2024
Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine
Machavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden L, Bromberg D, Haddad M, Morozova O, Ahmad B, Gómez D, Farnum S, Dvoriak S, Altice F. Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine. Contemporary Clinical Trials 2024, 146: 107690. PMID: 39265780, PMCID: PMC11531372, DOI: 10.1016/j.cct.2024.107690.Peer-Reviewed Original ResearchPrimary care centersQuality health indicatorsNon-communicable diseasesSpecialty treatment centersOpioid agonist therapyImplementation of integrated carePay-for-performance incentivesPrimary care clinicsPrimary care settingSelf-reported prevalencePay-for-performancePrevalence of medical comorbiditiesParticipants self-reportedEffective evidence-based treatmentsHealth of PWIDEvidence-based treatmentsIntegrated careCare clinicsImplementation outcomesImplementation trialCare settingsElectronic chart reviewHigh-burden countriesSpecialty servicesHIV prevalenceIntegrating methadone into primary care settings in Ukraine: effects on provider stigma and knowledge
Bromberg D, Machavariani E, Madden L, Dumchev K, LaMonaca K, Earnshaw V, Pykalo I, Filippovych M, Haddad M, Dvoriak S, Altice F. Integrating methadone into primary care settings in Ukraine: effects on provider stigma and knowledge. Journal Of The International AIDS Society 2024, 27: e26202. PMID: 38379179, PMCID: PMC10879646, DOI: 10.1002/jia2.26202.Peer-Reviewed Original ResearchConceptsPrimary care clinicsStigma reduction interventionsOpioid agonist therapyClinicians' attitudesStigma constructsHIV preventionReduction interventionsEvidence-based HIV preventionCluster randomized controlled trialEvidence-based carePrimary care settingIntegrated care sitesDirect providersRandomized controlled trialsProvider stigmaCare clinicsCare sitesHIV careCare settingsHealth outcomesClinical staffSubstance use disordersLinear mixed-effects modelsTreatment continuumImprove attitudes
2022
Preliminary analysis of self-reported quality health indicators of patients on opioid agonist therapy at specialty and primary care clinics in Ukraine: A randomized control trial
Pashchenko O, Bromberg D, Dumchev K, LaMonaca K, Pykalo I, Filippovych M, Esserman D, Polonsky M, de Leon S, Morozova O, Dvoriak S, Altice F. Preliminary analysis of self-reported quality health indicators of patients on opioid agonist therapy at specialty and primary care clinics in Ukraine: A randomized control trial. PLOS Global Public Health 2022, 2: e0000344. PMID: 36962514, PMCID: PMC10021202, DOI: 10.1371/journal.pgph.0000344.Peer-Reviewed Original ResearchPrimary care clinicsOpioid use disorderOpioid agonist therapyPrimary careComplete self-reported dataPatient medical record dataMedical record dataComprehensive health outcomesAddiction treatment clinicsAdult PWIDAgonist therapySecondary outcomesParent trialPrimary outcomeRandomized participantsCare clinicsTreatment clinicsIntervention sitesUse disordersHealth outcomesAddiction treatmentRecord dataSelf-reported dataHealth indicatorsClinic
2021
Successful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study
Meteliuk A, Galvez S, Fomenko T, Kalandiia H, Iaryi V, Farnum SO, Islam Z, Altice FL, Madden LM. Successful transfer of stable patients on opioid agonist therapies from specialty addiction treatment to primary care settings in Ukraine: A pilot study. Journal Of Substance Use And Addiction Treatment 2021, 134: 108619. PMID: 34579978, DOI: 10.1016/j.jsat.2021.108619.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyPrimary care clinicsPrimary care settingOAT coverageAgonist therapyStable patientsCare clinicsSubstance useCare settingsNegative urine drug testsSpecialty addictions treatmentUrine drug testsSymptom Identification ScaleMental health symptomsAddiction treatment clinicsHIV transmissionPrimary careTreatment clinicsOAT patientsBASIS-24PatientsHealth symptomsEmotional labilityAddiction treatmentPilot studyStructural barriers to implementing recommended tuberculosis preventive treatment in primary care clinics in rural South Africa
Chandra DK, Moll AP, Altice FL, Didomizio E, Andrews L, Shenoi SV. Structural barriers to implementing recommended tuberculosis preventive treatment in primary care clinics in rural South Africa. Global Public Health 2021, 17: 555-568. PMID: 33650939, PMCID: PMC8410883, DOI: 10.1080/17441692.2021.1892793.Peer-Reviewed Original ResearchConceptsTuberculosis preventive treatmentPrimary healthcare clinicsTPT initiationWorld Health OrganizationAntiretroviral therapyPreventive treatmentRural South AfricaHIV/TB servicesBurden of HIVOnly independent correlatePrimary care clinicsClinic-level factorsPatient-level characteristicsPrimary care providersHealth Services frameworkEvidence-based strategiesQuality improvement strategiesTB servicesClinical factorsCare clinicsIndependent correlatesMedical recordsPromoting ActionCare providersHealthcare clinics
2016
Acceptability and feasibility of mHealth and community-based directly observed antiretroviral therapy to prevent mother-to-child HIV transmission in South African pregnant women under Option B+: an exploratory study
Nachega JB, Skinner D, Jennings L, Magidson JF, Altice FL, Burke JG, Lester RT, Uthman OA, Knowlton AR, Cotton MF, Anderson JR, Theron GB. Acceptability and feasibility of mHealth and community-based directly observed antiretroviral therapy to prevent mother-to-child HIV transmission in South African pregnant women under Option B+: an exploratory study. Patient Preference And Adherence 2016, Volume 10: 683-690. PMID: 27175068, PMCID: PMC4854240, DOI: 10.2147/ppa.s100002.Peer-Reviewed Original ResearchFeasibility of mHealthHIV status disclosurePregnant womenAntiretroviral therapyTreatment supportersStatus disclosureChild human immunodeficiency virus (HIV) transmissionCommunity primary care clinicsHuman immunodeficiency virus (HIV) transmissionPregnant South African womenART adherence interventionsAntiretroviral therapy regimenChild HIV transmissionAntiretroviral therapy adherencePrimary care clinicsSouth African pregnant womenMobile phone accessAfrican pregnant womenFocus group discussionsSMS text messagingPMTCT servicesSouth African womenART adherencePhone accessTherapy regimen
2015
Advancing Behavioral HIV Prevention: Adapting an Evidence‐Based Intervention for People Living with HIV and Alcohol Use Disorders
Armstrong ML, LaPlante AM, Altice FL, Copenhaver M, Molina PE. Advancing Behavioral HIV Prevention: Adapting an Evidence‐Based Intervention for People Living with HIV and Alcohol Use Disorders. AIDS Research And Treatment 2015, 2015: 879052. PMID: 26697216, PMCID: PMC4678056, DOI: 10.1155/2015/879052.Peer-Reviewed Original ResearchEvidence-based interventionsAlcohol use disorderDisease progressionHIV preventionUse disordersAlcohol consumptionHIV primary care clinicHolistic Health Recovery ProgramAdapted evidence-based interventionSecondary HIV preventionHIV disease progressionAntiretroviral therapy adherencePrimary care clinicsSuboptimal treatment adherenceHIV risk behaviorsHeavy alcohol consumptionBehavioral HIV preventionHarmful alcohol consumptionHeavy alcohol useHIV/AIDSFocus groupsCare clinicsTherapy adherenceTreatment adherenceOutpatient options