2024
User preferences for an mHealth app to support HIV testing and pre-exposure prophylaxis uptake among men who have sex with men in Malaysia
Palmer L, Wickersham J, Gautam K, Maviglia F, Bruno B, Azwa I, Khati A, Altice F, Paudel K, Pagoto S, Shrestha R. User preferences for an mHealth app to support HIV testing and pre-exposure prophylaxis uptake among men who have sex with men in Malaysia. PLOS Digital Health 2024, 3: e0000643. PMID: 39475851, PMCID: PMC11524455, DOI: 10.1371/journal.pdig.0000643.Peer-Reviewed Original ResearchHIV prevention servicesHIV testingPreventive servicesPre-exposure prophylaxis uptakeHIV prevention appIncrease HIV testingMobile appsPrevalence of HIVHard-to-reach populationsStudy assessed attitudesOnline focus groupsMalaysian MSMCost of servicesPrEP uptakeDedoose softwareMHealth appsPrevention appsFocus groupsIntervention modalitiesMSMEngagement strategiesHIVConfidentiality risksThematic contentMenCharacterizing a syndemic: STI symptoms, substance use & violence among incarcerated Peruvian women
Hashemi E, Cyrus E, Turpin R, Bazo A, Morgan-Lopez A, Scheidell J, Leon S, Altice F, Sciaudone M, Dyer T. Characterizing a syndemic: STI symptoms, substance use & violence among incarcerated Peruvian women. European Journal Of Public Health 2024, 34: ckae144.1502. PMCID: PMC11517018, DOI: 10.1093/eurpub/ckae144.1502.Peer-Reviewed Original ResearchIncarcerated womenSubstance useInterpersonal violenceSexually transmitted infection symptomsIncreased rates of incarcerationSexually transmitted infectionsExperiences of interpersonal violenceRates of incarcerationSTI symptomsLatent profile analysisViolenceLatent classesAt-risk populationsIncarcerationPrisonPeruvian womenEpidemiological dataSexual behaviorSymptomsLogistic regressionWomenBivariate analysisLatent profile analysis modelSubstancesIncreased rateIntegrated Online-to-Offline Model of Care for HIV Prevention and Treatment Among Men Who Have Sex With Men in Malaysia: Protocol for an Intervention Development and a Multiphase Trial
Khati A, Wickersham J, Gautam K, Paudel K, Phiphatkhunarnon P, Lim S, Puniamurthy K, Altice F, Phanuphak N, Azwa I, Shrestha R. Integrated Online-to-Offline Model of Care for HIV Prevention and Treatment Among Men Who Have Sex With Men in Malaysia: Protocol for an Intervention Development and a Multiphase Trial. JMIR Research Protocols 2024, 13: e60962. PMID: 39441624, PMCID: PMC11541154, DOI: 10.2196/60962.Peer-Reviewed Original ResearchA qualitative dyad analysis of barriers and facilitators of antiretroviral therapy (ART) adherence among people who inject drugs (PWID) with HIV in Kazakhstan
Neuenschwander P, Altice F, Remien R, Mergenova G, Sarsembayeva L, Rozental E, Gulyayev V, Davis A. A qualitative dyad analysis of barriers and facilitators of antiretroviral therapy (ART) adherence among people who inject drugs (PWID) with HIV in Kazakhstan. AIDS Care 2024, ahead-of-print: 1-10. PMID: 39404196, DOI: 10.1080/09540121.2024.2414078.Peer-Reviewed Original ResearchAntiretroviral therapy adherenceSocial supportART adherenceFacilitators of ART adherenceBarriers to ART adherenceAntiretroviral therapyART adherence interventionsInjection drug useDyad analysisAdherence interventionsAdherence barriersLack of awarenessHIV epidemicAdherencePWIDDrug useHIVInterpersonal levelRelationship contextDyad membersFacilitationIndividual levelPWHDyadsIntimate partnersDesign and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine
Machavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden L, Bromberg D, Haddad M, Morozova O, Ahmad B, Gómez D, Farnum S, Dvoriak S, Altice F. Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine. Contemporary Clinical Trials 2024, 146: 107690. PMID: 39265780, PMCID: PMC11531372, DOI: 10.1016/j.cct.2024.107690.Peer-Reviewed Original ResearchPrimary care centersQuality health indicatorsNon-communicable diseasesSpecialty treatment centersOpioid agonist therapyImplementation of integrated carePay-for-performance incentivesPrimary care clinicsPrimary care settingSelf-reported prevalencePay-for-performancePrevalence of medical comorbiditiesParticipants self-reportedEffective evidence-based treatmentsHealth of PWIDEvidence-based treatmentsIntegrated careCare clinicsImplementation outcomesImplementation trialCare settingsElectronic chart reviewHigh-burden countriesSpecialty servicesHIV prevalenceInterventions to reduce harms related to drug use among people who experience incarceration: systematic review and meta-analysis
Macdonald C, Macpherson G, Leppan O, Tran L, Cunningham E, Hajarizadeh B, Grebely J, Farrell M, Altice F, Degenhardt L. Interventions to reduce harms related to drug use among people who experience incarceration: systematic review and meta-analysis. The Lancet Public Health 2024, 9: e684-e699. PMID: 39214637, DOI: 10.1016/s2468-2667(24)00160-9.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentDrug useRisk behaviorsReducing re-arrestsTherapeutic community interventionsEffectiveness of interventionsRecidivism outcomesReduce injection risk behaviorExperience incarcerationRe-arrestIncarcerationService provisionRecidivismPrisonSystematic reviewCommunity interventionsSubstance useSelf-harmInjection risk behaviorsRandom-effects meta-analysesMeta-analysisAlcohol useSyringe sharingPooled odds ratioRisk of deathThe cascade of care for commercially-insured persons with opioid use disorder and comorbid HIV and HCV infections
Ivasiy R, Madden L, DiDomizio E, Johnson K, Machavariani E, Ahmad B, Oliveros D, Ram A, Kil N, Altice F. The cascade of care for commercially-insured persons with opioid use disorder and comorbid HIV and HCV infections. Drug And Alcohol Dependence 2024, 263: 112410. PMID: 39159600, DOI: 10.1016/j.drugalcdep.2024.112410.Peer-Reviewed Original ResearchOpioid use disorderXR-NTXUse disorderHCV infectionPrescribed MOUDOpioid use disorder cascadePrevalence of opioid use disorderRetrospective cohort studyHigher treatment retentionCascade of careConcurrent infectious diseasesSix-month retentionHCV/HIV coinfectionComorbid HIVCohort studyHospital-based settingPrescribed methadoneHCVMOUD initiationHIVHCV epidemicOpioidMethadoneMOUD prescriptionsTreatment retentionUsing nominal group technique to identify perceived barriers and facilitators to improving uptake of the Prison Needle Exchange Program in Canadian federal prisons by correctional officers and healthcare workers
Kronfli N, Lafferty L, Leone F, Stoové M, Hajarizadeh B, Lloyd A, Altice F. Using nominal group technique to identify perceived barriers and facilitators to improving uptake of the Prison Needle Exchange Program in Canadian federal prisons by correctional officers and healthcare workers. International Journal Of Drug Policy 2024, 130: 104540. PMID: 39079352, DOI: 10.1016/j.drugpo.2024.104540.Peer-Reviewed Original ResearchCorrectional officersCanadian federal prisonsFederal prisonsFear of beingNeedle exchange programsWrap-around servicesComplex application processCorrectional employeesFocus groupsPrisonNominal group techniquePerceived barriersAutomatic approvalFear of repercussionsHealthcare workersLack of confidentialityExchange programsSyringe programsOfficeDrug useCoverage of evidence-based interventionsCanadian effortsBloodborne virusesEvidence-based interventionsGroup techniqueHigh rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine
Ottesen T, Wickersham J, Lawrence J, Antoniak S, Zezuilin O, Polonsky M, Antonyak S, Rozanova J, Dvoriak S, Pykalo I, Filippovych M, Altice F. High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine. PLOS ONE 2024, 19: e0305086. PMID: 39028735, PMCID: PMC11259278, DOI: 10.1371/journal.pone.0305086.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy prescriptionAntiretroviral therapyCD4 countSubstance use disordersIncreased levels of stigmaNational sampleLevel of stigmaIndependent of risk groupSuboptimal antiretroviral therapyInitiate antiretroviral therapyPopulation of peopleHIV expertsHIV incidenceHIV physiciansHIV treatmentKey populationsTransgender womenAntiretroviral treatmentFeeling thermometerDrinking alcoholSex workersPhysiciansSex partnersPWHRisk groupsW96 Scaling up Opioid Agonist Therapies in Ukraine Before the War: Implementation Factors Related to Disruptions From Legislative Reform and COVID-19
Madden L, Ivasiy R, Polonsky M, Farnum S, Galvez S, Meteliuk A, Bromberg D, Altice F. W96 Scaling up Opioid Agonist Therapies in Ukraine Before the War: Implementation Factors Related to Disruptions From Legislative Reform and COVID-19. Drug And Alcohol Dependence 2024, 260: 110714. DOI: 10.1016/j.drugalcdep.2023.110714.Peer-Reviewed Original ResearchPrevalence and Correlates of Depression and Bipolar Disorder Among Patients Maintained on Methadone and Buprenorphine in Ukraine
Morozova O, Dvoriak V, Dumchev K, Machavariani E, Bromberg D, Dvoriak S, Altice F. Prevalence and Correlates of Depression and Bipolar Disorder Among Patients Maintained on Methadone and Buprenorphine in Ukraine. International Journal Of Mental Health And Addiction 2024, 1-18. DOI: 10.1007/s11469-024-01353-6.Peer-Reviewed Original ResearchCorrelates of depressionBipolar disorderUse disorderPrevalence of psychiatric disordersBurden of mental health disordersCo-occurring disordersAlcohol use disorderSubstance use disordersMental health disordersIntegrated care strategiesCluster randomized trialAnalyzed baseline dataOpioid use disorderPsychiatric disordersMethadone dosageDepression diagnosisStigma levelsPHQ-9Moderate/severe depressionHealth disordersDepressionCare strategiesPhysical healthDrug injectionDisordersAlcohol Use Disorder and HIV Risk in a National Survey of Men Who Have Sex with Men in Ukraine
Gabriel W, Sazonova Y, Kulchynska R, LaMonaca K, Salyuk T, Smyrnov P, Altice F. Alcohol Use Disorder and HIV Risk in a National Survey of Men Who Have Sex with Men in Ukraine. International Journal Of Behavioral Medicine 2024, 1-17. PMID: 38914921, DOI: 10.1007/s12529-024-10272-8.Peer-Reviewed Original ResearchHIV transmission riskAssociated with HIV transmissionAlcohol use disorderHIV transmissionAlcohol consumptionTargeted HIV prevention strategiesPotential alcohol use disordersBehaviors associated with HIV transmissionRisk behaviors associated with HIV transmissionUnknown HIV statusHIV prevention strategiesPrevalent HIV infectionAssociated with increased likelihoodLikelihood of HIV acquisitionPre-exposure prophylaxisMultivariate regressionProblematic alcohol consumptionUse disorderConclusionThe high prevalenceMSM participantsHIV testingProblematic alcohol useHIV incidenceHIV statusHIV riskHIV Activist Identity, Commitment, and Orientation Scale (HAICOS): Psychometric Evaluation to Assess Clinician’s Propensity Towards HIV Activism in Malaysia
Chong N, Azwa I, Hassan A, Mousavi M, Wong P, Ng R, Saifi R, Basri S, Omar S, Walters S, Collier Z, Haddad M, Altice F, Kamarulzaman A, Earnshaw V. HIV Activist Identity, Commitment, and Orientation Scale (HAICOS): Psychometric Evaluation to Assess Clinician’s Propensity Towards HIV Activism in Malaysia. AIDS And Behavior 2024, 28: 2780-2792. PMID: 38806844, DOI: 10.1007/s10461-024-04381-4.Peer-Reviewed Original ResearchConceptsExploratory factor analysisHIV-related stigmaIntra-class correlation coefficientPrimary care physiciansTest-retest reliabilityCronbach's alpha valuesOrientation ScaleCare physiciansStigma-relatedPsychometric evaluationHIV treatmentHIV activityAlpha valuesPsychometric qualitiesActivist identitiesHIVClinical practiceFactor analysisCliniciansCorrelation coefficientDay-to-dayStructured activitiesCronbachStigmaPhysiciansThe impact of emergency guidance to the COVID‐19 pandemic on treatment entry, retention and mortality among patients on methadone in Ukraine
Ivasiy R, Madden L, Meteliuk A, Machavariani E, Ahmad B, Zelenev A, Desai M, Bromberg D, Polonsky M, de Leon S, Farnum S, Islam Z, Altice F. The impact of emergency guidance to the COVID‐19 pandemic on treatment entry, retention and mortality among patients on methadone in Ukraine. Addiction 2024, 119: 1585-1596. PMID: 38807448, DOI: 10.1111/add.16565.Peer-Reviewed Original ResearchOpioid agonist therapyTake-home dosesCOVID-19 guidancePre-COVID cohortAgonist therapyOptimal doseTreatment retentionEmergency guidanceEffective HIV prevention strategiesAdult HIV prevalenceHIV prevention strategiesMinistry of HealthImprove treatment retentionMethadone dosePatient survivalTime-dependent predictorsProspective cohortHIV prevalencePredictors of treatment retentionGovernmental clinicsPrimary outcomeHazard ratioPatient enrollmentPatientsMethadone patientsUsing Voice Data to Facilitate Depression Risk Assessment in Primary Health Care
Goyal A, Man R, Lee R, Saha K, Altice F, Poellabauer C, Papakyriakopoulos O, Cheung L, De Choudhury M, Allagh K, Kumar N. Using Voice Data to Facilitate Depression Risk Assessment in Primary Health Care. 2024, 17-18. DOI: 10.1145/3630744.3658408.Peer-Reviewed Original ResearchDepression riskPrimary health careDepression risk assessmentLower-income patientsHealth careTreating depressionVoice dataDepressionK-nearest neighbor classifierMachine learning algorithmsCollected voice dataRiskNeighbor classifierLearning algorithmsStable internet connectionK-nearestInternet connectionTelehealthCareUsing Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial
Machavariani E, Miceli J, Altice F, Fanfair R, Speers S, Nichols L, Jenkins H, Villanueva M. Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024, 96: 40-50. PMID: 38324241, PMCID: PMC11009056, DOI: 10.1097/qai.0000000000003391.Peer-Reviewed Original ResearchDisease intervention specialistsCare continuum outcomesHIV care continuum outcomesHIV care continuumRandomized controlled trialsHIV risk categoryCare continuumStandard-of-careData-to-CareViral suppressionRe-engagementPredictor of re-engagementRisk categoriesHIV careRe-engage peopleMultivariate regression modelHIV clinicPredictors of retentionDetectable HIV-1 RNAIntervention specialistsControlled trialsPredictors of VSPre-randomizationCareHIV-1 RNAHigher methadone dose at time of release from prison predicts linkage to maintenance treatment for people with HIV and opioid use disorder transitioning to the community in Malaysia
Ahmad A, Bromberg D, Shrestha R, Salleh N, Bazazi A, Kamarulzaman A, Shenoi S, Altice F. Higher methadone dose at time of release from prison predicts linkage to maintenance treatment for people with HIV and opioid use disorder transitioning to the community in Malaysia. International Journal Of Drug Policy 2024, 126: 104369. PMID: 38484531, PMCID: PMC11056294, DOI: 10.1016/j.drugpo.2024.104369.Peer-Reviewed Original ResearchMethadone maintenance treatmentNational Institute of Drug AbuseMethadone dosePost-releaseOpioid dependenceMaintenance treatmentMethadone maintenance treatment doseHigher doses of methadoneProspective trialsHighest methadone dosagePost-release outcomesHigher methadone dosesMalaysia’s largest prison.Levels of depressionTreatment of opioid use disorderMonths of releaseDose of methadoneOpioid use disorderLargest prisonHigher dosageIncarcerated peopleIncarceration periodUse disorderMethadone dosageTime-to-event analysisIntegrating methadone into primary care settings in Ukraine: effects on provider stigma and knowledge
Bromberg D, Machavariani E, Madden L, Dumchev K, LaMonaca K, Earnshaw V, Pykalo I, Filippovych M, Haddad M, Dvoriak S, Altice F. Integrating methadone into primary care settings in Ukraine: effects on provider stigma and knowledge. Journal Of The International AIDS Society 2024, 27: e26202. PMID: 38379179, PMCID: PMC10879646, DOI: 10.1002/jia2.26202.Peer-Reviewed Original ResearchConceptsPrimary care clinicsStigma reduction interventionsOpioid agonist therapyClinicians' attitudesStigma constructsHIV preventionReduction interventionsEvidence-based HIV preventionCluster randomized controlled trialEvidence-based carePrimary care settingIntegrated care sitesDirect providersRandomized controlled trialsProvider stigmaCare clinicsCare sitesHIV careCare settingsHealth outcomesClinical staffSubstance use disordersLinear mixed-effects modelsTreatment continuumImprove attitudesImplementation of Chatbot Technology in Health Care: Protocol for a Bibliometric Analysis
Ni Z, Peng M, Balakrishnan V, Tee V, Azwa I, Saifi R, Nelson L, Vlahov D, Altice F. Implementation of Chatbot Technology in Health Care: Protocol for a Bibliometric Analysis. JMIR Research Protocols 2024, 13: e54349. PMID: 38228575, PMCID: PMC10905346, DOI: 10.2196/54349.Peer-Reviewed Original ResearchChatbot technologyBibliometric analysisChatbot researchSoftware tool VOSviewerINTERNATIONAL REGISTERED REPORT IDENTIFIERVisualize bibliometric networksHealth care systemArtificial intelligence chatbotsHealth careIntelligent chatbotAI engineAdoption of chatbotsConversational agentsScreening of papersBibliometric networksIEEE XploreCare systemChatbotPublication patternsSearch phaseAnalysis of publicationsHealth-related informationSoftware toolsAnnual publicationsInstitutional distributionTesting the Feasibility and Acceptability of Using an Artificial Intelligence Chatbot to Promote HIV Testing and Pre-Exposure Prophylaxis in Malaysia: Mixed Methods Study.
Cheah M, Gan Y, Altice F, Wickersham J, Shrestha R, Salleh N, Ng K, Azwa I, Balakrishnan V, Kamarulzaman A, Ni Z. Testing the Feasibility and Acceptability of Using an Artificial Intelligence Chatbot to Promote HIV Testing and Pre-Exposure Prophylaxis in Malaysia: Mixed Methods Study. JMIR Human Factors 2024, 11: e52055. PMID: 38277206, PMCID: PMC10858413, DOI: 10.2196/52055.Peer-Reviewed Original ResearchConceptsUptake of HIV testingHIV testingPre-exposure prophylaxisUnified Theory of AcceptanceFrequency of HIV testingTheory of AcceptanceAI chatbotsPromote HIV testingMental health supportHIV risk assessmentHIV prevention effortsHIV-related informationMixed methods studyPresence of stigmaUse of TechnologyConsequences of HIVEffort expectancySexually transmitted infectionsWeb-based surveyEngaging MSMArtificial intelligenceTranscribed verbatimPrEP uptakeHealth supportMental health