2023
Higher circulating cortisol is associated with amyloidogenesis in post‐menopausal women: The Framingham Heart Study
Salardini A, Zilli E, Himali J, Gonzales M, Himali D, Ghosh S, McGrath E, Buckley R, Satizabal C, Johnson K, Decarli C, Fakhri G, Vasan R, Seshadri S. Higher circulating cortisol is associated with amyloidogenesis in post‐menopausal women: The Framingham Heart Study. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.080594.Peer-Reviewed Original ResearchFramingham Heart StudyHeart StudyProspective cohort studyCross sectional studyPostmenopausal womenCognitively normal individualsPost-menopausal womenSectional studyAPOE4 statusAPOE4-positiveLongitudinal cohortSuperior temporal sulcusCortisol levelsMenopausal statusSecondary outcomesAlzheimer's diseaseAssociated with amyloidogenesisCortisol dysregulationBaseline plasma cortisolMorning plasma cortisolTertileFraminghamWomenAssess interactionsProgression of Alzheimer's disease
2003
MRI-Guided SPECT Perfusion Measures and Volumetric MRI in Prodromal Alzheimer Disease
El Fakhri G, Kijewski M, Johnson K, Syrkin G, Killiany R, Becker J, Zimmerman R, Albert M. MRI-Guided SPECT Perfusion Measures and Volumetric MRI in Prodromal Alzheimer Disease. JAMA Neurology 2003, 60: 1066-1072. PMID: 12925361, DOI: 10.1001/archneur.60.8.1066.Peer-Reviewed Original ResearchConceptsRostral anterior cingulateCaudal anterior cingulateMagnetic resonance imagingAnterior cingulateSuperior temporal sulcusPosterior cingulateBasal forebrainTemporal hornEntorhinal cortexTemporal sulcusGroup differencesMemory problemsNondemented patientsFollow-upQuantitative single-photon emissionProdromal phase of Alzheimer's diseaseReceiver operating characteristic curve analysisYears of follow-upAlzheimer's diseasePhase of Alzheimer's diseaseCharacteristic curve analysisVolumetric magnetic resonance imagingMagnetic resonance imaging analysisMagnetic resonance imaging measuresSPECT analysis