2007
Validation of a Standardized Normalization Template for Statistical Parametric Mapping Analysis of 123I-FP-CIT Images
Kas A, Payoux P, Habert M, Malek Z, Cointepas Y, El Fakhri G, Chaumet-Riffaud P, Itti E, Remy P. Validation of a Standardized Normalization Template for Statistical Parametric Mapping Analysis of 123I-FP-CIT Images. Journal Of Nuclear Medicine 2007, 48: 1459-1467. PMID: 17704252, DOI: 10.2967/jnumed.106.038646.Peer-Reviewed Original ResearchConceptsStatistical parametric mappingDopamine transporterStatistical parametric mapping analysisIntraclass correlation coefficientStriatal (123)I-FP-CIT uptakeParkinson's diseaseStatistical parametric mapping approachEssential tremorBland-Altman graphical analysisStriatal volumeDopaminergic cell lossDAT imagingLow intraclass correlation coefficientsParametric mappingSpatial normalizationNo significant differencePD patientsCustomized templateIntergroup analysisCell lossSpatial normalization procedureResults of groupSPM normalizationSignificant differenceSPECTComparison of Brain PET and Sequential and Simultaneous Dual-isotope SPECT for Estimation Tasks in Normal and Parkinson Subjects
Trott C, Fakhri G. Comparison of Brain PET and Sequential and Simultaneous Dual-isotope SPECT for Estimation Tasks in Normal and Parkinson Subjects. 2007, 5: 3616-3620. DOI: 10.1109/nssmic.2007.4436906.Peer-Reviewed Original ResearchDopamine transporterEarly stages of PDDual-isotope SPECTStages of PDSequential SPECTDisease stageSimultaneous dual-isotope studyStriatal sizeBrain functionImprove patient managementEstimation taskDual-isotope studiesBrain PETDopamineClinical symptomsParkinson's diseasePatient managementSPECT imagesSpecific bindingMotor functionSPECTBrainEarly detectionActivity concentrationsIdentical physiological conditions
2005
Quantitative simultaneous 99mTc-ECD/123I-FP-CIT SPECT in Parkinson’s disease and multiple system atrophy
El Fakhri G, Habert M, Maksud P, Kas A, Malek Z, Kijewski M, Lacomblez L. Quantitative simultaneous 99mTc-ECD/123I-FP-CIT SPECT in Parkinson’s disease and multiple system atrophy. European Journal Of Nuclear Medicine And Molecular Imaging 2005, 33: 87-92. PMID: 16180033, DOI: 10.1007/s00259-005-1920-y.Peer-Reviewed Original ResearchConceptsMultiple system atrophyIdiopathic Parkinson's diseaseDopamine transporterDopamine transporter binding potentialNormal controlsVoxel-based statistical parametric mappingAsymmetry indexMultiple system atrophy patientsCompared to normal controlsCaudate nucleusDifferential diagnosis of idiopathic Parkinson’s diseaseDiagnosis of parkinsonian syndromesPatient-specific attenuationDiagnosis of idiopathic Parkinson's diseaseBinding potentialIdiopathic Parkinson's disease patientsDual-isotope SPECTVariable collimator responseParkinson's diseaseDifferential diagnosisDecreased perfusionStatistical parametric mappingPurposeThe purposeSystem atrophyParkinsonian syndromes
2003
Performance of Simultaneous and Sequential Tc-99m/I-123 SPECT Imaging in Estimation of Striatal Activity
Kijewski M, Fakhri G, Moore S. Performance of Simultaneous and Sequential Tc-99m/I-123 SPECT Imaging in Estimation of Striatal Activity. 2003, 5: 3134-3136. DOI: 10.1109/nssmic.2003.1352561.Peer-Reviewed Original Research