2007
Fast Monte Carlo based joint iterative reconstruction for simultaneous SPECT imaging
Ouyang J, Fakhri G, Moore S. Fast Monte Carlo based joint iterative reconstruction for simultaneous SPECT imaging. Medical Physics 2007, 34: 3263-3272. PMID: 17879789, DOI: 10.1118/1.2756601.Peer-Reviewed Original ResearchConceptsMC-JOSEMEnergy windowFast Monte CarloSignal-to-noise ratioScatter correction methodOrdered-subsets expectation-maximizationMonte CarloOrdered-subsets expectation-maximization algorithmIterative reconstruction algorithmPrimary photonsReconstruction algorithmPhoton transportSeptal penetrationDetector responseMC simulationsIterative reconstructionAttenuation distributionStandard OSEMPhotonsProjection dataPatient-specific activityDetectorReconstructed imagesScatteringEstimation of scattering
2006
Fast Monte Carlo Simulation Based Joint Iterative Reconstruction for Simultaneous 99mTc/123I Brain SPECT Imaging
Ouyang J, Fakhri G, Moore S, Kijewski M. Fast Monte Carlo Simulation Based Joint Iterative Reconstruction for Simultaneous 99mTc/123I Brain SPECT Imaging. 2006, 4: 2251-2256. DOI: 10.1109/nssmic.2006.354362.Peer-Reviewed Original ResearchMC-JOSEMAW-OSEMMonte CarloFast Monte CarloIterative reconstructionOrdered-subset expectation maximizationStandard ordered subsetsIterative reconstruction algorithmScattered photonsPhoton transportSeptal penetrationAttenuation distributionPhysical effectsIdentical physiological conditionsPatient-specific activityReconstructed imagesReconstruction algorithmActivity estimationComptonRoot mean square errorPhotonsCorrection methodCollimatorBrain perfusionDetector
2005
Collimator Optimization for Detection and Quantitation Tasks: Application to Gallium-67 Imaging
Moore S, Kijewski M, Fakhri G. Collimator Optimization for Detection and Quantitation Tasks: Application to Gallium-67 Imaging. IEEE Transactions On Medical Imaging 2005, 24: 1347-1356. PMID: 16229420, DOI: 10.1109/tmi.2005.857211.Peer-Reviewed Original ResearchMeSH KeywordsCitratesComputer SimulationComputer-Aided DesignEquipment DesignEquipment Failure AnalysisGalliumHumansImage EnhancementImage Interpretation, Computer-AssistedModels, BiologicalNeoplasmsPhantoms, ImagingPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificityConceptsMedium-energy low-penetration collimatorCollimator optimizationGeometric spatial resolutionPhotopeak energy windowSimulation of photon transportLead X-raysClinical imaging tasksActivity estimation taskSignal-to-noise ratioGallium-67 imagingContaminating photonsEnergy windowGeometric efficiencyCollimator designFixed energyPhoton transportOptimal collimatorCollimatorHotelling observerFWHMSpatial resolutionNuclear medicineDetectorResolution valuesImaging tasksRealistic Monte Carlo PET Simulation with Pixellated Block Detectors, Light Sharing and Randoms Modeling
Guérin B, Fakhri G. Realistic Monte Carlo PET Simulation with Pixellated Block Detectors, Light Sharing and Randoms Modeling. 2005, 3: 1563-1567. DOI: 10.1109/nssmic.2005.1596617.Peer-Reviewed Original ResearchPET scannerBlock detectorsPhoton transportRandom coincidencesSimSET softwareMonte Carlo transport codeNEMA NU 2Model of photon transportEnergy weighted averageModel photon transportLight-sharingEnergy spectrumNU 2Light sharingTransport codeCrystal elementsMonte Carlo simulationsPET simulationsVery good agreementInteraction pointPET acquisitionDetection crystalAttenuation distributionDetectorCarlo simulations
2002
Optimal Parallel-Hole Collimation for Lesion Detection and Activity Estimation in Ga-67 Imaging
Moore S, Kijewski M, Fakhri G. Optimal Parallel-Hole Collimation for Lesion Detection and Activity Estimation in Ga-67 Imaging. 2002, 3: 1390-1392. DOI: 10.1109/nssmic.2002.1239580.Peer-Reviewed Original ResearchCollimator designMedium-energy (MESimulation of photon transportSignal-to-noise ratioParallel-hole collimatorDesign of collimatorsClinical imaging tasksGa-67Contaminating photonsField of nuclear medicineEnergy windowFixed energyPhoton transportOptimal collimatorCollimatorCommercial collimatorsStaging of lymphoma patientsHotelling observerGa-67 imagingNuclear medicine clinicsLesion detectionNuclear medicineDetectorActivity concentrationsResolution values