound productionResonance imagingCoordination patternsSpeech motor controlMuscle locationDisease populationMotion of muscleMotor controlIntersubjective behaviorsManually labeled masksMuscleGlossectomy patientsExtrinsic tongue musclesControl subjectsBloc movementFunctional lossPatientsMotion patternsDifferentiating post-cancer from healthy tongue muscle coordination patterns during speech using deep learning
Woo J, Xing F, Prince J, Stone M, Green J, Goldsmith T, Reese T, Wedeen V, Fakhri G. Differentiating post-cancer from healthy tongue muscle coordination patterns during speech using deep learning. The Journal Of The Acoustical Society Of America 2019, 145: el423-el429. PMID: 31153323, PMCID: PMC6530633, DOI: 10.1121/1.5103191.Peer-Reviewed Original Research
2016
Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR
Petibon Y, Guehl N, Reese T, Ebrahimi B, Normandin M, Shoup T, Alpert N, Fakhri G, Ouyang J. Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR. Physics In Medicine And Biology 2016, 62: 326-343. PMID: 27997375, PMCID: PMC5241952, DOI: 10.1088/1361-6560/aa5087.Peer-Reviewed Original ResearchConceptsSimultaneous PET-MRPET myocardial perfusion imagingMyocardial perfusion imagingPoint spread functionPoint-spread function correctionUngated dataMotion correctionPET-MRPartial volume effectsApparent wall thicknessMyocardial blood flowPartial volume effect correctionMR-based motion correctionMotion fieldPET-MR scannersPoint spread function modelPET dataPerfusion imagingImage qualityImpact of motionDynamic myocardial perfusion imagingAttenuation mapNon-rigid registrationAbsolute myocardial blood flowUngated images
2015
Accelerated acquisition of tagged MRI for cardiac motion correction in simultaneous PET‐MR: Phantom and patient studies
Huang C, Petibon Y, Ouyang J, Reese T, Ahlman M, Bluemke D, El Fakhri G. Accelerated acquisition of tagged MRI for cardiac motion correction in simultaneous PET‐MR: Phantom and patient studies. Medical Physics 2015, 42: 1087-1097. PMID: 25652521, PMCID: PMC4312342, DOI: 10.1118/1.4906247.Peer-Reviewed Original ResearchConceptsPET motion correctionMotion correctionSimultaneous PET-MRTMR dataPET list-mode dataPET-MRList-mode dataCardiac motion correctionPET-MR scannersImage qualityParallel imagingAcquisition timePET imagingRespiratory motionCompressive sensingMotion fieldAttenuation correctionDefect contrastModerate acceleration factorsDegradation of image qualityTagged MRCardiac phantomLong acquisition timesPhantomAccurate motion field
2014
Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging
Petibon Y, Huang C, Ouyang J, Reese T, Li Q, Syrkina A, Chen Y, Fakhri G. Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging. Medical Physics 2014, 41: 042503. PMID: 24694156, PMCID: PMC3971824, DOI: 10.1118/1.4868458.Peer-Reviewed Original ResearchConceptsPoint spread function modelRespiratory motionPoint spread functionPET-MR scannersPencil-beam navigator echoesPET-MRMeasurement of respiratory motionPSF modelRespiratory motion correctionDetector blur effectsModel respiratory motionLung-liver interfacePatient studiesLesion contrastSimultaneous PET-MRSource of image degradationWhole-body PET imagingPET reconstruction algorithmMoving lesionsPhantom experiment resultsPET eventsContrast recoveryNavigator echoesIterative reconstruction processMotion correctionMR‐based motion correction for PET imaging using wired active MR microcoils in simultaneous PET‐MR: Phantom study
Huang C, Ackerman J, Petibon Y, Brady T, Fakhri G, Ouyang J. MR‐based motion correction for PET imaging using wired active MR microcoils in simultaneous PET‐MR: Phantom study. Medical Physics 2014, 41: 041910. PMID: 24694141, PMCID: PMC3978416, DOI: 10.1118/1.4868457.Peer-Reviewed Original ResearchConceptsMotion correctionMR-based motion correctionStatic phantom dataPET quantitative accuracyPET-MRPET-MR scannersSimultaneous PET-MRHoffman phantomList-modePositron emission tomography imagingPET reconstructionBrain positron emission tomographyIterative PET reconstructionPhantom dataPhantomQuantitative accuracyIndependent noise realizationsImage contrastNoise realizationsHead motionPET dataPositron emission tomographyStatic referenceBrain PET scansMotion artifacts
2013
Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study
Petibon Y, Ouyang J, Zhu X, Huang C, Reese T, Chun S, Li Q, Fakhri G. Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study. Physics In Medicine And Biology 2013, 58: 2085-2102. PMID: 23470288, PMCID: PMC3657754, DOI: 10.1088/0031-9155/58/7/2085.Peer-Reviewed Original ResearchConceptsContrast recoveryDetector point spread functionPartial volume effectsK-spaceMotion compensationB-spline registrationLesion-detection studiesCardiac motion compensationPET-MR scannersSimultaneous PET-MRPET contrastIterative reconstruction frameworkPoint spread functionMotion correctionPET countsNon-rigid B-spline registrationCardiac phantomPSF modelPET-MRMotion deblurringReconstruction frameworkSystem matrixCardiac PETSpread functionDefect detectionMagnetic Resonance-Based Motion Correction for Positron Emission Tomography Imaging
Ouyang J, Li Q, Fakhri G. Magnetic Resonance-Based Motion Correction for Positron Emission Tomography Imaging. Seminars In Nuclear Medicine 2013, 43: 60-67. PMID: 23178089, PMCID: PMC3508789, DOI: 10.1053/j.semnuclmed.2012.08.007.Peer-Reviewed Original ResearchConceptsMotion correctionClinical whole-body PET scannersMotion-corrected PET imagesWhole-body PET scannerPET motion correctionNonrigid image registration algorithmAcquired MR imagesRespiratory motionImage registration algorithmPET scannerSimultaneous PET/magnetic resonancePET reconstructionSimultaneous PET/MRPatient motionImage qualityIterative PET reconstructionPET/MR studiesPET/magnetic resonanceAttenuating mediaImage artifactsRegistration algorithmSpatial resolutionReconstruction algorithmPositron emission tomographyMR imaging techniques
2012
MRI-Based Nonrigid Motion Correction in Simultaneous PET/MRI
Chun Y, Reese T, Ouyang J, Guerin B, Catana C, Zhu X, Alpert N, Fakhri G. MRI-Based Nonrigid Motion Correction in Simultaneous PET/MRI. Journal Of Nuclear Medicine 2012, 53: 1284-1291. PMID: 22743250, PMCID: PMC4077320, DOI: 10.2967/jnumed.111.092353.Peer-Reviewed Original ResearchConceptsChannelized Hotelling observerMotion correctionDetection signal-to-noise ratioSignal-to-noise ratioMRI-based motion correctionRespiratory motion correctionMotion-corrected reconstructionOrdered-subsets expectation maximization algorithmNonrigid motion correctionChannelized Hotelling observer studyPET image qualityNonrigid image registration methodCoincidence dataDeformable phantomRespiratory gatingReduce radiation doseDynamic phantomImage registration methodReduced signal-to-noise ratioSimultaneous PET/MRICost of increased noiseHotelling observerPhantomAttenuation measurementsRabbit studies
2011
Nonrigid PET motion compensation in the lower abdomen using simultaneous tagged‐MRI and PET imaging
Guérin B, Cho S, Chun S, Zhu X, Alpert N, Fakhri G, Reese T, Catana C. Nonrigid PET motion compensation in the lower abdomen using simultaneous tagged‐MRI and PET imaging. Medical Physics 2011, 38: 3025-3038. PMID: 21815376, PMCID: PMC3125080, DOI: 10.1118/1.3589136.Peer-Reviewed Original ResearchConceptsPET-MRI acquisitionsMotion correctionPET motion compensationPET motion correctionRespiratory motion correctionMotion-corrected reconstructionMotion correction strategiesWhole-body PET studiesSignal-to-noise ratioPET reconstruction algorithmDeformable phantomNCAT phantomEffects of motionAttenuation mapDetected coincidencesPET-MRIGated framesBrain scannerSimulations of tumorsSignal-to-noisePhantomSusceptibility artifactsReconstruction algorithmPhase domainsNonrigid deformation